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PTP‐1B

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (1) Acyltransferase (1) Akt (5) Aldose Reductase (2) AMPK (1) Amylases (2) Amyloid-β (1) Antibiotic (1) Apoptosis (14) Atg8/LC3 (1) Autophagy (2) Bacterial (5) Bcl-2 Family (1) Beta-secretase (1) Calcium Channel (1) Caspase (1) CDK (1) Cholinesterase (ChE) (1) Dipeptidyl Peptidase (1) Drug Intermediate (1) EGFR (2) Endogenous Metabolite (2) Enterovirus (1) Environmental Pollutants (2) ERK (5) Fluorescent Dye (1) Fungal (3) GLUT (1) Glycosidase (9) Heme Oxygenase (HO) (1) HIV (1) HIV Protease (1) IFNAR (2) IKK (1) Insulin Receptor (2) Interleukin Related (5) JAK (2) JNK (4) Keap1-Nrf2 (1) Ligands for Target Protein for PROTAC (1) Lipoxygenase (1) MMP (3) Monoamine Oxidase (1) mTOR (3) NF-κB (8) NO Synthase (3) P-glycoprotein (1) p38 MAPK (8) Parasite (2) PARP (1) PD-1/PD-L1 (1) PERK (1) PGE synthase (2) Phosphatase (140) PI3K (1) PPAR (3) Pregnane X Receptor (PXR) (1) PROTAC Linkers (1) PROTACs (3) PTEN (3) Reactive Oxygen Species (ROS) (4) Reference Standards (7) SARS-CoV (1) SHP1 (5) SHP2 (9) Small Interfering RNA (siRNA) (3) STAT (7) Survivin (1) TGF-beta/Smad (1) Tie (3) TMV (1) Toll-like Receptor (TLR) (2) Tyrosinase (3) Wnt (2) β-catenin (2)
By Research Areas:	Cancer (50) Cardiovascular Disease (7) Endocrinology (6) Infection (11) Inflammation/Immunology (29) Metabolic Disease (82) Neurological Disease (11)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (1) Phospholipids (1) Human Pre-designed siRNA Sets (1) Antisense Oligonucleotides (2) siRNAs (3)

157

Inhibitors & Agonists

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-12219A

MSI-1436 lactate 5+ Cited Publications Trodusquemine lactate; Aminosterol-1436 lactate	Phosphatase	Endocrinology
MSI-1436 lactate is a selective, non-competitive inhibitor of the enzyme protein-tyrosine phosphatase 1B (PTP1B), with an IC₅₀ of 1 μM, 200-fold preference over TCPTP (IC₅₀ of 224 μM).

HY-N1549

Prunin 4 Publications Verification Naringenin 7-0-glucoside	Enterovirus Phosphatase	Infection Metabolic Disease
Prunin is a potent inhibitor of human enterovirus A71 (HEVA71). Prunin shows strong inhibitory activity against protein tyrosine phosphatase 1B (PTP1B), with an IC₅₀ of 5.5 μM ^[1] .

HY-10704

PTP1B-IN-1 5 Publications Verification PTP1B inhibitor	Phosphatase NF-κB	Neurological Disease Inflammation/Immunology
PTP1B-IN-1 (Compound 7a) is a small molecule inhibitor of *PTP1B* with an IC₅₀ value of 1.6 mM. It is often used as the mother core for derivatives of analogues ^[1] .

HY-121515

DPM-1001	Phosphatase	Metabolic Disease
DPM-1001 is a potent, specific, orally active and non-competitive inhibitor of protein-tyrosine phosphatase (PTP1B) with an IC₅₀ of 100 nM. DPM-1001 is an analog of the specific PTP1B inhibitor MSI-1436. DPM-1001 has anti-diabetic property ^[1].

HY-112368

PHPS1 5 Publications Verification	SHP2 SHP1 Phosphatase	Cardiovascular Disease Cancer
PHPS1 is a potent and selective Shp2 inhibitor with K_is of 0.73, 5.8, 10.7, 5.8, and 0.47 μM for Shp2, Shp2-R362K, Shp1, PTP1B, and PTP1B-Q, respectively ^[1].

HY-100462

PTP1B-IN-2 4 Publications Verification	Phosphatase	Metabolic Disease
PTP1B-IN-2 is a potent protein tyrosine phosphatase 1B (PTP1B) inhibitor with an IC₅₀ of 50 nM.

