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Pathways Recommended:	Protein Tyrosine Kinase/RTK

Results for "

Protein tyrosine phosphatase-1B

" in MedChemExpress (MCE) Product Catalog:

By Targets:	FAK (1) Phosphatase (54) 5-HT Receptor (1) Akt (1) Aldose Reductase (1) Amyloid-β (2) Apoptosis (2) Autophagy (2) Beclin1 (1) Beta-secretase (1) COX (1) Enterovirus (1) GLUT (1) Glycosidase (5) Interleukin Related (1) Keap1-Nrf2 (1) Lipoxygenase (1) Monoamine Oxidase (1) mTOR (1) NF-κB (1) p38 MAPK (1) PPAR (1) Pregnane X Receptor (PXR) (1) Reference Standards (3) Tau Protein (1) TMV (1) TNF Receptor (1)
By Research Areas:	Cancer (5) Cardiovascular Disease (1) Endocrinology (7) Infection (1) Inflammation/Immunology (7) Metabolic Disease (41) Neurological Disease (6)
Oligonucleotides:	Antisense Oligonucleotides (2)

Inhibitors & Agonists

Natural
Products

Recombinant Proteins

Antibodies

Oligonucleotides

Targets Recommended: Phosphatase Btk Syk SHP2 PhosTACs PTEN Pyk2 TNK1 Tyrosine Hydroxylase DYRK BRK FAK SHP1 FLT3 Anaplastic lymphoma kinase (ALK)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-12219A

MSI-1436 lactate Maximum Cited Publications 8 Publications Verification Trodusquemine lactate; Aminosterol-1436 lactate	Phosphatase	Endocrinology
MSI-1436 lactate is a selective, non-competitive inhibitor of the enzyme **protein-tyrosine phosphatase 1B (PTP1B), with an IC₅₀ of 1 μM, 200-fold preference over TCPTP (IC₅₀** of 224 μM).

HY-N1549

Prunin 4 Publications Verification Naringenin 7-0-glucoside	Enterovirus Phosphatase	Infection Metabolic Disease
Prunin is a potent inhibitor of human enterovirus A71 (HEVA71). Prunin shows strong inhibitory activity against protein tyrosine phosphatase 1B (PTP1B), with an IC₅₀ of 5.5 μM .

HY-100462

PTP1B-IN-2 4 Publications Verification	Phosphatase	Metabolic Disease
PTP1B-IN-2 is a potent protein tyrosine phosphatase 1B (PTP1B) inhibitor with an IC₅₀ of 50 nM.

HY-N0374

Licochalcone C 4 Publications Verification	Glycosidase	Metabolic Disease
Licochalcone C could inhibit α-glucosidase, with IC₅₀s of <100 nM and 92.43 μM for α-glucosidase and protein tyrosine phosphatase 1B (PTP1B), respectively.

HY-12219

MSI-1436 Trodusquemine; Aminosterol-1436	Phosphatase	Endocrinology
MSI-1436 is a selective, non-competitive inhibitor of the enzyme protein-tyrosine phosphatase 1B (PTP1B), with an IC₅₀ of appr 1 μM, 200-fold preference over TCPTP (IC₅₀, 224 μM).

HY-12312

TCS 401 2 Publications Verification	Phosphatase	Metabolic Disease
TCS 401 is a selective inhibitor of protein tyrosine phosphatase 1B (PTP1B).

HY-N4185

Licoflavone A 3 Publications Verification	Phosphatase	Neurological Disease
Licoflavone A is a flavonoid isolated from the roots of Glycyrrhiza uralensis, inhibits protein tyrosine phosphatase-1B (PTP1B), with an IC₅₀ of 54.5 μM .

