42 Results for "

THC

" in MedChemExpress (MCE) Product Catalog:
Products (42)

42 Results for "THC" in MCE Product Catalog:

7
7 Publications Verification
Cat. No.: HY-B0151
CAS No.: 145-13-1
Synonyms: 3β-Hydroxy-5-pregnen-20-one
Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication . Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels .
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7
7 Publications Verification
Cat. No.: HY-B1739
CAS No.: 1247-64-9
Synonyms: 3β-Hydroxy-5-pregnen-20-one monosulfate
Pregnenolone monosulfate (3β-Hydroxy-5-pregnen-20-one monosulfate) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone monosulfate acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone monosulfate can protect the brain from cannabis intoxication . Pregnenolone monosulfate is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels .
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7
7 Publications Verification
Cat. No.: HY-110189
CAS No.: 1852-38-6
Purity:  99.96%
Synonyms: 3β-Hydroxy-5-pregnen-20-one monosulfate sodium
Pregnenolone monosulfate sodium (3β-Hydroxy-5-pregnen-20-one monosulfate sodium) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone monosulfate sodium acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone monosulfate sodium can protect the brain from cannabis intoxication . Pregnenolone monosulfate sodium is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels .
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6
6 Cited Publications
Cat. No.: HY-B0151R
CAS No.: 145-13-1
Synonyms: 3β-Hydroxy-5-pregnen-20-one (Standard)
Pregnenolone (Standard) is the analytical standard of Pregnenolone. This product is intended for research and analytical applications. Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication . Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels .
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Cat. No.: HY-168828
CAS No.: 134840-81-6
Target:  

Drug Derivative

Research Areas:  

Neurological Disease

Δ9-THC-ethyl is an ethyl-chain homolog of Tetrahydrocannabinol.
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Cat. No.: HY-W775262
CAS No.: 23978-85-0
Target:  

Cannabinoid Receptor

Research Areas:  

Neurological Disease

Δ9-Tetrahydrocannabinolic acid (Δ9-THCA) is a phytocannabinoid that can be heated by cigarette carriers to produce Δ9-THC, thus having psychoactive properties .
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Cat. No.: HY-159161
CAS No.: 2237222-16-9
Target:  

Orphan GPCR

Research Areas:  

Inflammation/Immunology Cancer

PSB-CB-27 is a potent and selective GPR18 inhibitor with an IC50 of 0.65 μM. PSB-CB-27 shows selectivity over Human GPR55, Human CB1 receptor, and Human CB2 receptor. PSB-CB-27 leads to a complete blockade of Δ9-Tetrahydrocannabinol (THC)-induced GPR18 activation. PSB-CB-27 can be used for inflammatory diseases and cancer immunotherapy research .
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Cat. No.: HY-B0151S2
CAS No.: 61574-54-7
Synonyms: 3β-Hydroxy-5-pregnen-20-one-d4-1
Pregnenolone-d4-1 is the deuterium labeled Pregnenolone. Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication . Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels .
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Cat. No.: HY-W127407
CAS No.: 201738-25-2
Glycerophospho-N-Arachidonoyl Ethanolamine is a N-acylated ethanolamines (NAEs). Most NAEs are naturally occurring lipids with diverse biological activities. Different types of NAE can be derived from glycerophosphate-linked precursors through the activity of glycerophosphodiesterase 1 (GDE1). Glycerophosphate-N-Arachidonoyl Ethanolamine is the precursor of Anandamide (AEA), also known as Anandamide. AEA is an endocannabinoid neurotransmitter that binds to central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. It inhibits the specific binding of [3H]-HU-243 to synaptosomal membranes with a Ki value of 52 nM compared to 46 nM for δ9-THC.
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Cat. No.: HY-110189S1
CAS No.: 1485492-21-4
Synonyms: 3β-Hydroxy-5-pregnen-20-one monosulfate-d4 sodium
Pregnenolone monosulfate-d4 sodium is the deuterium labeled Pregnenolone monosulfate sodium (HY-110189) . Pregnenolone monosulfate sodium (3β-Hydroxy-5-pregnen-20-one monosulfate sodium) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone monosulfate sodium acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone monosulfate sodium can protect the brain from cannabis intoxication . Pregnenolone monosulfate sodium is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels .
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Cat. No.: HY-170477
CAS No.: 51768-60-6
Synonyms: Δ8-Tetrahydrocannabiphorol; n-Heptyl ∆8-THC
Target:  

