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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
29 Results for "
TL1A
" in MedChemExpress (MCE) Product Catalog:
Products (29)
29 Results for "TL1A" in MCE Product Catalog:
1
Target:
Research Areas:
1
1 Cited Publications
Cat. No.: HY-P990876
CAS No.: 2911580-96-4
Synonyms: PF-06480605 (WT IgG1); RVT-3101 (WT IgG1)
Target:
Research Areas:
Afimkibart (PF-06480605; RVT-3101) is a fully human monoclonal antibody that selectively inhibits trimeric tumor necrosis factor-like ligand 1A (TL1A). Afimkibart neutralizes active trimeric TL1A, blocks TL1A-induced signaling pathways. Afimkibart inhibits NF-κB activation and IFN-γ production. Afimkibart can be used for the research of inflammatory bowel disease [1].
1
1 Cited Publications
Cat. No.: HY-P990006
CAS No.: 2750005-84-4
Synonyms: TEV-48574; SAR-447189; TEV-574
Target:
Research Areas:
Cat. No.: HY-P990151
Target:
Research Areas:
Cat. No.: HY-P991440
Target:
Research Areas:
Cat. No.: HY-P71913
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF15; TL1A; TNF Superfamily Member 15; Vascular Endothelial Growth Inhibitor-192A; Vascular Endothelial Cell Growth Inhibitor; Vascular Endothelial Growth Inhibitor; TNF Ligand-Related Molecule 1; TNF Superfamily Ligand TL1A; VEGI; MGC129934; TL1; MGC1
Species:
Human
Source:
E. coli
Cat. No.: HY-P700153AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF15; TL1A; TNF Superfamily Member 15; Vascular Endothelial Growth Inhibitor-192A; Vascular Endothelial Cell Growth Inhibitor; Vascular Endothelial Growth Inhibitor; TNF Ligand-Related Molecule 1; TNF Superfamily Ligand TL1A; VEGI; MGC129934; TL1; MGC1
Species:
Human
Source:
E. coli
Cat. No.: HY-P77939
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: TNFSF15; TL1A; TNF Superfamily Member 15; Vascular Endothelial Growth Inhibitor-192A; Vascular Endothelial Cell Growth Inhibitor; Vascular Endothelial Growth Inhibitor; TNF Ligand-Related Molecule 1; TNF Superfamily Ligand TL1A; VEGI; MGC129934; TL1; MGC1
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P78447
Purity: ≥ 95%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: TNFSF15; TL1A; TNF Superfamily Member 15; Vascular Endothelial Growth Inhibitor-192A; Vascular Endothelial Cell Growth Inhibitor; Vascular Endothelial Growth Inhibitor; TNF Ligand-Related Molecule 1; TNF Superfamily Ligand TL1A; VEGI; MGC129934; TL1; MGC1
Species:
Human
Source:
HEK293
Cat. No.: HY-P700839
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF15; TL1A; TNF Superfamily Member 15; Vascular Endothelial Growth Inhibitor-192A; Vascular Endothelial Cell Growth Inhibitor; Vascular Endothelial Growth Inhibitor; TNF Ligand-Related Molecule 1; TNF Superfamily Ligand TL1A; VEGI; MGC129934; TL1; MGC1
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P701046
Purity: ≥ 90%, as determined by Bis-Tris PAGE.
