21 Results for "

PKA Substrate

" in MedChemExpress (MCE) Product Catalog:
Products (21)

21 Results for "PKA Substrate" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-N1420
CAS No.: 3615-41-6
Synonyms: L-Rhamnose
Rhamnose (L-Rhamnose ) is an orally active deoxysugar. Rhamnose can inhibit levels of pro-inflammatory interleukin and matrix metalloproteinases (MMPs) in skin aging models. Rhamnose can promote the phosphorylation levels of PKA substrates and HSL in SVF-derived adipocytes, stimulating PKA signaling. Rhamnose can act against obesity in mice by stimulating fat dopamine receptors and inducing thermogenesis. Rhamnose shows anti-aging effects. Rhamnose monohydrate can be used in the study of Ehrlich’s solid tumors and sarcomas .
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1
1 Cited Publications
Cat. No.: HY-N1420A
CAS No.: 10030-85-0
Synonyms: L-Rhamnose monohydrate
Rhamnose monohydrate (L-Rhamnose monohydrate) is an orally active deoxysugar. Rhamnose monohydrate can inhibit levels of pro-inflammatory interleukin and matrix metalloproteinases (MMPs) in skin aging models. Rhamnose can promote the phosphorylation levels of PKA substrates and HSL in SVF-derived adipocytes, stimulating PKA signaling. Rhamnose monohydrate can act against obesity in mice by stimulating fat dopamine receptors and inducing thermogenesis. Rhamnose monohydrate shows anti-aging effects. Rhamnose monohydrate can be used in the study of Ehrlich’s solid tumors and sarcomas .
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1
1 Cited Publications
Cat. No.: HY-P0248
CAS No.: 65189-71-1
Target:  

PKA

Research Areas:  

Metabolic Disease

Kemptide is a synthetic heptapeptide that acts as a specific substrate for cAMP-dependent protein kinase (PKA).
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1
1 Cited Publications
Cat. No.: HY-115732
CAS No.: 179985-52-5
Purity:  99.82%
Target:  

PKA

Research Areas:  

Inflammation/Immunology

PKA-IN-1 is a potent and selective cyclic AMP-dependent protein kinase (PKA) catalytic subunit (cAK) inhibitor with an IC50 of 0.03 μM. PKA-IN-1 inhibits cAK in a fashion that is competitive with respect to ATP as substrate .
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1
1 Cited Publications
Cat. No.: HY-P1597
CAS No.: 86555-35-3
Target:  

PKA PKC

Research Areas:  

Cancer

Malantide is a synthetic dodecapeptide derived from the site phosphorylated by cAMP-dependent protein kinase (PKA) on the β-subunit of phosphorylase kinase. Malantide is a highly specific substrate for PKA with a Km of 15 μM and shows protein inhibitor (PKI) inhibition >90% substrate phosphorylation in various rat tissue extracts . Malantide is also an efficient substrate for PKC with a Km of 16 μM .
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Cat. No.: HY-P10602
CAS No.: 103659-06-9
Synonyms: RII phosphopeptide
Target:  

PKA

Research Areas:  

Others

PKA Regulatory Subunit II Substrate (RII phosphopeptide) is a tool peptide derived from the regulatory subunit Type II (RII) of cyclic AMP-dependent protein kinase (PKA). PKA Regulatory Subunit II Substrate is commonly used to mimic the phosphorylation of protein kinases and as a specific substrate for protein phosphatases to assess the activities of these enzymes .
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Cat. No.: HY-P1595
CAS No.: 149155-45-3
Target:  

PKA PKC

Research Areas:  

Metabolic Disease

CREBtide is a CREB (cAMP response element binding protein)-like peptide. CREBtide, a synthetic 13 amino acid peptide, has been reported as a PKA and PKC substrate.
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Cat. No.: HY-P4331
CAS No.: 113865-85-3
Research Areas:  

Cardiovascular Disease

Boc-Gln-Gly-Arg-AMC is a fluorogenic substrate for kallikrein (PKa), coagulation factor XIIa (FXIIa) and coagulation factor XIa (FXIa). Boc-Gln-Gly-Arg-AMC enables fluorescence-based activity assays for PKa, FXIIa and FXIa .
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Cat. No.: HY-N1420AR
CAS No.: 10030-85-0
Synonyms: L-Rhamnose monohydrate (Standard)
Rhamnose monohydrate (Standard) is the analytical standard of Rhamnose monohydrate (HY-N1420A). Rhamnose monohydrate (L-Rhamnose monohydrate) is an orally active deoxysugar. Rhamnose monohydrate can inhibit levels of pro-inflammatory interleukin and matrix metalloproteinases (MMPs) in skin aging models. Rhamnose can promote the phosphorylation levels of PKA substrates and HSL in SVF-derived adipocytes, stimulating PKA signaling. Rhamnose monohydrate can act against obesity in mice by stimulating fat dopamine receptors and inducing thermogenesis. Rhamnose monohydrate shows anti-aging effects. Rhamnose monohydrate can be used in the study of Ehrlich’s solid tumors and sarcomas .
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Cat. No.: HY-137325A
CAS No.: 301334-89-4
Target:  

