19 Results for "

TGN

" in MedChemExpress (MCE) Product Catalog:
Products (19)

19 Results for "TGN" in MCE Product Catalog:

25
25 Cited Publications
Cat. No.: HY-W008574
CAS No.: 51987-99-6
Target:  

PROTAC Linkers

Research Areas:  

Inflammation/Immunology Cancer

TGN-020 is a selective Aquaporin 4 (AQP4) inhibitor with an IC50 of 3.1 μM . TGN-020 is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs [3].TGN-020 alleviates edema and inhibits glial scar formation after spinal cord compression injury in rats .
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25
25 Cited Publications
Cat. No.: HY-W008574A
CAS No.: 1313731-99-5
Target:  

PROTAC Linkers

Research Areas:  

Inflammation/Immunology Cancer

TGN-020 sodium is a selective Aquaporin 4 (AQP4) inhibitor with an IC50 of 3.1 μM . TGN-020 sodium is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . TGN-020 sodium alleviates edema and inhibits glial scar formation after spinal cord compression injury in rats .
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Cat. No.: HY-P9975
CAS No.: 906068-56-2
Synonyms: TGN1412; TAB08

Target:  

CD28

Research Areas:  

Inflammation/Immunology

Theralizumab (TGN1412) is a humanized lgG4 superagonistic anti-CD28 monoclonal antibody that directly stimulates T cells. Theralizumab can cause cytokine release syndrome (CRS). Theralizumab can be used for the research of rheumatoid arthritis .
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Cat. No.: HY-W176557
CAS No.: 877459-36-4
Target:  

Aquaporin Amyloid-β

Research Areas:  

Neurological Disease

TGN-073 is an orally active, blood-brain barrier-permeable aquaporin 4 (AQP4) modulator. TGN-073 increases the uptake and distribution of brain MRI tracers in the brain parenchyma and reduces the levels of insoluble amyloid β-40 and β-42. TGN-073 can be used in research related to Alzheimer's disease, dementia, traumatic brain injury and pain .
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Cat. No.: HY-137975
CAS No.: 304684-77-3
Purity:  99.96%
Target:  

Bacterial

Research Areas:  

Endocrinology

Exo2 is a secretion inhibitor. Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network. Exo2 blocks secretory cargo exit from the ER (endoplasmic reticulum) and disrupts the Golgi apparatus, but does not affect the morphology of the TGN (trans-Golgi network) Exo2 can stimulate calcium-dependent exocytosis in permeabilized adrenal chromaff in cells .
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Cat. No.: HY-P11284
CAS No.: 1312882-14-6
Target:  

Peptides

Research Areas:  

Neurological Disease

TGN, a 12-amino acid ligand, is a BBB-penetrating peptide. TGN can be used as a drug delivery vehicle for Alzheimer's disease research .
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Cat. No.: HY-P10942
CAS No.: 2421211-40-5
Research Areas:  

Neurological Disease

CGN peptide is a 13 amino acid peptide composed of D-amino acids, referred to as CGN peptide. CGN peptide is the retro-inverso isomer of the l-peptide TGN (TGNYKALHPHNG) and can deliver siRNA to the blood-brain barrier (BBB). CGN peptide can be used in Alzheimer's disease (AD) research .
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Cat. No.: HY-P10942A
Research Areas:  

Neurological Disease

CGN peptide TFA is a 13 amino acid peptide composed of D-amino acids, referred to as CGN peptide. CGN peptide TFA is the retro-inverso isomer of the l-peptide TGN (TGNYKALHPHNG) and can deliver siRNA to the blood-brain barrier (BBB). CGN peptide TFA can be used in Alzheimer's disease (AD) research .
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Cat. No.: HY-10270
CAS No.: 871576-03-3
Synonyms: TGN 255
Target:  

Thrombin

Research Areas:  

Cardiovascular Disease

Flovagatran (TGN 255) is a potent and reversible thrombin inhibitor (Ki: 9 nM). Flovagatran can be used in the research of arterial and venous thrombosis .
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Cat. No.: HY-10271
CAS No.: 871575-98-3
Synonyms: TGN 255 sodium
Target:  

Thrombin

Research Areas:  

Cardiovascular Disease

Flovagatran (TGN 255) sodium is a potent and reversible thrombin inhibitor (Ki: 9 nM). Flovagatran sodium can be used in the research of arterial and venous thrombosis .
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Cat. No.: HY-RS22983
Research Areas:  

Others

Tg Rat Pre-designed siRNA Set A contains three designed siRNAs for Tg gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS14432
Research Areas:  

Others

TG Human Pre-designed siRNA Set A contains three designed siRNAs for TG gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS16550
Research Areas:  

Others

Tg Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tg gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P11284B
CAS No.: 1418155-47-1
Target:  

Drug Derivative

Research Areas:  

Neurological Disease

TGN, Cys modified is a cysteine modified TGN (HY-P11284) on the C-terminus. TGN, a 12-amino acid ligand, is a BBB-penetrating peptide. TGN can be used as a drug delivery vehicle for Alzheimer's disease research .
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Cat. No.: HY-P11284C
Target:  

Peptides

Research Areas:  

Neurological Disease

TGN acetate, a 12-amino acid ligand, is a BBB-penetrating peptide. TGN acetate can be used as a drug delivery vehicle for Alzheimer's disease research .
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Cat. No.: HY-P83483
Synonyms: TGN38; TGN46; TGN48; TGN51; TGOLN2; TTGN2

Host:  

Rabbit

Application:  

WB, IHC-P, IP

Reactivity:  

Human

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Cat. No.: HY-P83483A
Synonyms: TGN38; TGN46; TGN48; TGN51; TGOLN2; TTGN2

Host:  

Rabbit

Application:  

WB, IHC-P, IP

Reactivity:  

Human

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Cat. No.: HY-P71030
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Trans-Golgi network integral membrane protein 2; TGN38 homolog; TGN46; TGN48; Trans-Golgi network protein TGN51; TGOLN2; TGN46; TGN51
Species:  
Source:  
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Cat. No.: HY-P810363
Synonyms: AITD 3, AITD3, hTG, TDH3, Tg, TGN, THYG_HUMAN, Thyroglobulin

Host:  

Rabbit

Application:  

WB, IHC-P, IF-Tissue

Reactivity:  

Human

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