Synonyms: TNFSF15; TL1A; TNF Superfamily Member 15; Vascular Endothelial Growth Inhibitor-192A; Vascular Endothelial Cell Growth Inhibitor; Vascular Endothelial Growth Inhibitor; TNF Ligand-Related Molecule 1; TNF Superfamily Ligand TL1A; VEGI; MGC129934; TL1; MGC1
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P701048
Purity: ≥ 95%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: TNFSF15; TL1A; TNF Superfamily Member 15; Vascular Endothelial Growth Inhibitor-192A; Vascular Endothelial Cell Growth Inhibitor; Vascular Endothelial Growth Inhibitor; TNF Ligand-Related Molecule 1; TNF Superfamily Ligand TL1A; VEGI; MGC129934; TL1; MGC1
Species:
Human
Source:
HEK293
Cat. No.: HY-P704925
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF15; TL1A; TNF Superfamily Member 15; Vascular Endothelial Growth Inhibitor-192A; Vascular Endothelial Cell Growth Inhibitor; Vascular Endothelial Growth Inhibitor; TNF Ligand-Related Molecule 1; TNF Superfamily Ligand TL1A; VEGI; MGC129934; TL1; MGC1
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P71981
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF15; TL1A; TNF Superfamily Member 15; Vascular Endothelial Growth Inhibitor-192A; Vascular Endothelial Cell Growth Inhibitor; Vascular Endothelial Growth Inhibitor; TNF Ligand-Related Molecule 1; TNF Superfamily Ligand TL1A; VEGI; MGC129934; TL1; MGC1
Species:
Human
Source:
HEK293
Cat. No.: HY-P701047
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF15; TL1A; TNF Superfamily Member 15; Vascular Endothelial Growth Inhibitor-192A; Vascular Endothelial Cell Growth Inhibitor; Vascular Endothelial Growth Inhibitor; TNF Ligand-Related Molecule 1; TNF Superfamily Ligand TL1A; VEGI; MGC129934; TL1; MGC1
Species:
Rhesus Macaque
Cynomolgus
Source:
HEK293
Cat. No.: HY-P72446
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF15; TL1A; TNF Superfamily Member 15; Vascular Endothelial Growth Inhibitor-192A; Vascular Endothelial Cell Growth Inhibitor; Vascular Endothelial Growth Inhibitor; TNF Ligand-Related Molecule 1; TNF Superfamily Ligand TL1A; VEGI; MGC129934; TL1; MGC1
Species:
Mouse
Source:
E. coli
Cat. No.: HY-P702569
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF15; TL1A; TNF Superfamily Member 15; Vascular Endothelial Growth Inhibitor-192A; Vascular Endothelial Cell Growth Inhibitor; Vascular Endothelial Growth Inhibitor; TNF Ligand-Related Molecule 1; TNF Superfamily Ligand TL1A; VEGI; MGC129934; TL1; MGC129935; Tumor Necrosis Factor (Ligand) Superfamily, Member 15; Tumor Necrosis Factor Superfamily Member 15; Tumor Necrosis Factor Ligand Superfamily Member 15; Tumor Necrosis Factor Ligand 1B; VEGI192A; TNLG1B
Species:
Human
Source:
HEK293
Cat. No.: HY-P702569A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF15; TL1A; TNF Superfamily Member 15; Vascular Endothelial Growth Inhibitor-192A; Vascular Endothelial Cell Growth Inhibitor; Vascular Endothelial Growth Inhibitor; TNF Ligand-Related Molecule 1; TNF Superfamily Ligand TL1A; VEGI; MGC129934; TL1; MGC129935; Tumor Necrosis Factor (Ligand) Superfamily, Member 15; Tumor Necrosis Factor Superfamily Member 15; Tumor Necrosis Factor Ligand Superfamily Member 15; Tumor Necrosis Factor Ligand 1B; VEGI192A; TNLG1B
Species:
Human
Source:
HEK293
Cat. No.: HY-P990876A
Synonyms: PF-06480605; RVT-3101
Target:
Research Areas:
Afimkibart (PF-06480605; RVT-3101) is a humanized monoclonal antibody targeting TL1A (TNFSF15). Afimkibart blocks the TL1A‑DR3 signaling axis by neutralizing the TL1A ligand, inhibits the release of pro-inflammatory cytokines, suppresses NF-κB activation and IFN-γ production, and simultaneously attenuates fibroblast activation and fibrosis progression associated with this pathway. Afimkibart is applicable to research on immune inflammation-related conditions, such as ulcerative colitis [1] .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