Calcium Channel

Research Areas:  

Metabolic Disease

2-Chloro-ATP sodium (2-Chloro ATP) is an adenine nucleotide and an analog of ATP. It is an antagonist of the purinergic P2Y1 receptor and inhibits intracellular calcium mobilization induced by ADP (HY-W010918) in Jurkat cells expressing the human receptor (Ki=2.3 μM). 2-Chloro-ATP sodium is an agonist of the purinergic P2X receptor and induces inward currents in HEK293 cells expressing human bladder smooth muscle or rat PC12 forms of the receptor (EC50=0.5 and 2.5 μM). 2-Chloro-ATP sodium induces relaxation of precontracted guinea pig cecal strips in a concentration-dependent manner. 2-Chloro-ATP sodium has been used to study the substrate specificity of cyclic nucleotide-dependent protein kinases such as protein kinase A (PKA) and PKG.
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Cat. No.: HY-121197
CAS No.: 63590-19-2
Synonyms: Ophiocordin; Azepinostatin
Target:  

MARCKS PKA PKC

Balanol (Ophiocordin; Azepinostatin) is a potent and ATP competitive PKC/PKA inhibitor against human PKC isozymes α, β-I, β-II, γ, δ, ε, η (IC50s=4-9 nM) and ζ (IC50=150 nM). Balanol also blocks the phosphorylation of cyclic AMP response element-binding protein (CREB) and myristoylated alanine-rich C kinase substrate (MARCKS). Balanol can be isolated from the fungus Verticillium balanoides .
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Cat. No.: HY-P10098
CAS No.: 121932-31-8
Target:  

PKA

Research Areas:  

Cancer

PKA Substrate is a potent and selective substrate peptide of PKA that can be used to detect PKA activity .
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Cat. No.: HY-P0228A
Target:  

PKA

Research Areas:  

Metabolic Disease

PKA RII peptide TFA is a PKA substrate that, after being phosphorylated at the serine residue, can be used for the detection of calcineurin activity .
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Cat. No.: HY-P3770
CAS No.: 93511-94-5
Target:  

PKC

Research Areas:  

Others

Phosphate acceptor peptide is a substrate for cAMP-dependent protein kinase (PKA). phosphate acceptor peptide is also a weak PKC inhibitor .
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Cat. No.: HY-P0228
CAS No.: 113873-67-9
Target:  

PKA

Research Areas:  

Neurological Disease

PKA RII peptide is a PKA substrate that, after being phosphorylated at the serine residue, can be used for the detection of calcineurin activity .
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Cat. No.: HY-P0248F
CAS No.: 1161072-61-2
Target:  

PKA Fluorescent Dye

Research Areas:  

Metabolic Disease

Kemptide, 5-FAM labeled is a 5-FAM labeled Kemptide (HY-P0248). Kemptide is a phosphate acceptor peptide that serves as a synthetic substrate for PKA (Km = 16 μM). The corresponding fluorescent and biotinylated peptides are also proven to be good substrates for PKA.
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Cat. No.: HY-P3745
CAS No.: 65189-70-0
Target:  

PKA

Research Areas:  

Others

H1-7 (histone H1 phosphorylation site), PKA Substrate, a synthetic polypeptide, can be used as PKA substrate .
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Cat. No.: HY-P3920
CAS No.: 309247-46-9
Target:  

PKA

Research Areas:  

Cancer

Cys-Kemptide is a cysteine-terminated substrate peptide that can used to measure protein kinase A (PKA) activity .
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Cat. No.: HY-P1597A
Target:  

PKA PKC

Research Areas:  

Cancer

Malantide TFA is a synthetic dodecapeptide derived from the site phosphorylated by cAMP-dependent protein kinase (PKA) on the β-subunit of phosphorylase kinase. Malantide TFA is a highly specific substrate for PKA with a Km of 15 μM and shows protein inhibitor (PKI) inhibition >90% substrate phosphorylation in various rat tissue extracts . Malantide TFA is also an efficient substrate for PKC with a Km of 16 μM .
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Cat. No.: HY-P5526
Target:  

Casein Kinase

Research Areas:  

Others

CCK1-specific peptide substrate is a biological active peptide. (This peptide sequence is based on rabbit muscle glycogen synthase with Ser7 phosphorylated. It is a peptide substrate for Casein Kinase I (CK1). CK1 phosphorylates Ser10. Ser7 is phosphorylated by PKA in vivo.)
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