HY-120327

KY-226 2 Publications Verification	Phosphatase	Neurological Disease Metabolic Disease
KY-226 is a potent, selective, orally active and allosteric protein tyrosine phosphatase 1B (PTP1B) inhibitor with an IC₅₀ of 0.25 μM, and without PPARγ agonist activity. KY-226 exerts anti-diabetic and anti-obesity effects by enhancing insulin and leptin signaling, respectively. KY-226 also protects neurons from cerebral ischemic injury .

HY-N2451

Aloe-emodin-8-O-β-D-glucopyranoside 1 Publications Verification	Phosphatase	Metabolic Disease Endocrinology
Aloe-emodin-8-O-β-D-glucopyranoside, a compound isolated from Saussrurea lappa, is a moderate inhibitor of *human protein* tyrosine phosphatase 1B (hPTP1B) with an IC₅₀** of 26.6 μM .

HY-121811

Pongamol Lanceolatin C	Glycosidase Phosphatase Interleukin Related TNF Receptor COX Beclin1 GLUT FAK Akt mTOR p38 MAPK Keap1-Nrf2 Apoptosis Amyloid-β Tau Protein Autophagy	Neurological Disease Inflammation/Immunology Cancer
Pongamol (Lanceolatin C) is an orally active flavonoid with an IC₅₀ of 75 μM and a K_i of 58 μM against PTPase-1B, and an IC₅₀ of 103.5 μM against intestinal α-Glycosidase. Pongamol reduces the release of IL‑1β, TNF‑α, COX‑2 and iNOS in cells, reverses the nuclear translocation of NF‑κB, and upregulates the levels of Beclin 1 and LC3 Ⅱ/LC3 Ⅰ. Pongamol promotes glucose uptake by increasing the level of GLUT4 on the surface of skeletal muscle cells. Pongamol inhibits epithelial-mesenchymal transition by suppressing the FAK/Akt-mTOR signaling pathway. Pongamol inhibits neuronal cytotoxicity, suppresses cell apoptosis and extends the lifespan of Caenorhabditis elegans by activating the MAPKs/Nrf2 signaling pathway. Pongamol exerts hypoglycemic effects in diabetic mouse models. Pongamol exhibits antibacterial activity. Pongamol alleviates oxidative stress, neuroinflammation, Aβ deposition and excessive phosphorylation of Tau Protein, and restores autophagy function in Alzheimer's disease mouse models by inhibiting the Akt/mTOR signaling pathway. Pongamol is applicable to research related to Alzheimer's disease, type 2 diabetes, non-small cell lung cancer and postprandial hyperglycemia .

HY-19779

JTT 551	Phosphatase	Metabolic Disease
JTT 551 is selective a protein tyrosine phosphatase 1B (PTP1B) inhibitor, with K_is of 0.22 μM and 9.3 μM for PTP1B and TCPTP (T-cell protein tyrosine phosphatase), respectively; JTT 551 can be used in the research of type 2 diabetes mellitus.

HY-N6650

Isotanshinone IIA	Phosphatase	Metabolic Disease
Isotanshinone IIA, an abietane-type diterpene metabolite, could non-competitively inhibit Protein Tyrosine Phosphatase 1B (PTP1B) activity with an IC₅₀ 0f 11.4 μM.

HY-117085

Lobaric acid	Phosphatase TMV Lipoxygenase	Cancer
Lobaric acid is a depsipeptide metabolite isolated from Stereocaulon lichen with antioxidant, antiproliferative, antiviral and enzyme inhibitory activities. Lobaric acid scavenges superoxide free radicals (IC₅₀=97.9 μM) and inhibits cancer cell proliferation (EC₅₀ of 15.2-63.9 μg/mL against leukemia, colorectal, gastric, breast, ovarian, prostate, pancreatic and lung cancer cell lines). Lobaric acid inhibits protein tyrosine phosphatase 1B (PTP1B; IC₅₀=0.87 μM for human recombinant enzyme) and 12(S)-HETE produced by 12(S)-lipoxygenase (IC₅₀=28.5 μM). Lobaric acid (250 μM) also reduced pathological changes in tobacco leaves infected with tobacco mosaic virus (TMV).

