55 Results for "

NKG2D

" in MedChemExpress (MCE) Product Catalog:
Products (55)

55 Results for "NKG2D" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-N0434
CAS No.: 84687-42-3
Astragaloside III is a triterpenoid saponin. Astragaloside III can be extracted from Astragalus root. Astragaloside III increases NKG2D and induces TACE phosphorylation. Astragaloside III induces Apoptosis. Astragaloside III has antiviral activity against dengue serotypes 1 and 3. Astragaloside III has anticancer activity against breast and colon cancer [2] .
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1 Cited Publications
Cat. No.: HY-125938
CAS No.: 21238-33-5
Purity:  98.98%
Synonyms: Cycloartenol ferulate; Cycloartenol ferulic acid ester
Cycloartenyl ferulate (Cycloartenol ferulate; Cycloartenol ferulic acid ester) is a derivative of γ-oryzanol (HY-B2194) with multiple biological activities including antioxidant, anti-inflammatory, and anti-tumor properties. Cycloartenyl ferulate selectively binds to IFNγR1 (binding affinity Kd = 0.5 μM) to activate the canonical JAK1/2-STAT1 signaling pathway. Cycloartenyl ferulate inhibits paraquat (PQ)-triggered apoptosis and ROS in HK2 cells. Cycloartenyl ferulate enhances the activation and cytolytic activity of natural killer (NK) cells by upregulating the expression of NK cell activation receptors (NKG2D, NKp30, NKp44) and the release of cytotoxic molecules and cytokine IFNγ. Cycloartenyl ferulate exerts anti-cancer effects in tumor mice models. Cycloartenyl ferulate can be used for the study of cancer and allergic inflammation intervention [2] .
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1 Cited Publications
Cat. No.: HY-P72503
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NKG2-D type II integral membrane protein; CD314; KLRK1; NKG2-D
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Cat. No.: HY-P99389
CAS No.: 2242758-08-1
Synonyms: JNJ-64304500; IPH-2301; NN-8555
Tesnatilimab (JNJ-64304500) is a human IgG4 monoclonal antibody targeting NKG2D, with a KD value of 9.2 pM [2]. Tesnatilimab blocks the binding of ligands to the NKG2D receptor, thereby inhibiting downstream proinflammatory cytokine, cytotoxic mediator signaling pathways and proinflammatory immune responses. Tesnatilimab is applicable to research related to Crohn's disease [2].
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Cat. No.: HY-155311
NKG2D-IN-1 (compound 21) is a natural killer group 2D receptor (NKG2D) inhibitor. NKG2D-IN-1 inhibits the protein-protein interaction between NKG2D and its ligands MICA and ULBP6, with IC50 values of 0.3 μM and 0.7 μM. NKG2D-IN-1 can be used in the research of autoimmune diseases .
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Cat. No.: HY-P990178
Anti-Mouse NKG2D/CD314 Antibody (CX5) is a rat-derived IgG1 κ type antibody inhibitor, targeting to mouse NKG2D/CD314. Anti-Mouse NKG2D/CD314 Antibody (CX5) reduces cytotoxicity of natural killer cells. Anti-Mouse NKG2D/CD314 Antibody (CX5) can be used for the researches of cancer, infection, inflammation, immunology and metabolic disease, such as colitis and diabetes [2] .
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Cat. No.: HY-155312
Research Areas:  

Cancer

NKG2D-IN-2 (compound 47) is a natural killer group 2D receptor (NKG2D) inhibitor with IC50s of 0.1 µM and 0.2 µM in NKG2D/MICA and ULBP6 TR-FRET assays, respectively .
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Cat. No.: HY-P992071
Anti-Mouse NKG2D Antibody (MI6) is an antibody targeting mouse NKG2D. Anti-Mouse NKG2D Antibody (MI6) can be used in arthritis-related research. For the isotype control of Anti-Mouse NKG2D Antibody (MI6), please refer to Rat IgG1 kappa, Isotype Control (HY-P99979) .
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Cat. No.: HY-P992068

Research Areas:  

Others

Anti-Human/Monkey NKG2D Antibody (ON72) is an antibody targeting human/monkey NKG2D. The isotype control for Anti-Human/Monkey NKG2D Antibody (ON72) can be referenced as Mouse IgG1 kappa, Isotype Control (HY-P99977).
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Cat. No.: HY-P992069

Research Areas:  

Others

Anti-Human/Mouse NKG2D Antibody (ADI-27724) is an antibody targeting human/mouse NKG2D. The isotype control for Anti-Human/Mouse NKG2D Antibody (ADI-27724) can be referenced as Mouse IgG1 kappa, Isotype Control (HY-P99977).
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Cat. No.: HY-P992067

Research Areas:  

Others

Anti-Human/Monkey NKG2D Antibody (16F16) is an antibody targeting human/monkey NKG2D. The isotype control for Anti-Human/Monkey NKG2D Antibody (16F16) can be referenced as Human IgG4 kappa, Isotype Control (HY-P99003).
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Cat. No.: HY-P992070

Research Areas:  

Others

Anti-Human/Mouse NKG2D Antibody (ADI-27740) is an antibody targeting human/mouse NKG2D. The recommended isotype control for this antibody is Mouse IgG1 kappa, Isotype Control (HY-P99977).
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Cat. No.: HY-P990829

Research Areas:  

Infection

Anti-NKG2D/CD314 Antibody (1D11) is a kind of mouse IgG1 κ chimeric antibody, targeting to human NKG2D/CD314. Anti-NKG2D/CD314 Antibody (1D11) can block the binding of NKG2D to its ligands. Anti-NKG2D/CD314 Antibody (1D11) can be used for the research of infection, such as HIV (human immunodeficiency virus) .
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Cat. No.: HY-P990804
Anti-Mouse NKG2D/CD314 Antibody (HMG2D) is an Armenian hamster-derived IgG antibody inhibitor, targeting to mouse NKG2D/CD314. Anti-Mouse NKG2D/CD314 Antibody (HMG2D) can block NKG2D. Anti-Mouse NKG2D/CD314 Antibody (HMG2D) can be used for the researches of cancer, infection, inflammation and immunology, such as B16F10 tumor, colitis and L. major parasites and lymphocytic choriomeningitis virus (LCMV) co-infection [2] .
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Cat. No.: HY-P991606
TRX585 is a humanised anti-immunoglobulin-like transcript 5 (ILT5) monoclonal antibody. TRX585 has a potent immunoregulatory activity. TRX585 significantly activates human T cells and upregulates NKG2D and Fas ligand, followed by enhancing antitumor activity with potent cytotoxicity. TRX585 can be used for viral infections and malignancies research .
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Cat. No.: HY-N0434R
CAS No.: 84687-42-3
Astragaloside III (Standard) is the analytical standard of Astragaloside III (HY-N0434). This product is intended for research and analytical applications. Astragaloside III is a triterpenoid saponin. Astragaloside III can be extracted from Astragalus root. Astragaloside III increases NKG2D and induces TACE phosphorylation. Astragaloside III induces Apoptosis. Astragaloside III has antiviral activity against dengue serotypes 1 and 3. Astragaloside III has anticancer activity against breast and colon cancer [2] .
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Cat. No.: HY-P78330
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CD314; D12S2489E; KLR; NKG2-D; NKG2D
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Cat. No.: HY-P78498
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CD314; D12S2489E; KLR; NKG2-D; NKG2D
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Cat. No.: HY-P78500
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CD314; D12S2489E; KLR; NKG2-D; NKG2D
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Cat. No.: HY-P705066
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD314; D12S2489E; KLR; NKG2-D; NKG2D
Species:  
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