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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
22 Results for "
S. mutans
" in MedChemExpress (MCE) Product Catalog:
Products (22)
22 Results for "S. mutans" in MCE Product Catalog:
1
1 Cited Publications
Furanone C-30 is a quorum sensing inhibitor. Furanone C-30 can effectively inhibit bacterial biofilm formation by S. mutans and its luxSmutant strain .
Cat. No.: HY-W004761
CAS No.: 13675-18-8
Synonyms: Hypodiboric acid
Cat. No.: HY-N0078
CAS No.: 20261-38-5
Synonyms: Ginkgolic acid (13:0); Ginkgoneolic Acid; 6-Tridecylsalicylic acid
Cat. No.: HY-P3023
CAS No.: 55466-22-3
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Mutanolysin is a bacteriolytic agent. Mutanolysin is a muralytic enzyme that can prevent hepatic injury. Mutanolysin can digest the cell wall of S. mutans BHT and shows antibacterial activity. Mutanolysin reduces TNF-α production in isolated Kupffer cells stimulated with peptidoglycan-polysaccharide (PG-APS). Mutanolysin can be used for the researches of infection, inflammation and hepatic injury .
Cat. No.: HY-20349
CAS No.: 30233-64-8
Monobehenin, an bacterial biofilm formation inhibitor, has strong inhibitory activity toward bacterial biofilm formation of S. mutans, X. oryzae, and Y. enterocolitica in a strain specific manner .
Cat. No.: HY-P11175
CAS No.: 438620-89-4
Cat. No.: HY-W037825
CAS No.: 2236-60-4
Pterin is a Pteridine with antibacterial activity, which is found in C. croceus. Pterin reduces the proliferation and biofilm production in E. coli, P. aeruginosa, and S. mutans. Pterin is promising for research of cancers and infections .
Cat. No.: HY-P5485
CAS No.: 271798-75-5
Cat. No.: HY-N3341
CAS No.: 179388-53-5
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Macrocarpal H is a natural compound that can be isolated from the Leaves of Eucalyptus globulus. Macrocarpal H exhibits antibacterial activity against Gram-positive cariogenic bacteria and Gram-negative periodontopathic bacteria. Macrocarpal H inhibits adherent water-insoluble glucan synthesis via glucosyltransferase. Macrocarpal H can be used for the research of caries, periodontal disease, dental caries, periodontal disorders .
Research Areas:
G43 is a potent, selective glucosyltransferase inhibitor, with the Kd of 3.7μM and 46.9 nM for GtfB and GtfC, respectively. G43 has antibacterial to S. mutans in vitro and in vivo, and can be used for dental caries study .
Cat. No.: HY-P5573
CAS No.: 302343-10-8
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Cat. No.: HY-P5574
CAS No.: 302343-11-9
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Cat. No.: HY-401757
CAS No.: 198649-97-7
Anticaries agent-1 (Compound 21b) is an anticaries agent. Anticaries agent-1 inhibits biofilm formation (IC50: 77 μM) and S. mutans growth .
Cat. No.: HY-147958
Antibacterial agent 113 (compound 3) is a potent antibacterial agent. Antibacterial agent 113 shows antibacterial activity against P.aeruginosa, S.mutans, B.subtilis, E.coli, E.faecalis, S.typhimuriumand, and S.aureus microorganisms, with MIC values all of 156.25 μM .
Cat. No.: HY-147957
Antibacterial agent 112 (compound 2) is a potent antibacterial agent. Antibacterial agent 112 shows antibacterial activity against P.aeruginosa, S.mutans, B.subtilis, E.coli, E.faecalis, S.typhimuriumand, and S.aureus microorganisms, with MIC values of 625, 625, 1250, 1250, 1250, 1250 and 1250 μM, respectively .
Cat. No.: HY-147959
CAS No.: 2733391-71-2
Antibacterial agent 114 (compound 1) is a potent antibacterial agent. Antibacterial agent 114 shows antibacterial activity against P.aeruginosa, B.subtilis, E.coli, E.faecalis, S.typhimuriumand, S.mutans, and S.aureus microorganisms, with MIC values of 625, 625, 625, 625, 625, 1250 and 1250 μM, respectively .
Cat. No.: HY-N7854
CAS No.: 103904-74-1
Synonyms: Anacardic acid 15:2
Anacardic acid diene is a polyunsaturated form of anacardic acid (HY-N2020) that has been found in cashew nut shell liquid. It has antibacterial activity against methicillin resistant S. aureus (MRSA) and S. mutans (MICs=12.5 and 6.25 μg/mL, respectively). Anacardic acid diene has schistosomicidal activity against adult S. mansoni worms when used at a concentration of 100 μM. It also inhibits soybean lipoxygenase-1 in a time-dependent manner.
Cat. No.: HY-169308
CAS No.: 2809982-20-3
EGFR-IN-132 (Compound 23) is an inhibitor for EGFR, that inhibits the EGFR wildtype, L858R/T790M, d19/T790M, L858R/T790M/C797S, and d19/T790M/C797S mutans with IC50 of 1.6, 0.025, 0.019, 0.022, and 0.029 nM. EGFR-IN-132 exhibits good pharmacokinetics characteristics with high oral exposure .
Cat. No.: HY-169309
CAS No.: 2809982-26-9
EGFR-IN-133 (Compound 24) is an inhibitor for EGFR, that inhibits the EGFR wildtype, L858R/T790M, d19/T790M, L858R/T790M/C797S, and d19/T790M/C797S mutans with IC50 of 0.1, 0.044, 0.036, 0.04, and 0.054 nM. EGFR-IN-133 exhibits good pharmacokinetics characteristics with high oral exposure .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
