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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
16 Results for "
SCN2
" in MedChemExpress (MCE) Product Catalog:
Products (16)
16 Results for "SCN2" in MCE Product Catalog:
Cat. No.: HY-178106
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SCN2 is a esterase-responsive prodrug-based amphiphile composed of SN38 (HY-13704) and di-(triazole-[12]aneN3, N) moiety through a 7‑carbon alkyl chains. SCN2 has excellent self-assembly and reversible siRNA condensation capabilities as well as anti-proliferation activity against cancer cells. SCN2 can be used for synthesis of nanoparticles for drug delivery of lung cancer .
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ARN1468 (compound 5) is an orally active and potent SerpinA3n inhibitor. ARN1468 can inhibit serpins activity would set the protease free to further reduce prion accumulation. ARN1468 shows anti-prion effect in ScGT1 RML, ScGT1 22L, ScN2a RML, and ScN2a 22L cell lines, with EC50 values of 8.64, 19.3, 11.2, and 6.27 μM .
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DNA, d([2′-O-(2-methoxyethyl)](m5rC-sp-m5rC-rA-m5rC-rG-rA)-m5C-sp-A-sp-T-sp-A-sp-T-sp-T-sp-T-sp-T-sp-T-sp-m5C-sp-[2′-O-(2-methoxyethyl)]m5rU-[2′-O-(2-methoxyethyl)]rA-sp-[2′-O-(2-methoxyethyl)]m5rC-sp-[2′-O-(2-methoxyethyl)]rA)
Cat. No.: HY-177629
CAS No.: 2756001-75-7
Synonyms: PRAX-222
Cat. No.: HY-RS05378
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GFI1 Human Pre-designed siRNA Set A contains three designed siRNAs for GFI1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-W081348
CAS No.: 60798-06-3
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1-(4-Methoxyphenyl)-3-methyl-1H-pyrazol-5(4H)-one (Compound 2) has antiprion activity in ScN2a and F3 cells with IC50 values of 13 nM and 25 nM, respectively .
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DNA, d([2′-O-(2-methoxyethyl)](m5rC-sp-m5rC-rA-m5rC-rG-rA)-m5C-sp-A-sp-T-sp-A-sp-T-sp-T-sp-T-sp-T-sp-T-sp-m5C-sp-[2′-O-(2-methoxyethyl)]m5rU-[2′-O-(2-methoxyethyl)]rA-sp-[2′-O-(2-methoxyethyl)]m5rC-sp-[2′-O-(2-methoxyethyl)]rA), sodium salt
Cat. No.: HY-177629A
Synonyms: PRAX-222 sodium
Cat. No.: HY-RS12529
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SCN2A Human Pre-designed siRNA Set A contains three designed siRNAs for SCN2A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS12530
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Scn2a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Scn2a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS12531
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Scn2a Rat Pre-designed siRNA Set A contains three designed siRNAs for Scn2a gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS12532
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SCN2B Human Pre-designed siRNA Set A contains three designed siRNAs for SCN2B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
TCS PrP Inhibitor 13, an antiprion agent, is a cellular prion protein (PrP C) inhibitor. TCS PrP Inhibitor 13, as a protease-resistant form of prion protein (PrP-res) accumulation inhibitor, shows an IC50 value of 3 nM in both ScN2a and F3 cell lines. TCS PrP Inhibitor 13 induces Schwannoma cells apoptosis .
Cat. No.: HY-RS20102
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Scn2b Mouse Pre-designed siRNA Set A contains three designed siRNAs for Scn2b gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS26605
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Scn2b Rat Pre-designed siRNA Set A contains three designed siRNAs for Scn2b gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-107662R
CAS No.: 34320-83-7
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TCS PrP Inhibitor 13 (Standard) is the analytical standard of TCS PrP Inhibitor 13 (HY-107662). This product is intended for research and analytical applications. TCS PrP Inhibitor 13, an antiprion agent, is a cellular prion protein (PrPC) inhibitor. TCS PrP Inhibitor 13, as a protease-resistant form of prion protein (PrP-res) accumulation inhibitor, shows an IC50 value of 3 nM in both ScN2a and F3 cell lines. TCS PrP Inhibitor 13 induces Schwannoma cells apoptosis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
