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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
42 Results for "
PEX
" in MedChemExpress (MCE) Product Catalog:
Products (42)
42 Results for "PEX" in MCE Product Catalog:
8
8 Cited Publications
MMP-9-IN-1 is a specific matrix metalloproteinase-9 (MMP-9) inhibitor, which
selectively target the hemopexin (PEX) domain of MMP-9, but not other MMPs .
Cat. No.: HY-155531
CAS No.: 3052256-03-5
Target:
Research Areas:
PEX5-PEX14 PPI-IN-2 (compound 12) is a PEX14-PEX5 protein-protein interaction (PPI) inhibitor. PEX5-PEX14 PPI-IN-2 inhibits PEX14-PEX5 PPI with EC50 values of 5 and 17 µM in T. b. brucei and HepG2 cells, respectively. PEX5-PEX14 PPI-IN-2 can be used in the research of diseases related to trypanosome infection .
Cat. No.: HY-P3491
CAS No.: 2420483-82-3
Synonyms: Polyethylene glycol loxenatide; PEX 168
Target:
GCGR PI3K Akt Reactive Oxygen Species (ROS) Autophagy Interleukin Related Sirtuin AMPK Apoptosis
Research Areas:
Cardiovascular Disease Metabolic Disease Inflammation/Immunology
Cat. No.: HY-155530
CAS No.: 3052256-26-2
PEX5-PEX14 PPI-IN-1 (Compound 8) is a PEX14-PEX5 PPI inhibitor. PEX5-PEX14 PPI-IN-1 disrupts the PEX5-TbPEX14 PPI with a Ki of 53 μM. PEX5-PEX14 PPI-IN-1 inhibits the bloodstream form of T. b. brucei (EC50: 5 μM) .
Cat. No.: HY-155869
CAS No.: 79671-09-3
Synonyms: 5-Fluoro-2′-deoxycytidine 5′-triphosphate
Target:
Research Areas:
5-fluoro-dCTP is a fluorinated pyrimidine dNTP that can be used as a substrate for the incorporation of fluorine modification into specific DNA sequences by primer extension (PEX) catalyzed by Pwo polymerase .
Cat. No.: HY-175517
PEX5-PEX14 PPI-IN-3 (Compound 7) is an inhibitor of the PEX5-PEX14 protein-protein interaction (PPI) with an EC50 of 95 μM. PEX5-PEX14 PPI-IN-3 has an EC50 of 7.2 μM against Trypanosoma brucei (T. brucei). PEX5-PEX14 PPI-IN-3 exhibits low cytotoxicity towards HepG2 cells and possesses antiparasitic activity .
Cat. No.: HY-RS10339
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PEX1 Human Pre-designed siRNA Set A contains three designed siRNAs for PEX1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS10340
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PEX10 Human Pre-designed siRNA Set A contains three designed siRNAs for PEX10 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS10343
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PEX12 Human Pre-designed siRNA Set A contains three designed siRNAs for PEX12 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS10344
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PEX13 Human Pre-designed siRNA Set A contains three designed siRNAs for PEX13 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS10345
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PEX14 Human Pre-designed siRNA Set A contains three designed siRNAs for PEX14 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS10347
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PEX19 Human Pre-designed siRNA Set A contains three designed siRNAs for PEX19 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS10348
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PEX2 Human Pre-designed siRNA Set A contains three designed siRNAs for PEX2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS10349
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PEX26 Human Pre-designed siRNA Set A contains three designed siRNAs for PEX26 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS10350
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PEX3 Human Pre-designed siRNA Set A contains three designed siRNAs for PEX3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS10351
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Research Areas:
PEX5 Human Pre-designed siRNA Set A contains three designed siRNAs for PEX5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS10353
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PEX6 Human Pre-designed siRNA Set A contains three designed siRNAs for PEX6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS10354
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PEX7 Human Pre-designed siRNA Set A contains three designed siRNAs for PEX7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS20079
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Research Areas:
Pex19 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pex19 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS21406
Target:
Research Areas:
Pex2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pex2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
