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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
46 Results for "
Simvastatin
" in MedChemExpress (MCE) Product Catalog:
Products (46)
46 Results for "Simvastatin" in MCE Product Catalog:
89
Research Areas:
Simvastatin (MK 733) is a competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM.
12
12 Cited Publications
Synonyms: MVA lithium salt
Target:
5
5 Cited Publications
Synonyms: 20α-Hydroxycholesterol
Target:
1
Research Areas:
Simvastatin acid (Tenivastatin), a hydrolysate of Simvastatin (HY-17502), is a HMG-CoA reductase (HMGCR) inhibitor. Simvastatin acid reduces Indoxyl sulfate-mediated reactive oxygen species (ROS) production in human cardiomyocytes. Simvastatin acid can also modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene .
1
1 Cited Publications
Synonyms: Tenivastatin sodium; Simvastatin Impurity A sodium
Research Areas:
Simvastatin hydroxy acid (Tenivastatin) sodium is a potent HMG-CoA reductase (HMGCR) inhibitor. Simvastatin hydroxy acid sodium reduces Indoxyl sulfate-mediated reactive oxygen species (ROS) production in human cardiomyocytes. Simvastatin hydroxy acid sodium can also modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene .
1
1 Cited Publications
Synonyms: Tenivastatin ammonium
Category:
Human Gut Microbiota Metabolites Immune System Disorder Ketones, Aldehydes, Acids Other Diseases Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields
Target:
Cat. No.: HY-W341625
CAS No.: 474943-80-1
Target:
Research Areas:
Trihexosylceramide (d18:1/12:0) is a glycosphingolipid and mood-related compound. Trihexosylceramide (d18:1/12:0) is characterized by elevated serum levels in Mus musculus fed a high-fat diet, and its levels are positively correlated with mood Z-scores. Accumulation of Trihexosylceramide (d18:1/12:0) in tissues is considered the etiology of angiokeratoma corporis diffusum. Trihexosylceramide (d18:1/12:0) can be used in studies related to high-fat diet-induced mood disorders .\n
Cat. No.: HY-17502R
CAS No.: 79902-63-9
Synonyms: MK 733 (Standard)
Research Areas:
Simvastatin (Standard) is the analytical standard of Simvastatin. This product is intended for research and analytical applications. Simvastatin (MK 733) is a competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM.
Synonyms: MK 733-d6
Cat. No.: HY-17502S1
CAS No.: 1002347-61-6
Synonyms: MK 733-d3
Cat. No.: HY-W654341
Cat. No.: HY-119695B
CAS No.: 530112-57-3
Synonyms: Tenivastatin calcium hydrate
Research Areas:
Simvastatin acid (Tenivastatin) calcium hydrate is a potent HMG-CoA reductase (HMGCR) inhibitor. Simvastatin acid calcium hydrate reduces Indoxyl sulfate-mediated reactive oxygen species (ROS) production in human cardiomyocytes. Simvastatin acid calcium hydrate can also modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene .
Cat. No.: HY-135402
CAS No.: 79902-42-4
Target:
Research Areas:
2'-Ethyl Simvastatin (compound 6) is a Mevinolin analog, with HMG-CoA reductase inhibition .
Cat. No.: HY-119695AS2
Synonyms: Tenivastatin-d3 ammonium
Cat. No.: HY-135404
CAS No.: 210980-68-0
Synonyms: Dehydro Simvastatin
Target:
Research Areas:
Anhydrosimvastatin (Impurity C) is an impurity of Simvastatin. Simvastatin is a competitive inhibitor of HMG-CoA reductase .
Cat. No.: HY-136345A
CAS No.: 1283861-33-5
Target:
Research Areas:
3'-Hydroxy simvastatin is a metabolite of simvastatin. Simvastatin (HY-17502) is an orally active competitive inhibitor of HMG-CoA reductase (HMGCR) (Ki: 0.2 nM) .
Cat. No.: HY-135404R
CAS No.: 210980-68-0
Synonyms: Dehydro Simvastatin (Standard)
Target:
Research Areas:
Anhydrosimvastatin (Standard) is the analytical standard of Anhydrosimvastatin. This product is intended for research and analytical applications. Anhydrosimvastatin (Impurity C) is an impurity of Simvastatin. Simvastatin is a competitive inhibitor of HMG-CoA reductase .
Cat. No.: HY-113071C
CAS No.: 32451-23-3
Synonyms: (S)-MVA
Target:
Research Areas:
Cardiovascular Disease Neurological Disease Metabolic Disease
(S)-Mevalonic acid is the isomer of Mevalonic acid (HY-113071). Mevalonic acid ((S)-DCIT) is a precursor substance of the mevalonate pathway, which is essential for cell growth and proliferation. Mevalonic acid is effective in inhibiting Simvastatin (HY-17502)-induced decrease in C2C12 cell viability in vitro. Mevalonic acid can be used in studies of myopathy and heart failure .
Cat. No.: HY-135405
CAS No.: 145576-25-6
Target:
Research Areas:
4-Acetylsimvastatin is an acetylated simvastatin. Simvastatin is a competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