HY-15756

PTP1B-IN-4 1 Publications Verification	Phosphatase	Metabolic Disease
PTP1B-IN-4 is a non-competitive allosteric inhibitor of the protein tyrosine phosphatase *PTP1B, with an IC₅₀* of 8 μM. PTP1B-IN-4 is potentail for the research of obesity and diabetes ^[1] .

HY-N0374

Licochalcone C 4 Publications Verification	Glycosidase	Metabolic Disease
Licochalcone C could inhibit α-glucosidase, with IC₅₀s of <100 nM and 92.43 μM for α-glucosidase and protein tyrosine phosphatase 1B (PTP1B), respectively.

HY-123966

MY33-3	Phosphatase	Neurological Disease
MY33-3 is a potent and selective inhibitor of receptor protein tyrosine phosphatase (RPTP)β/ζ, with an IC₅₀ of ~0.1 μM. MY33-3 also inhibits *PTP-1B* (IC₅₀ ~0.7 μM). MY33-3 can reduce ethanol consumption and alleviate Sevoflurane-induced neuroinflammation and cognitive dysfunction ^[1] .

HY-12219

MSI-1436 Trodusquemine; Aminosterol-1436	Phosphatase	Endocrinology
MSI-1436 is a selective, non-competitive inhibitor of the enzyme protein-tyrosine phosphatase 1B (PTP1B), with an IC₅₀ of appr 1 μM, 200-fold preference over TCPTP (IC₅₀, 224 μM).

HY-101964

SPI-112 1 Publications Verification	SHP2 Phosphatase	Cancer
SPI-112 is a potent, selective and competitive SHP2 (PTPN11) inhibitor with IC₅₀s of 1 μM, 18.3 μM and 14.5 μM for SHP2, protein tyrosine phosphatase (PTP) and PTP1B, respectively ^[1] .

HY-12312

TCS 401 2 Publications Verification	Phosphatase	Metabolic Disease
TCS 401 is a selective inhibitor of protein tyrosine phosphatase 1B (PTP1B).

HY-15133

PTP1B-IN-3	Phosphatase	Metabolic Disease Cancer
PTP1B-IN-3 is a potent and orally active *PTP1B* inhibitor with IC₅₀s of 120 nM for both *PTP1B* and TCPTP. PTP1B-IN-3 has antidiabetic and anticancer effects ^[1] .

HY-164864

*DU-14 (PTP1B/TC-PTP* PROTAC)**	PROTACs STAT	Cancer
DU-14 (PTP1B/TC-PTP PROTAC) is a potent and selective *PTP1B* and *TC-PTP* dual PROTAC degrader. DU-14 (PTP1B/TC-PTP PROTAC) has the IC₅₀ for *PTP1B* and *TC-PTP* phosphatase activity of 24.2 nM and 30.1 nM, respectively. DU-14 (PTP1B/TC-PTP PROTAC) enhances IFN-γ signaling, promotes T cell activation, and has anti-tumor activity. (Pink: PTP1B/TC-PTP inhibitor (HY-171027); Black: Linker (HY-W340290); Blue: E3 ligand (HY-112078)) ^[1].

HY-153446

Tegeprotafib PTPN2/1-IN-1	Phosphatase	Cancer
Tegeprotafib (PTPN2/1-IN-1) (Compound 124) is an orally active PTPN1 and PTPN2 inhibitor with IC₅₀s of 4.4 nM and 1-10 nM against PTPN2 and *PTP1B*, respectively ^[1].

HY-N9326

Uralenol	Phosphatase	Metabolic Disease
Uralenol is a natural *PTP1B* inhibitor (IC₅₀=21. 5 μM) from Broussonetia papyrifera. PTP1B have been shown to play a major role in the dephosphorylation of the insulin receptor in many cellular and biochemical studies ^[1].

HY-19383

Ertiprotafib 2 Publications Verification PTP 112	Phosphatase IKK PPAR	Metabolic Disease
Ertiprotafib is an inhibitor of PTP1B, IkB kinase β (IKK-β), and a dual PPARα and PPARβ agonist, with an IC₅₀ of 1.6 μM for PTP1B, 400 nM for IKK-β, an EC₅₀ of ~1 μM for PPARα/PPARβ.