HY-N4143

Cyanidin 3-arabinoside	Phosphatase	Metabolic Disease
Cyanidin 3-arabinoside is a selective and reversible protein tyrosine phosphatase 1B (PTP1B) inhibitor, with an IC₅₀ of 8.91 μM. Cyanidin 3-arabinoside is potential for the research of type 2 diabetes .

HY-N1230

Sophoraisoflavone A Allolicoisoflavone B	Phosphatase	Inflammation/Immunology
Sophoraisoflavone A (Allolicoisoflavone B) is a nature product that could be isolated from Glycyrrhiza inflate. Sophoraisoflavone A is a potent protein tyrosine phosphatase 1B (PTP1B) inhibitor with an IC₅₀ value of 0.80 μM. Sophoraisoflavone A can be used in research of inflammation .

HY-N3734

Deoxyneocryptotanshinone	Beta-secretase Phosphatase	Neurological Disease
Deoxyneocryptotanshinone, a natural tanshinone, is a high affinity BACE1 (Beta-secretase) inhibitor with an IC₅₀ value of 11.53 μM. Deoxyneocryptotanshinone shows a promising dose-dependent inhibition of protein tyrosine phosphatase 1B (PTP1B) with an IC₅₀ value of 133.5 μM. Deoxyneocryptotanshinone can be used for Alzheimer's disease research .

HY-N16588

cis-Emodin-physcion bianthrone	Phosphatase	Metabolic Disease
cis-Emodin-physcion bianthrone is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B), with an IC₅₀ value of 7.29 μM. cis-Emodin-physcion bianthrone can be used for research on type 2 diabetes .

HY-N8200

Cassiaside B2	Phosphatase Monoamine Oxidase 5-HT Receptor	Inflammation/Immunology
Cassiaside B2 is a protein tyrosine phosphatase 1B (PTP1B) and human monoamine oxidase A (hMAO-A) inhibitor. Cassiaside B2 possesses antiallergic and is a 5-HT2C receptor agonist . ..

HY-108196

PTP1B-IN-15	Phosphatase	Endocrinology
PTP1B-IN-15 is a potent and selective inhibitor of protein tyrosine phosphatase 1B (PTP1B). PTP1B-IN-15 has the potential for the research of type II diabetes and obesity .

HY-128978

(E,E)-RAMB4	Phosphatase	Metabolic Disease
(E,E)-RAMB4 is a potent and selective *potent protein* tyrosine phosphatase-1B (PTP1B)** inhibitor extracted from patent CN103626692A, example 1 .

HY-159694

IONIS PTP1BRx ISIS 404173	Phosphatase	Metabolic Disease
IONIS PTP1BRx (ISIS 404173) is an antisense inhibitor of protein tyrosine phosphatase 1B (PTP-1B). IONIS PTP1BRx shows antidiabetic activity, and can be used for the study of insulin resistance and type 2 diabetes mellitus associated with obesity .

HY-153018

PTP1B-IN-22	Phosphatase	Metabolic Disease
PTP1B-IN-22, a ZINC02765569 derivative, is a potent protein tyrosine phosphatase 1B (PTP1B) inhibitor. PTP1B-IN-22 has PTP1B inhibition and glucose uptake in skeletal muscle L6 myotubes .

HY-124896

Bonannione A 6-Geranylnaringenin; Mimulone	Phosphatase Apoptosis Autophagy	Inflammation/Immunology Cancer
Bonannione A (6-Geranylnaringenin; Mimulone), a prenylflavonoid, is an orally active and potent protein tyrosine phosphatase 1B (PTP1B) inhibitor with an IC₅₀ of 14 µM. Bonannione A triggers caspase-dependent apoptosis. Bonannione A induces autophagy through p53-mediated AMPK/mTOR pathway. Bonannione A shows anti-inflammatory, antiradical and anti-cancer activity .

