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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
66 Results for "
Protein tyrosine phosphatase-1B
" in MedChemExpress (MCE) Product Catalog:
Products (66)
66 Results for "Protein tyrosine phosphatase-1B" in MCE Product Catalog:
8
8 Publications Verification
Synonyms: Trodusquemine lactate; Aminosterol-1436 lactate
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MSI-1436 lactate is a selective, non-competitive inhibitor of the enzyme protein-tyrosine phosphatase 1B (PTP1B), with an IC50 of 1 μM, 200-fold preference over TCPTP (IC50 of 224 μM).
6
6 Cited Publications
Cat. No.: HY-N0374
CAS No.: 144506-14-9
Category:
Flavonoids Chalcones Leguminosae Metabolic Disease Plants Disease Research Fields Glycyrrhiza uralensis Fisch.
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5
Category:
other families Flavonoids Flavonones Metabolic Disease Phenols Polyphenols Plants Disease Research Fields
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5
5 Cited Publications
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PTP1B-IN-2 is a potent protein tyrosine phosphatase 1B (PTP1B) inhibitor with an IC50 of 50 nM.
2
2 Cited Publications
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TCS 401 is a selective inhibitor of protein tyrosine phosphatase 1B (PTP1B).
2
2 Cited Publications
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KY-226 is a potent, selective, orally active and allosteric protein tyrosine phosphatase 1B (PTP1B) inhibitor with an IC50 of 0.25 μM, and without PPARγ agonist activity. KY-226 exerts anti-diabetic and anti-obesity effects by enhancing insulin and leptin signaling, respectively. KY-226 also protects neurons from cerebral ischemic injury .
1
1 Cited Publications
Cat. No.: HY-N2451
CAS No.: 33037-46-6
Category:
Quinones Liliaceae Monophenols Anthraquinones Metabolic Disease Aloe vera (L.) Burm. f. Phenols Plants Disease Research Fields
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1
1 Cited Publications
Cat. No.: HY-P73685
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PTPN1; Protein-tyrosine phosphatase 1B; Prev. PTP1B; Protein tyrosine phosphatase, Placental; tyrosine-Protein phosphatase Non-Receptor Type 1; PTP-1B; Protein tyrosine phosphatase Non-Receptor Type 1; tyrosine-Protein phosphatase Non-Receptor Type
Species:
Human
Source:
E. coli
Cat. No.: HY-12219
CAS No.: 186139-09-3
Synonyms: Trodusquemine; Aminosterol-1436
Target:
Research Areas:
MSI-1436 is a selective, non-competitive inhibitor of the enzyme protein-tyrosine phosphatase 1B (PTP1B), with an IC50 of appr 1 μM, 200-fold preference over TCPTP (IC50, 224 μM).
Cat. No.: HY-19779
CAS No.: 776309-04-7
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JTT 551 is selective a protein tyrosine phosphatase 1B (PTP1B) inhibitor, with Kis of 0.22 μM and 9.3 μM for PTP1B and TCPTP (T-cell protein tyrosine phosphatase), respectively; JTT 551 can be used in the research of type 2 diabetes mellitus.
Cat. No.: HY-N6650
CAS No.: 20958-15-0
Category:
Quinones Labiatae Samanea saman (Jacq.) Merr. Metabolic Disease Plants Disease Research Fields Naphthalene Quinones
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Lobaric acid is a depsipeptide metabolite isolated from Stereocaulon lichen with antioxidant, antiproliferative, antiviral and enzyme inhibitory activities. Lobaric acid scavenges superoxide free radicals (IC50=97.9 μM) and inhibits cancer cell proliferation (EC50 of 15.2-63.9 μg/mL against leukemia, colorectal, gastric, breast, ovarian, prostate, pancreatic and lung cancer cell lines). Lobaric acid inhibits protein tyrosine phosphatase 1B (PTP1B; IC50=0.87 μM for human recombinant enzyme) and 12(S)-HETE produced by 12(S)-lipoxygenase (IC50=28.5 μM). Lobaric acid (250 μM) also reduced pathological changes in tobacco leaves infected with tobacco mosaic virus (TMV).
Cat. No.: HY-N4143
CAS No.: 27214-72-8
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Cat. No.: HY-N1230
CAS No.: 117204-81-6
Synonyms: Allolicoisoflavone B
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Cat. No.: HY-N3734
CAS No.: 27468-20-8
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Cat. No.: HY-128978
CAS No.: 919091-61-5
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(E,E)-RAMB4 is a potent and selective potent protein tyrosine phosphatase-1B (PTP1B) inhibitor extracted from patent CN103626692A, example 1 .
Cat. No.: HY-N16588
CAS No.: 1085706-32-6
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PTP1B-IN-15 is a potent and selective inhibitor of protein tyrosine phosphatase 1B (PTP1B). PTP1B-IN-15 has the potential for the research of type II diabetes and obesity .
Cat. No.: HY-N8200
CAS No.: 218155-40-9
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