HY-N1789

Kaempferol-7,4'-dimethyl ether	Phosphatase Others	Others
Kaempferol-7,4'-dimethyl ether is a *PTP1B* inhibitor, and also can inhibit the production of NO. Kaempferol-7,4'-dimethyl ether shows the inhibition rate of 46.1% at 100 μM. Kaempferol-7,4'-dimethyl ether inhibits *PTP1B* activity with IC50 value of 16.92 μM ^[1] .

HY-161321

PTP1B-IN-24	Phosphatase Insulin Receptor Akt	Metabolic Disease
PTP1B-IN-24 (Compound 9) is a reversible *PTP1B* inhibitor with an IC₅₀ value of 1.4 μM, and PTP1B-IN-24 can enhance the thermal stability of *PTP1B. PTP1B-IN-24* can restore PA- (HY-N0830) induced insulin resistance by increasing the phosphorylation levels of *IRS1* and AKT ^[1].

HY-N4185

Licoflavone A 3 Publications Verification	Phosphatase	Neurological Disease
Licoflavone A is a flavonoid isolated from the roots of Glycyrrhiza uralensis, inhibits protein tyrosine phosphatase-1B (PTP1B), with an IC₅₀ of 54.5 μM ^[1].

HY-158381

*PROTAC PTP1B* degrader 1**	PROTACs Phosphatase	Metabolic Disease
PROTAC PTP1B degrader 1 (compound 75) is a CRBN-based *PTP1B* PROTAC degrader, with DC₅₀ values of 0.2 μM (48 h) and 0.05 μM (72 h) (Red: PTP1B ligand Oleanolic acid (HY-N0156); Black: linker; Blue: CRBN ligand) ^[1].

HY-121515A

DPM-1001 trihydrochloride	Phosphatase	Metabolic Disease
DPM-1001 trihydrochloride is a potent, specific, orally active and non-competitive inhibitor of protein-tyrosine phosphatase (PTP1B) with an IC₅₀ of 100 nM. DPM-1001 trihydrochloride is an analog of the specific PTP1B inhibitor MSI-1436. DPM-1001 trihydrochloride has anti-diabetic property ^[1].

HY-115605

CN009543V	EGFR p38 MAPK ERK Phosphatase	Cancer
CN009543V is an epidermal growth factor receptor (EGFR) agonist. CN009543V enhances tyrosine phosphorylation of EGFR at Tyr1068 and Tyr1173, thereby activating the MAPK/ERK cascade. CN009543V inhibits the activity of *PTP-1B* in MDA MB468 cells. CN009543V can be used in cancer research ^[1].

HY-19779

JTT 551	Phosphatase	Metabolic Disease
JTT 551 is selective a protein tyrosine phosphatase 1B (PTP1B) inhibitor, with K_is of 0.22 μM and 9.3 μM for PTP1B and TCPTP (T-cell protein tyrosine phosphatase), respectively; JTT 551 can be used in the research of type 2 diabetes mellitus.

HY-N6650

Isotanshinone IIA	Phosphatase	Metabolic Disease
Isotanshinone IIA, an abietane-type diterpene metabolite, could non-competitively inhibit Protein Tyrosine Phosphatase 1B (PTP1B) activity with an IC₅₀ 0f 11.4 μM.

HY-N10002

Caffeoyltryptophan 1 Publications Verification	Phosphatase Glycosidase	Metabolic Disease
Caffeoyltryptophan is a competitive *PTP1B* inhibitor, with an IC₅₀ of 16.99 μM. Caffeoyltryptophan can also inhibit α-glucosidase, linoleic acid peroxidation and haemolysis. Caffeoyltryptophan can be used for the research of type 2 diabetes ^[1].

HY-120901

II-B08	SHP2 SHP1	Cancer
II-B08 is a reversible and noncompetitive SHP2 inhibitor (IC₅₀: 5.5 μM, 15.7, 14.3 μM for SHP2, SHP1, PTP1B). II-B08 can be used for cancer research ^[1].

HY-N2111

Momordicoside A	Phosphatase	Metabolic Disease
Momordicoside A is isolated from Momordica charantia L. Momordicoside A has the inhibitory effect on protein tyrosine phosphatase (PTP1B) ^[1].

HY-153018

PTP1B-IN-22	Phosphatase	Metabolic Disease
PTP1B-IN-22, a ZINC02765569 derivative, is a potent protein tyrosine phosphatase 1B (PTP1B) inhibitor. PTP1B-IN-22 has PTP1B inhibition and glucose uptake in skeletal muscle L6 myotubes ^[1].