HY-12312A

TCS 401 free base	Phosphatase	Metabolic Disease
TCS 401 free base is a selective inhibitor of protein tyrosine phosphatase 1B (PTP1B).

HY-N3267

Methyl pseudolarate B	Phosphatase	Metabolic Disease
Methyl pseudolarate B, a natural diterpenoid, is a protein tyrosine phosphatase 1B (PTP1B) (Phosphatase) inhibitor with an IC₅₀ value of 10.9 μM .

HY-N12736

Dehydrodanshenol A	Phosphatase	Metabolic Disease
Dehydrodanshenol A is a non-competitive inhibitor of Protein tyrosine phosphatase 1B (PTP1B), with an IC₅₀ value of 8.5 μM. Dehydrodanshenol A can be used in diabetes-related research .

HY-N15308

Kanjone	Phosphatase	Neurological Disease Metabolic Disease
Kanjone is a compound found in Millettia peguensis and can be used for the synthesis of protein tyrosine phosphatase 1B (PTP1B) inhibitors. Kanjone holds promise for research in the fields of diabetes and neurological disorders .

HY-135564B

(Rac)-RK-682	Phosphatase	Cancer
(Rac)-RK-682, a racemate of RK-682, is a protein tyrosine phosphatases (PTPases) inhibitor. (Rac)-RK-682 inhibits protein tyrosine phosphatase 1B (PTP-1B), low molecular weight protein tyrosine phosphatases (LMW-PTP), and cell division cycle 25B (CDC-25B) with IC₅₀s of 8.6 μM, 12.4 μM, and 0.7 μM, respectively .

HY-N10064

Ficusonolide	Others	Metabolic Disease
Ficusonolide has significant antidiabetic activity with a possible mechanism of interaction with dipeptidyl peptidase-IV (DPP-IV), protein tyrosine phosphatase 1B (PTP-1B), α-glucosidase, and α-amylase.

HY-N10648

PTP1B-IN-20	Phosphatase	Metabolic Disease
PTP1B-IN-20 is a selective inhibitor of **protein tyrosine phosphatase 1B (PTP1B; IC₅₀*=1.05 μM) over the highly homologous T-cell protein* tyrosine phosphatase (TCPTP; IC₅₀=78.0 μM), which is a key target for type 2 diabetes inhibition .

HY-N16508

3-Hydroxyphloridzin 3-Hydroxyphlorizin	Phosphatase	Metabolic Disease
3-Hydroxyphloridzin (3-Hydroxyphlorizin) is a protein tyrosine phosphatase 1B (PTP1B) inhibitor. 3-Hydroxyphloridzin modulates insulin receptor phosphorylation levels. 3-Hydroxyphloridzin is promising for research of type 2 diabetes .

HY-N7599

Chrysophanol triglucoside	Phosphatase Glycosidase	Metabolic Disease
Chrysophanol triglucoside is an anthraquinone isolated from Cassia obtusifolia, inhibits protein tyrosine phosphatases 1B (PTP1B) and α-glucosidase with IC₅₀s of 80.17 and 197.06 µM, respectively. Chrysophanol triglucoside has the potential for diabetes research .

HY-N10378

Rubrofusarin 6-O-β-D-glucopyranoside	Phosphatase	Neurological Disease Metabolic Disease
Rubrofusarin 6-O-β-D-glucopyranoside, the glycoside of Rubrofusarin, is a protein tyrosine phosphatase 1B (PTP1B) inhibitor with the IC₅₀ of 87.36 μM. Rubrofusarin 6-O-β-D-glucopyranoside can be used for the research of comorbid diabetes and depression .

HY-159694A

IONIS PTP1BRx sodium ISIS 404173 sodium	Phosphatase	Metabolic Disease
IONIS PTP1BRx (ISIS 404173) sodium is an antisense inhibitor of protein tyrosine phosphatase 1B (PTP-1B). IONIS PTP1BRx sodium shows antidiabetic activity, and can be used for the study of insulin resistance and type 2 diabetes mellitus associated with obesity .

