18 Results for "

Regulator of G protein Signaling

" in MedChemExpress (MCE) Product Catalog:
Products (18)

18 Results for "Regulator of G protein Signaling" in MCE Product Catalog:

32
32 Publications Verification
製品番号: HY-13771
CAS 番号: 128-13-2
純度:  99.94%
別名: Ursodeoxycholate; Ursodiol; UDCA
Ursodeoxycholic acid (Ursodeoxycholate) is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. Ursodeoxycholic acid acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors, including G-protein coupled bile acid receptor 5 (TGR5, GPCR19) and the farnesoid X receptor (FXR). Ursodeoxycholic acid can be used for the research of a variety of hepatic and gastrointestinal diseases. Ursodeoxycholic acid also reduces ACE2 expression and is beneficial for reducing SARS-CoV-2 infection. Orally active .
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32
32 Publications Verification
製品番号: HY-13771A
CAS 番号: 2898-95-5
純度:  99.06%
別名: Ursodeoxycholate sodium; Ursodiol sodium; UCDA sodium
Ursodeoxycholic acid (Ursodeoxycholate) sodium is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. Ursodeoxycholic acid sodium acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors, including G-protein coupled bile acid receptor 5 (TGR5, GPCR19) and the farnesoid X receptor (FXR). Ursodeoxycholic acid sodium can be used for the research of a variety of hepatic and gastrointestinal diseases. Orally active .
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2
2 Cited Publications
製品番号: HY-13509
CAS 番号: 883050-24-6
純度:  99.62%
Target:  

RGS Protein

研究分野:  

Inflammation/Immunology

CCG-50014 is the most potent against the regulator of G-protein signaling protein type 4 (RGS4) (IC50 =30 nM) and is >20-fold selective for RGS4 over other RGS proteins. CCG-50014 binds covalently to the RGS, forming an adduct on two cysteine residues located in an allosteric regulatory site . CCG50014, reduces nociceptive responses and enhances opioid-mediated analgesic effects in the mouse formalin test .
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1
1 Cited Publications
製品番号: HY-113478S
CAS 番号: 347841-46-7
純度:  99.52%
別名: Ursodeoxycholate-d4; Ursodiol-d4; UDCA-d4
Ursodeoxycholic acid-2,2,4,4-d4 is the deuterium labeled Ursodeoxycholic acid (HY-13771). Ursodeoxycholic acid is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. Ursodeoxycholic acid acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors, including G-protein coupled bile acid receptor 5 (TGR5, GPCR19) and the farnesoid X receptor (FXR). Ursodeoxycholic acid can be used for the research of a variety of hepatic and gastrointestinal diseases. Ursodeoxycholic acid also reduces ACE2 expression and is beneficial for reducing SARS-CoV-2 infection .
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製品番号: HY-13771R
CAS 番号: 128-13-2
別名: Ursodeoxycholate (Standard); Ursodiol (Standard); UDCA (Standard)
Ursodeoxycholic acid (Standard) is the analytical standard of Ursodeoxycholic acid. This product is intended for research and analytical applications. Ursodeoxycholic acid (Ursodeoxycholate) is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. Ursodeoxycholic acid acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors, including G-protein coupled bile acid receptor 5 (TGR5, GPCR19) and the farnesoid X receptor (FXR). Ursodeoxycholic acid can be used for the research of a variety of hepatic and gastrointestinal diseases. Ursodeoxycholic acid also reduces ACE2 expression and is beneficial for reducing SARS-CoV-2 infection. Orally active .
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製品番号: HY-175763
CAS 番号: 865271-09-6
Target:  

RGS Protein

Z55660043 is a Regulator of G protein signaling-14 (RGS14) inhibitor with an IC50 of 2.3  μM. Z55660043 selectively and non-covalently inhibits RGS14 GTPase-accelerating protein (GAP) activity without measurable cytotoxicity. Z55660043 can be used for central nervous system and metabolic disorders research .
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製品番号: HY-13771S1
CAS 番号: 63296-46-8
別名: Ursodeoxycholate-13C; Ursodiol-13C; UDCA-13C
Ursodeoxycholic acid- 13C is the 13C labeled Ursodeoxycholic acid. Ursodeoxycholic acid (Ursodeoxycholate) is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. Ursodeoxycholic acid acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors, including G-protein coupled bile acid receptor 5 (TGR5, GPCR19) and the farnesoid X receptor (FXR). Ursodeoxycholic acid can be used for the research of a variety of hepatic and gastrointestinal diseases. Orally active .
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製品番号: HY-13509R
CAS 番号: 883050-24-6
Target:  

RGS Protein

研究分野:  

Inflammation/Immunology

CCG-50014 (Standard) is the analytical standard of CCG-50014. This product is intended for research and analytical applications. CCG-50014 is the most potent against the regulator of G-protein signaling protein type 4 (RGS4) (IC50 =30 nM) and is >20-fold selective for RGS4 over other RGS proteins. CCG-50014 binds covalently to the RGS, forming an adduct on two cysteine residues located in an allosteric regulatory site . CCG50014, reduces nociceptive responses and enhances opioid-mediated analgesic effects in the mouse formalin test .
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製品番号: HY-P701398
純度:  ≥ 90%, as determined by reducing SDS-PAGE.
別名: RGS14; Regulator of G-protein Signaling 14; Regulator of G protein Signaling 14; Regulator of G-protein Signalling 14
Species:  
Human
Source:  
E. coli
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製品番号: HY-P701399
純度:  ≥ 90%, as determined by reducing SDS-PAGE.
別名: RGS14; Regulator of G-protein Signaling 14; Regulator of G protein Signaling 14; Regulator of G-protein Signalling 14
Species:  
Human
Source:  
E. coli
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製品番号: HY-P700384
純度:  ≥ 90%, as determined by reducing SDS-PAGE.
別名: RGS17; RGS-17; Regulator of G protein Signaling 17; Regulator of G-protein Signalling 17; RGSZ2; HRGS17; Regulator of G-protein Signaling 17
Species:  
Human
Source:  
E. coli
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製品番号: HY-P74596
純度:  ≥ 90%, as determined by reducing SDS-PAGE.
別名: RGS5; MSTP106; Regulator of G protein Signaling 5; MSTP129; Regulator of G-protein Signaling 5; MST092; Regulator of G-protein Signalling 5; MST106; MSTP032; MST129; MSTP092
Species:  
Human
Source:  
E. coli
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製品番号: HY-P811720
別名: Regulator of G-protein Signaling 9, RGS9

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP, FC

Reactivity:  

Human, Mouse, Rat

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製品番号: HY-P83466
別名: Regulator of G protein Signaling 6; GAP; S914; HA117

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human

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製品番号: HY-P88488A
別名: Regulator of G-protein Signaling 10, RGS10

Host:  

Mouse

Application:  

IHC-P

Reactivity:  

Human, Mouse, Rat

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製品番号: HY-P811720A
別名: Regulator of G-protein Signaling 9, RGS9

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP, FC

Reactivity:  

Human, Mouse, Rat

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製品番号: HY-P83466A
別名: Regulator of G protein Signaling 6; GAP; S914; HA117

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human

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製品番号: HY-P702984
純度:  ≥ 90%, as determined by reducing SDS-PAGE.
別名: RGS1; Regulator of G-protein Signalling 1; Prev. IER1; Early Response protein 1R20; 1R20; Immediate-Early Response 1, B-Cell Specific; BL34; Epididymis Secretory protein Li 87; Regulator of G-protein Signaling 1; HEL-S-87; IR20; Regulator of G protein Sig
Species:  
Human
Source:  
E. coli
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