HY-108196

PTP1B-IN-15	Phosphatase	Endocrinology
PTP1B-IN-15 is a potent and selective inhibitor of protein tyrosine phosphatase 1B (PTP1B). PTP1B-IN-15 has the potential for the research of type II diabetes and obesity ^[1].

HY-111469

CPT-157633 1 Publications Verification	Phosphatase	Metabolic Disease
CPT-157633, a difluoro-phosphonomethyl phenylalanine derivative, and is a *PTP1B* inhibitor. CPT-157633 prevents binge drinking-induced glucose intolerance ^[1].

HY-163463

PTP1B-IN-25	Phosphatase Fungal HIV Bacterial	Infection Metabolic Disease
PTP1B-IN-25 (Compound 19) is a *PTP1B* inhibitor with remarkable antiviral, antibacterial, and antidiabetic activities. PTP1B-IN-25 has IC₅₀ values of 0.37 μM, 8.6 μM, 3.7 μM, and 29 μM against *PTP1B, HIV, α-Glucosidase, and methicillin-resistant Staphylococcus aureus* (MRSA) respectively ^[1].

HY-N4143

Cyanidin 3-arabinoside	Phosphatase	Metabolic Disease
Cyanidin 3-arabinoside is a selective and reversible protein tyrosine phosphatase 1B (PTP1B) inhibitor, with an IC₅₀ of 8.91 μM. Cyanidin 3-arabinoside is potential for the research of type 2 diabetes ^[1].

HY-N1230

Sophoraisoflavone A Allolicoisoflavone B	Phosphatase	Inflammation/Immunology
Sophoraisoflavone A (Allolicoisoflavone B) is a nature product that could be isolated from Glycyrrhiza inflate. Sophoraisoflavone A is a potent protein tyrosine phosphatase 1B (PTP1B) inhibitor with an IC₅₀ value of 0.80 μM. Sophoraisoflavone A can be used in research of inflammation ^[1].

HY-162479

PTP1B-IN-26	Phosphatase Amyloid-β	Metabolic Disease
PTP1B-IN-26 (Compound 7a) is a derivative of phenylthiosemicarbazide‐phenoxy‐1,2,3‐triazole‐N‐phenylacetamide. PTP1B-IN-26 is an inhibitor of protein tyrosine phosphatase 1B (PTP-1B). PTP1B-IN-26 is a competitive inhibitor. PTP1B-IN-26 can be used to research in type 2 diabetes ^[1].

HY-162480

PTP1B-IN-27	Glycosidase Phosphatase	Endocrinology
PTP1B-IN-27 (Compound 7i) is an inhibitor of protein tyrosine phosphatase 1-B (PTP‐1B)(IC₅₀=8.2 µM). PTP1B-IN-27 also inhibits α-Glucosidase (IC₅₀=120 µM) and shows competitive inhibition (K_i=118 µM) ^[1].

HY-160550

DPM-1003	Phosphatase	Inflammation/Immunology
DPM-1003 is a *PTP1B* conformational inhibitor that targets the non-catalytic, disordered segment at the C-terminus of the *PTP1B* protein, showing improvement in lung inflammation in mice ^[1].

HY-156608

Anticancer agent 144	Phosphatase	Cancer
Anticancer agent 144 (compound 444) is a dual *PTPN2/PTP1B* inhibitor with IC₅₀ values <2.5 nM. Anticancer agent 144 can be used in cancer research ^[1].

HY-179285

PTP1B-IN-32	Phosphatase	Metabolic Disease
PTP1B-IN-32 (Compound 5G) is an uncompetitive *PTP1B* inhibitor, with a K_i value of 0.72 μM. PTP1B-IN-32 enhances insulin sensitivity. PTP1B-IN-32 can be used in the research of diabetes ^[1].

HY-15133A

PTP1B-IN-3 diammonium	Phosphatase	Metabolic Disease Cancer
PTP1B-IN-3 diammonium is a potent and orally active *PTP1B* inhibitor with IC₅₀s of 120 nM for both *PTP1B* and TCPTP. PTP1B-IN-3 diammonium has antidiabetic and anticancer effects ^[1] .

HY-159694

*IONIS PTP1BRx* ISIS 404173	Phosphatase	Metabolic Disease
IONIS PTP1BRx (ISIS 404173) is an antisense inhibitor of protein tyrosine phosphatase 1B (PTP-1B). IONIS PTP1BRx shows antidiabetic activity, and can be used for the study of insulin resistance and type 2 diabetes mellitus associated with obesity ^[1].