HY-144717

PTP1B-IN-18	Phosphatase	Metabolic Disease
PTP1B-IN-18 is an orally active complete mixed type protein tyrosine phosphatase 1B (PTP1B) inhibitor with a K_i of 35.2 μM. PTP1B-IN-18 can be used for type 2 diabetes research .

HY-163899

(+)-Crinatusin A1	Phosphatase	Metabolic Disease
(+)-Crinatusin A1 (Compound (+)- 4) is a chalcone-monoterpene hybrid, which can be isolated from Cleistocalyx operculatus. (+)-Crinatusin A1 is an inhibitor for **protein tyrosine phosphatase 1B (PTP1B) with IC₅₀** of 0.9 μM. (+)-Crinatusin A1 exhibits potential as an antidiabetic agent .

HY-144718

PTP1B-IN-17	Phosphatase	Metabolic Disease
PTP1B-IN-17 (Compound 45), a potential selective benzimidazole derivative, acts as a protein tyrosine phosphatase 1B (PTP1B) inhibitor with a K_i of 30.2 μM. PTP1B-IN-17 can be used for the research of type 2 diabetes.

HY-144716

PTP1B-IN-19	Phosphatase	Metabolic Disease
PTP1B-IN-19 (Compound 43), a potential selective benzimidazole derivative, acts as a protein tyrosine phosphatase 1B (PTP1B) inhibitor with a K_i of 23.3 μM. PTP1B-IN-19 can be used for the research of type 2 diabetes.

HY-144713

PTP1B-IN-16	Phosphatase	Metabolic Disease
PTP1B-IN-16 (Compound 46), a potential selective benzimidazole derivative, acts as a protein tyrosine phosphatase 1B (PTP1B) inhibitor with a K_i of 12.6 μM. PTP1B-IN-16 can be used for the research of type 2 diabetes.

HY-160514

LXQ46	Phosphatase	Metabolic Disease
LXQ46 is an orally active inhibitor for **protein tyrosine phosphatase 1B (PTP1B), with an IC₅₀** of 0.190 μM. LXQ46 enhances insulin and leptin signaling pathways in insulin-resistant C2C12. LXQ46 ameliorates type 2 diabetes and increases insulin tolerance in mouse models .

HY-N12761

Penpaxilloids A	Phosphatase Glycosidase	Metabolic Disease Inflammation/Immunology
Penpaxilloids A (Compound 1) is a non-competitive inhibitor of protein tyrosine phosphatase 1B (PTP1B) with an IC₅₀ value of 8.60 μM. Penpaxilloids A can be isolated from the fungus Penicillium sp. ZYX-Z-143. Penpaxilloids A is also an α-glucosidase (α-glucosidase) inhibitor with anti-inflammatory activity .

HY-170582

PTP1B-IN-29	Phosphatase	Metabolic Disease
PTP1B-IN-29 (Compound A2B5) is an inhibitor for *phosphatase, that inhibits *protein tyrosine phosphatase 1B (PTP1B), TCPTP and λPPase with IC₅₀**s of 1.27 μM, 4.38 μM and 8.79 μM, respectively. PTP1B-IN-29 can be used in research of diabete and obesity .

HY-162480

PTP1B-IN-27	Glycosidase Phosphatase	Endocrinology
PTP1B-IN-27 (Compound 7i) is an inhibitor of protein tyrosine phosphatase 1-B (PTP‐1B)(IC₅₀=8.2 µM). PTP1B-IN-27 also inhibits α-Glucosidase (IC₅₀=120 µM) and shows competitive inhibition (K_i=118 µM) .

