50 Results for "

MTC

" in MedChemExpress (MCE) Product Catalog:
Products (50)

50 Results for "MTC" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-47979
CAS No.: 2471983-20-5
Target:  

FAP

Research Areas:  

Cancer

FAP-IN-2 is an isonitrile-containing fibroblast activation protein (FAP) inhibitor. FAP-IN-2 can be labeled with technetium-99m ( 99mTc) for targeted tumor SPECT imaging .
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1
1 Cited Publications
Cat. No.: HY-148152
CAS No.: 2639475-07-1
Target:  

PSMA

Research Areas:  

Others

PSMA I&S is a precursor of the 99mTc-labeled PSMA-targeting ligand .
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1
1 Cited Publications
Cat. No.: HY-47979A
Target:  

FAP

Research Areas:  

Cancer

FAP-IN-2 TFA is an isonitrile-containing fibroblast activation protein (FAP) inhibitor. FAP-IN-2 TFA can be labeled with technetium-99m ( 99mTc) for targeted tumor SPECT imaging .
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1
1 Cited Publications
Cat. No.: HY-P7308
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuTrkA; NTRK1; MTC; TRK
Species:  
Source:  
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Cat. No.: HY-P99160
CAS No.: 219649-07-7
Synonyms: hMN14

Research Areas:  

Cancer

Labetuzumab is a humanised anti-carcinoembryonic antigen (CEA) monoclonal antibody that inhibits tumour growth and sensitises human medullary thyroid cancer xenografts to Dacarbazine chemotherapy .
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Cat. No.: HY-W094510
CAS No.: 13472-36-1
Sodium pyrophosphate decahydrate is a phosphate donor and mild chelating agent. Sodium pyrophosphate decahydrate serves as a phosphate source for Pseudomonas aeruginosa acid phosphatase and its Q6 variant, enabling phosphorylation of L‑ascorbic acid to L‑ascorbate‑2‑phosphate. Sodium pyrophosphate decahydrate facilitates 99mTc labeling of human polyclonal IgG. Sodium pyrophosphate decahydrate can be used in research on musculoskeletal infections .
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Cat. No.: HY-W009776
CAS No.: 38937-66-5
Synonyms: Suberohydroxamic acid; SBHA
Target:  

HDAC Apoptosis

Research Areas:  

Cancer

Suberoyl bis-hydroxamic acid (Suberohydroxamic acid; SBHA) is a competitive and cell-permeable HDAC1 and HDAC3 inhibitor with ID50 values of 0.25 μM and 0.30 μM, respectively .Suberoyl bis-hydroxamic acid renders MM cells susceptible to apoptosis and facilitates the mitochondrial apoptotic pathways .Suberoyl bis-hydroxamic acid can be used for the study of medullary thyroid carcinoma (MTC) .
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Cat. No.: HY-U00432A
CAS No.: 209589-59-3
Synonyms: S-Methyl-L-thiocitrulline dihydrochloride
Target:  

NO Synthase

Research Areas:  

Neurological Disease

S-MTC (S-Methyl-L-thiocitrulline) dihydrochloride is a selective type I nitric oxide synthase (NOS) inhibitor.
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Cat. No.: HY-P10369
CAS No.: 103725-47-9
Betiatide, as a chelating agent for Technetium-99m ( 99mTc), is used to prepare 99mTc-MAG3 (mercaptoacetyltriglycine), a radiopharmaceutical for renal function imaging. Betiatide is used for the diagnosis of congenital and acquired abnormalities, renal failure, urinary tract obstructions, and calculi . Betiatide can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).
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Cat. No.: HY-P10913
CAS No.: 1186217-15-1
Target:  

Bacterial

Research Areas:  

Infection

HYNIC-UBI29-41 is composed of a bifunctional chelator HYNIC and an antimicrobial peptide UBI 29-41 (HY-P10364) (HY-P10364). HYNIC-UBI29-41 retains the antibacterial properties of UBI 29-41, and exhibits good affinity to Gram-positive and Gram-negative bacteria. HYNIC-UBI29-41 can be used as an imaging agent for bacterial infection detection in mouse models, when labeled with the radioactive element technetium (99mTc) .
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Cat. No.: HY-P10792
CAS No.: 1644155-35-0
Target:  

EGFR

Research Areas:  

Cancer

HER2-targeted peptide H6F is a HER2 targeting peptide that binds to HER2 to target breast cancer cells, with the amino acid sequence YLFFVFER. The HER2-targeted peptide H6F can be conjugated with the bifunctional chelating agent hydrazinonicotinamide (HYNIC) for radiolabeling with 99mTc. Single-photon emission computed tomography (SPECT) imaging shows that the labeled HER2-targeted peptide H6F specifically accumulates in HER2-positive MDA-MBA-453 tumor-bearing mice models. The HER2-targeted peptide H6F can be used for tumor molecular imaging studies .
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Cat. No.: HY-P5292A
CAS No.: 2375849-11-7
Research Areas:  