HY-174250

PTP1B-IN-31	Phosphatase	Inflammation/Immunology Cancer
PTP1B-IN-31 (Compound (S,S)-3ak) is a *PTP1B* inhibitor with an IC₅₀ of 0.81 μM. PTP1B-IN-31 can inhibit the growth of tumor cells in synergy with the cytokine IFNγ. PTP1B-IN-31 can be used in cancer research ^[1].

HY-139641

PTP1B-IN-14	Phosphatase	Others
PTP1B-IN-14 is a selective *PTP1B* inhibitor (IC₅₀ = 0.72 μM) targeting the allosteric site.

HY-139640

PTP1B-IN-13	Phosphatase	Others
PTP1B-IN-13 is a selective *PTP1B* inhibitor targeting the allosteric site with an IC₅₀ value of 1.59 μM.

HY-144717

PTP1B-IN-18	Phosphatase	Metabolic Disease
PTP1B-IN-18 is an orally active complete mixed type protein tyrosine phosphatase 1B (PTP1B) inhibitor with a K_i of 35.2 μM. PTP1B-IN-18 can be used for type 2 diabetes research ^[1].

HY-144718

PTP1B-IN-17	Phosphatase	Metabolic Disease
PTP1B-IN-17 (Compound 45), a potential selective benzimidazole derivative, acts as a protein tyrosine phosphatase 1B (PTP1B) inhibitor with a K_i of 30.2 μM. PTP1B-IN-17 can be used for the research of type 2 diabetes.

HY-144713

PTP1B-IN-16	Phosphatase	Metabolic Disease
PTP1B-IN-16 (Compound 46), a potential selective benzimidazole derivative, acts as a protein tyrosine phosphatase 1B (PTP1B) inhibitor with a K_i of 12.6 μM. PTP1B-IN-16 can be used for the research of type 2 diabetes.

HY-144716

PTP1B-IN-19	Phosphatase	Metabolic Disease
PTP1B-IN-19 (Compound 43), a potential selective benzimidazole derivative, acts as a protein tyrosine phosphatase 1B (PTP1B) inhibitor with a K_i of 23.3 μM. PTP1B-IN-19 can be used for the research of type 2 diabetes.

HY-171027

PTP1B/TC-PTP IN-1	Ligands for Target Protein for PROTAC	Cancer
PTP1B/TC-PTP IN-1 is a *PTP1B* and *TC-PTP* dual inhibitor. PTP1B/TC-PTP IN-1 can be used as a target protein ligand for the synthesis of DU-14 (PTP1B/TC-PTP PROTAC) (HY-164864) ^[1].

HY-173034

PTP1B-IN-30	Phosphatase Apoptosis	Cancer
PTP1B-IN-30 (Compound 3j) is the inhibitor for *PTP1B* with an IC₅₀ of 0.51 µM. PTP1B-IN-30 inhibits the proliferation of cancer cell T47D with an IC₅₀ of 21.21 µM, arrests the cell cycle at S phase, and induces apoptosis in T47D ^[1].

Cat. No.	Product Name	Target	Research Area

HY-P1799

[pTyr5] EGFR (988-993)	Phosphatase	Others
[pTyr5] EGFR (988-993) is derived from the autophosphorylation site (Tyr992) of epidermal growth factor receptor (EGFR 988-993). [pTyr5] EGFR (988-993) is often complexed with the catalytically inactive protein-tyrosine phosphate 1B (PTP1B) ^[1].

HY-P1799A

[pTyr5] EGFR (988-993) TFA	Phosphatase	Others
[pTyr5] EGFR (988-993) TFA is derived from the autophosphorylation site (Tyr992) of epidermal growth factor receptor (EGFR 988-993). [pTyr5] EGFR (988-993) TFA is often complexed with the catalytically inactive protein-tyrosine phosphate 1B (PTP1B) ^[1].

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P73685

	PTP1B Protein, Human (His) 1 Publications Verification PTP-1B; PTPN1; Tyrosine-protein phosphatase non-receptor type 1	Human	E. coli
	PTP1B is an important tyrosine protein phosphatase that regulates the endoplasmic reticulum unfolded protein response by dephosphorylating EIF2AK3/PERK and inhibiting its kinase activity. It affects the signaling cascade induced by CKII and p60c-src, and may regulate the EFNA5-EPHA3 pathway, affecting cell reorganization. PTP1B Protein, Human (His) is the recombinant human-derived PTP1B protein, expressed by E. coli , with N-His labeled tag.