HY-N2451R

Aloe-emodin-8-O-β-D-glucopyranoside (Standard)	Reference Standards Phosphatase	Metabolic Disease Endocrinology
Aloe-emodin-8-O-β-D-glucopyranoside (Standard) is the analytical standard of Aloe-emodin-8-O-β-D-glucopyranoside. This product is intended for research and analytical applications. Aloe-emodin-8-O-β-D-glucopyranoside, a compound isolated from Saussrurea lappa, is a moderate inhibitor of human protein tyrosine phosphatase 1B (hPTP1B) with an IC₅₀ of 26.6 μM .

HY-162499

MY17	Phosphatase	Metabolic Disease
MY17 is an inhibitor of protein tyrosine phosphatase 1B (PTP1B) (IC₅₀=0.41±0.05 μM). MY17 alleviates palmitic acid (PA) -induced insulin resistance by up-regulating the expression of phosphorylated insulin receptor substrate (IRS1) and protein kinase B (AKT). By binding with PTP1B, MY17 can inhibit the activity of PTP1B, thereby improving insulin signaling and having anti-diabetic activity. MY17 can be used in the study of type 2 diabetes .

HY-N1743

1-(4-Hydroxy-2-methoxyphenyl)-3-(4-hydroxy-3-prenylphenyl)	Phosphatase	Metabolic Disease
1-(4-Hydroxy-2-methoxyphenyl)-3-(4-hydroxy-3-prenylphenyl), isolated from Broussonetia kazinoki, shows in vitro inhibition of protein tyrosine phosphatase 1B (PTP1B) with an IC₅₀ of 13.00 μM. PTP1B is a negative regulator of insulin action and an important mediator in the pathogenesis of insulinresistance and non-insulin dependent diabetes mellitus. PTP1B is regarded as a significant target for type 2 diabetes .

HY-162479

PTP1B-IN-26	Phosphatase Amyloid-β	Metabolic Disease
PTP1B-IN-26 (Compound 7a) is a derivative of phenylthiosemicarbazide‐phenoxy‐1,2,3‐triazole‐N‐phenylacetamide. PTP1B-IN-26 is an inhibitor of protein tyrosine *phosphatase 1B* (PTP-1B). PTP1B-IN-26 is a competitive inhibitor. PTP1B-IN-26 can be used to research in type 2 diabetes .

HY-173217

PPARα agonist 5	PPAR Phosphatase	Cardiovascular Disease Metabolic Disease
PPARα agonist 5 is an orally available, selective partial agonist of PPARα (EC₅₀: 3 nM). PPARα agonist 5 reduces lipid accumulation and upregulates key PPARα target genes, exerting anti-fatty liver effects. PPARα agonist 5 also exhibits significant hypolipidemic and hypoglycemic effects through partial PPARγ agonist activity and mild inhibition of protein tyrosine phosphatase 1B (PTP1B) (IC₅₀: 79.1 μM). PPARα agonist 5 has a good safety profile and can be used in the study of type 2 diabetes with dyslipidemia .

HY-149254

PTP1B/AKR1B1-IN-1	Phosphatase Aldose Reductase	Metabolic Disease
PTP1B/AKR1B1-IN-1 is a dual inhibitor of **protein tyrosine phosphatase 1B (PTP1B) and aldose reductase (AKR1B1), with IC₅₀s of 0.06 μM and 4.3 μM, respectively. PTP1B/AKR1B1-IN-1 also inhibits TC-PTP with an IC₅₀** value of 9 μM. PTP1B/AKR1B1-IN-1 serves as an insulin-mimetic agent in murine myoblasts, and reduces AKR1B1-dependent sorbitol accumulation. PTP1B/AKR1B1-IN-1 inhibits development of type 2 diabetes mellitus (T2DM) to control blood glucose levels .

HY-N17455

Albafuran A	Phosphatase	Metabolic Disease Inflammation/Immunology
Albafuran A (Compound 1/4) is a **protein tyrosine phosphatase 1B (PTP1B**) inhibitor and can be used in research related to type 2 diabetes and obesity .