Cannabinoid Receptor

Research Areas:  

Others

Δ8-THCP (Δ8-Tetrahydrocannabiphorol; n-Heptyl Δ8-THC) (Compound 1a) is a semisynthetic cannabinoid that serves as an analytical reference standard and exhibits affinity for the CB1 receptor .
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Cat. No.: HY-169039
CAS No.: 860480-30-4
Synonyms: Δ9-Tetrahydrocannabinoquinone
Target:  

Drug Metabolite

Research Areas:  

Others

Δ9-THCQ (Δ9-Tetrahydrocannabinoquinone) is an oxidative byproduct of Δ9-THC .
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Cat. No.: HY-123410
CAS No.: 628263-22-9
Target:  

Cannabinoid Receptor

Research Areas:  

Cancer

KM-233 is a classical cannabinoid with good blood brain barrier penetration. KM-233 possesses a selective affinity for the CB2 receptors relative to THC. KM-233 is effective at reducing U87 glioma tumor burden, and can be used for glioma research .
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Cat. No.: HY-B0151S
Synonyms: 3β-Hydroxy-5-pregnen-20-one-d4
Pregnenolone-d4 is the deuterium labeled Pregnenolone. Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication . Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels .
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Cat. No.: HY-B0151S1
CAS No.: 2483824-26-4
Synonyms: 3β-Hydroxy-5-pregnen-20-one-13C2,d2
Pregnenolone- 13C2,d2 is the deuterium and 13C labeled Pregnenolone (HY-B0151). Pregnenolone is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication. Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels .
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Cat. No.: HY-W775346
CAS No.: 23050-54-6
Synonyms: Δ8-THC acetate; Delta8-tetrahydrocannabinol
Delta8-THC acetate (Delta8-tetrahydrocannabinol) is a psychoactive phytocannabinoid, that binds to cannabinoid receptor 1 (CB1 receptor), and exhibits anti-nausea, appetite-stimulating, and anti-inflammatory activities. Delta8-THC acetate exhibits probably neuroprotective efficacy and can be used in anti-anxiety and antidepressant research .
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Cat. No.: HY-150345
CAS No.: 62667-60-1
Target:  

Cannabinoid Receptor

Research Areas:  

Neurological Disease

Δ8-THC Glucuronide is a phytocannabinoid metabolite .
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Cat. No.: HY-103451A
CAS No.: 138090-06-9
Target:  

Estrogen Receptor/ERR

Research Areas:  

Metabolic Disease

rel-(R,R)-THC is the relative configuration of (R,R)-THC (HY-103451). (R,R)-THC is an ERα agonist and an ERβ antagonist, with Kis of 9.0 nM and 3.6 nM for ERα and ERβ, respectively. (R,R)-THC has higher relative binding affinity for ERβ than ERα with the values of 25 and 3.6 .
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Cat. No.: HY-168355
CAS No.: 1451-20-3
Target:  

Cannabinoid Receptor

Research Areas:  

Neurological Disease

Δ8-THC methyl ether (compound 3) shows a good docking score (-10.167 kcal/mol) for CB2 receptor. Δ8-THC methyl ether has antinociceptive activity in mice .
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Cat. No.: HY-103451
CAS No.: 221368-54-3
Purity:  ≥99.0%
Target:  

Estrogen Receptor/ERR

Research Areas:  

Metabolic Disease

(R,R)-THC is an ERα agonist and an ERβ antagonist, with Kis of 9.0 nM and 3.6 nM for ERα and ERβ, respectively. (R,R)-THC has higher relative binding affinity for ERβ than ERα with the values of 25 and 3.6 .
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