Cancer

HYNIC-iPSMA TFA is a ligand for molecular imaging of tumors. Hynic-ipsma consists of two components: HYNIC (6-hydrazinonicotinamide) and iPSMA (Inhibitor of Prostate-Specific Membrane Antigen). HYNIC is a compound used to attach radioactive isotopes to targeted molecules. iPSMA is a specific inhibitor used to inhibit prostate-specific membrane antigen (PSMA). 68GA-labeled iPSMA has been used to detect prostate cancer by PET imaging. The further 99mTc-EDDA/HYNIC-iPSMA TFA has excellent specificity and sensitivity . HYNIC-iPSMA TFA can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).
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Cat. No.: HY-P99691
CAS No.: 250242-54-7
Synonyms: IMMU-MN3
Lemalesomab (IMMU-MN3) is a Fab' fragment of a murine anti-granulocyte monoclonal antibody targeting NCA-90 (CEACAM6). Lemalesomab binds strongly to NCA-90 on the surface of granulocytes, cross-reacts with epitopes of other CEA family members, and blocks the binding between human colon adenocarcinoma cells and CEA. When labeled with 99mTc, Lemalesomab can be used for radionuclide imaging of soft tissue infections and osteomyelitis .
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Cat. No.: HY-P5292
CAS No.: 2192215-74-8
Research Areas:  

Cancer

HYNIC-iPSMA is a ligand for molecular imaging of tumors. Hynic-ipsma consists of two components: HYNIC (6-hydrazinonicotinamide) and iPSMA (Inhibitor of Prostate-Specific Membrane Antigen). HYNIC is a compound used to attach radioactive isotopes to targeted molecules. iPSMA is a specific inhibitor used to inhibit prostate-specific membrane antigen (PSMA). 68GA-labeled iPSMA has been used to detect prostate cancer by PET imaging. The further 99mTc-EDDA/HYNIC-iPSMA has excellent specificity and sensitivity . HYNIC-iPSMA can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).
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Cat. No.: HY-U00432
CAS No.: 156719-41-4
Synonyms: S-Methyl-L-thiocitrulline
Target:  

NO Synthase

Research Areas:  

Neurological Disease

S-MTC is a selective type I nitric oxide synthase (NOS) inhibitor.
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Cat. No.: HY-114133
CAS No.: 161982-62-3
Depreotide is a nove tumor tarcer, can be complexed with technetium-99m ( 99mTc-depreotide) for optimal imaging properties. 99mTc-depreotide somatostain receptor imaging has been playing an important role in medical diagnosis research . Depreotide can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).
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Cat. No.: HY-145769
CAS No.: 2547100-02-5
Target:  

PD-1/PD-L1

Research Areas:  

Cancer

N2S2-CBMBC, an N2S2 bromo-benzyl ether derivative, acts as a ligand and use 99mTc-labelled complexes 99mTc-N2S2-CBMBC can be used as an imaging agent to be applied to the aspect of detecting PD-L1 expression, realize the real-time, comprehensive and convenient detection of the PD-L1 level of tumors, and overcome the defects of an immunohistochemical method .
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Cat. No.: HY-172366
CAS No.: 3055338-52-5
Target:  

PSMA

Research Areas:  

Cancer

BQ0413 exhibits good affinity to PSMA with a KD of 89 pM. BQ0413 exhibits good uptake and internalization property with an internalization rate of 44% in PC3-pip cell. BQ0413 can be used as tumor imaging agent when labeled with 99mTc .
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Cat. No.: HY-P10913A
Target:  

Bacterial

Research Areas:  

Infection

HYNIC-UBI29-41 TFA is composed of a bifunctional chelator HYNIC and an antimicrobial peptide UBI 29-41 (HY-P10364). HYNIC-UBI29-41 TFA retains the antibacterial properties of UBI 29-41, and exhibits good affinity to Gram-positive and Gram-negative bacteria. HYNIC-UBI29-41 TFA can be used as an imaging agent for bacterial infection detection in mouse models, when labeled with the radioactive element technetium (99mTc) .
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Cat. No.: HY-P5520
CAS No.: 2413262-74-3
GB-6 is a short linear peptide that targets the gastrin releasing peptide receptor (GRPR). GRPR is overexpressed in pancreatic cancer. Based on the tumor selectivity and tumor-specific accumulation properties of GB-6, GB-6 labeled with near infrared (NIR) fluorescent dyes or radionuclide netium-99m (99mTc) can be used as a high-contrast imaging probe. GB-6 has excellent in vivo stability, with tumor to pancreatic and intestinal fluorescence signal ratios of 5.2 and 6.3, respectively, in SW199 0 subcutaneous xenograft models. GB-6 can rapidly target tumors and accurately delineate tumor boundaries, which has broad application prospects .
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