Recombinant Proteins Recommended:

Protein Tyrosine Phosphatase 1B

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P73685

	PTP1B Protein, Human (His) 1 Publications Verification PTP-1B; PTPN1; tyrosine-Protein phosphatase non-receptor type 1	Human	E. coli
	PTP1B is an important tyrosine protein phosphatase that regulates the endoplasmic reticulum unfolded protein response by dephosphorylating EIF2AK3/PERK and inhibiting its kinase activity. It affects the signaling cascade induced by CKII and p60c-src, and may regulate the EFNA5-EPHA3 pathway, affecting cell reorganization. PTP1B Protein, Human (His) is the recombinant human-derived PTP1B protein, expressed by E. coli , with N-His labeled tag.

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Host:	Rabbit (5)
Reactivity:	Human (5)
Application:	IHC-P (4) ICC/IF (3) IP (1) IHC-F (2) WB (5)
Isotype:	IgG (5)
Conjugation:	Non-conjugated (5)
Clonality:	Monoclonal (3) Recombinant (3)
Modification:	Phosphorylated (2) Unmodified (1)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P82031

	PTP1B Antibody (YA1776) PTPN1; PTP1B; tyrosine-Protein phosphatase non-receptor type 1; Protein-tyrosine phosphatase 1B; PTP-1B	WB, IHC-F, IHC-P, ICC/IF	Human
	PTP1B Antibody (YA1776) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PTP1B.

HY-P82031A

	PTP1B Antibody (YA1776)(PBS only) PTPN1; PTP1B; tyrosine-Protein phosphatase non-receptor type 1; Protein-tyrosine phosphatase 1B; PTP-1B	WB, IHC-F, IHC-P, ICC/IF	Human
	PTP1B Antibody (YA1776) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PTP1B.

HY-P81300A

	Phospho-PTP1B (Ser378) Antibody (YA1028) PTPN1; PTP1B; tyrosine-Protein phosphatase non-receptor type 1; Protein-tyrosine phosphatase 1B; PTP-1B	WB, IHC-P	Human
	Phospho-PTP1B (Ser378) Antibody (YA1028) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-PTP1B (Ser378).

HY-P81300AA

	Phospho-PTP1B (Ser378) Antibody (YA1028)(PBS only) PTPN1; PTP1B; tyrosine-Protein phosphatase non-receptor type 1; Protein-tyrosine phosphatase 1B; PTP-1B	WB, IHC-P	Human
	Phospho-PTP1B (Ser378) Antibody (YA1028) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-PTP1B (Ser378).

HY-P81300

	Phospho-PTP1B (Ser352) Antibody (YA1027) PTPN1; PTP1B; tyrosine-Protein phosphatase non-receptor type 1; Protein-tyrosine phosphatase 1B; PTP-1B	WB, ICC/IF, IP	Human
	Phospho-PTP1B (Ser352) Antibody (YA1027) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-PTP1B (Ser352).

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Cat. No.	Product Name		Classification

HY-159694

IONIS PTP1BRx ISIS 404173		Antisense Oligonucleotides
IONIS PTP1BRx (ISIS 404173) is an antisense inhibitor of protein tyrosine phosphatase 1B (PTP-1B). IONIS PTP1BRx shows antidiabetic activity, and can be used for the study of insulin resistance and type 2 diabetes mellitus associated with obesity .

HY-159694A

IONIS PTP1BRx sodium ISIS 404173 sodium		Antisense Oligonucleotides
IONIS PTP1BRx (ISIS 404173) sodium is an antisense inhibitor of protein tyrosine phosphatase 1B (PTP-1B). IONIS PTP1BRx sodium shows antidiabetic activity, and can be used for the study of insulin resistance and type 2 diabetes mellitus associated with obesity .

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Protein tyrosine phosphatase-1B

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