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Host:	Mouse (2) Rabbit (5)
Reactivity:	Human (7)
Application:	IHC-P (6) ICC/IF (5) IP (1) IHC-F (2) WB (7) FC (2) ELISA (2)
Isotype:	IgG (5) IgG1 (2)
Conjugation:	Non-conjugated (7)
Clonality:	Monoclonal (3) Monoclonal Antibody (1) Recombinant (3)
Modification:	Phosphorylated (2) Unmodified (2)

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HY-P84143

	PTP1B Antibody (YA3840) PTP1B	WB, IHC-P, ICC/IF, FC, ELISA	Human
	PTP1B Antibody (YA3840) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PTP1B.

HY-P84143A

	PTP1B Antibody (YA3840)(PBS only) PTP1B	WB, IHC-P, ICC/IF, FC, ELISA	Human
	PTP1B Antibody (YA3840) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PTP1B.

HY-P82031

	PTP1B Antibody (YA1776) PTPN1; PTP1B; Tyrosine-protein phosphatase non-receptor type 1; Protein-tyrosine phosphatase 1B; PTP-1B	WB, IHC-F, IHC-P, ICC/IF	Human
	PTP1B Antibody (YA1776) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PTP1B.

HY-P82031A

	PTP1B Antibody (YA1776)(PBS only) PTPN1; PTP1B; Tyrosine-protein phosphatase non-receptor type 1; Protein-tyrosine phosphatase 1B; PTP-1B	WB, IHC-F, IHC-P, ICC/IF	Human
	PTP1B Antibody (YA1776) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PTP1B.

HY-P81300A

	*Phospho-PTP1B* (Ser378) Antibody (YA1028)** PTPN1; PTP1B; Tyrosine-protein phosphatase non-receptor type 1; Protein-tyrosine phosphatase 1B; PTP-1B	WB, IHC-P	Human
	Phospho-PTP1B (Ser378) Antibody (YA1028) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-PTP1B (Ser378).

HY-P81300AA

	*Phospho-PTP1B* (Ser378) Antibody (YA1028)(PBS only)** PTPN1; PTP1B; Tyrosine-protein phosphatase non-receptor type 1; Protein-tyrosine phosphatase 1B; PTP-1B	WB, IHC-P	Human
	Phospho-PTP1B (Ser378) Antibody (YA1028) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-PTP1B (Ser378).

HY-P81300

	*Phospho-PTP1B* (Ser352) Antibody (YA1027)** PTPN1; PTP1B; Tyrosine-protein phosphatase non-receptor type 1; Protein-tyrosine phosphatase 1B; PTP-1B	WB, ICC/IF, IP	Human
	Phospho-PTP1B (Ser352) Antibody (YA1027) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-PTP1B (Ser352).

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Cat. No.	Product Name		Classification

HY-RS11415

PTPN1 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
PTPN1 Human Pre-designed siRNA Set A contains three designed siRNAs for PTPN1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-157673

1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine 16:1 PE		Phospholipids
1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine (16:1 PE) is a phosphatidylethanolamine that can enhance PP2A and *PTP1B* activities in malignant pleural mesothelioma cells. 1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine induces apoptosis of NCI-H28 malignant pleural mesothelioma cells ^[1].

HY-159694

*IONIS PTP1BRx* ISIS 404173		Antisense Oligonucleotides
IONIS PTP1BRx (ISIS 404173) is an antisense inhibitor of protein tyrosine phosphatase 1B (PTP-1B). IONIS PTP1BRx shows antidiabetic activity, and can be used for the study of insulin resistance and type 2 diabetes mellitus associated with obesity ^[1].

HY-159694A

*IONIS PTP1BRx sodium* ISIS 404173 sodium		Antisense Oligonucleotides
IONIS PTP1BRx (ISIS 404173) sodium is an antisense inhibitor of protein tyrosine phosphatase 1B (PTP-1B). IONIS PTP1BRx sodium shows antidiabetic activity, and can be used for the study of insulin resistance and type 2 diabetes mellitus associated with obesity ^[1].

HY-RS17205

Ptpn1 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Ptpn1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ptpn1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS23657

Ptpn1 Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Ptpn1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ptpn1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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PTP‐1B

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