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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
SASP
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "SASP" in MCE Product Catalog:
10
Category:
Rosaceae Crataegus pinnatifida Bge. Plants Flavonoids Functional Molecules Research of Health Products Phenols Polyphenols Disease Research Fields Biflavones Cancer
Target:
3
Target:
Research Areas:
1
1
1 Cited Publications
Cat. No.: HY-P73431A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Thioredoxin; TXN; Trx; ADF; TRX1; SASP
Category:
Infection Simple Phenylpropanols Solanum torvum Swartz Phenols Polyphenols Phenylpropanoids Plants Solanaceae Disease Research Fields
Target:
Cat. No.: HY-N2342R
CAS No.: 37064-30-5
Synonyms: PCC1 (Standard)
Target:
Cat. No.: HY-RS01106
Target:
Research Areas:
ASPRV1 Human Pre-designed siRNA Set A contains three designed siRNAs for ASPRV1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P73432A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Thioredoxin; TXN; Trx; ADF; TRX1; SASP
Cat. No.: HY-P85388
Synonyms: TXN; TRDX; TRX; TRX1; Thioredoxin; Trx; ATL-derived factor; ADF; Surface-associated sulphydryl protein; SASP
Cat. No.: HY-P85388A
Synonyms: TXN; TRDX; TRX; TRX1; Thioredoxin; Trx; ATL-derived factor; ADF; Surface-associated sulphydryl protein; SASP
Cat. No.: HY-181604
CAS No.: 3047410-41-0
Target:
Research Areas:
MDH2-IN-2 is an orally active MDH2 inhibitor with an IC50 of 5.9 μM. MDH2-IN-2 reduces the levels of senescence markers and senescence-associated secretory phenotype (SASP) factors in mammalian cell models. MDH2-IN-2 extends the lifespan and improves the healthspan of Caenorhabditis elegans. MDH2-IN-2 alleviates tissue senescence in aged mice, inhibits SASP factors, and restores liver and kidney functions. MDH2-IN-2 is applicable for senescence-related research .
Cat. No.: HY-184158
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Research Areas:
HATC is a HIF-1α AUTAC degrader. HATC links HIF-1α to LC3 to form a ternary complex that undergoes degradation via the autophagy-lysosome fusion pathway. HATC induces dose-dependent HIF-1α degradation in multiple cell types. HATC reduces visceral fat accumulation, hepatic lipid deposition, senescent cell aggregation, and bone loss; alleviates age-related intervertebral disc degeneration, liver dysfunction, kyphosis, and alveolar dilation; decreases circulating lactic acid levels; improves physical performance; and reverses age-related changes in granulocyte proportions. HATC extends median and maximum lifespan, reduces transcriptomic age, and causes no obvious persistent toxicity. HATC can be used in the research of age-related diseases (pink: LC3 ligand (HY-50759); blue: HIF-1α ligand (HY-P10426); Linker: (HY-W008264)) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
