138 Results for "

Xanthone

" in MedChemExpress (MCE) Product Catalog:
Products (138)

138 Results for "Xanthone" in MCE Product Catalog:

11
alpha-Mangostin
alpha-Mangostin
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11 Publications Verification
Cat. No.: HY-N0328
CAS No.: 6147-11-1
Synonyms: α-Mangostin
Category:  

other families Xanthones Phenols Polyphenols Plants Disease Research Fields Cancer

Target:  

Reactive Oxygen Species (ROS) Apoptosis Bacterial Fungal Virus Protease

alpha-Mangostin (α-Mangostin) is a dietary xanthone with broad biological activities, such as antioxidant, anti-allergic, antiviral, antibacterial, anti-inflammatory and anticancer effects. It is an inhibitor of mutant IDH1 (IDH1-R132H) with a Ki of 2.85 μM.
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Isomangiferin
Isomangiferin
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4 Cited Publications
Cat. No.: HY-N0772
CAS No.: 24699-16-9
Category:  

Infection Liliaceae Xanthones Phenols Polyphenols Anemarrhena asphodeloides Bunge Plants Disease Research Fields

Target:  

VEGFR NOD-like Receptor (NLR) NF-κB Bacterial AMPK Acetyl-CoA Carboxylase Apoptosis Reactive Oxygen Species (ROS) HSV Drug Derivative

Isomangiferin is an orally active xanthone C-glucoside, and its chemical structure is similar to Mangiferin (HY-N0290). Isomangiferin is an effective VEGFR-2 kinase inhibitor, which can induces cell apoptosis, inhibit the growth, metastasis and angiogenesis of breast cancer. Isomangiferin exerts anti-inflammatory effects by inhibiting the HMGB1/NLRP3/NF-κB signaling pathway, thereby improving the renal function indicators of diabetic mice. Isomangiferin exhibits inhibitory effects on various bacteria and herpes simplex virus type 1 (HSV-1). Isomangiferin promotes the migration and osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) and reduces cell apoptosis and the production of ROS by activating the AMPK/ACC pathway, thereby facilitating fracture healing .
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beta-Mangostin
beta-Mangostin
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4 Cited Publications
Cat. No.: HY-N0941
CAS No.: 20931-37-7
Synonyms: β-Mangostin
Category:  

Infection Xanthones Guttiferae Garcinia mangostana Linn. Phenols Polyphenols Plants Disease Research Fields Cancer

Target:  

Bacterial Parasite Apoptosis

beta-Mangostin (β-Mangostin) is a xanthone compound present in Cratoxylum arborescens, with antibacterial and antimalarial activities. beta-Mangostin exhibits antimycobacterial activity against Mycobacterium tuberculosis with an MIC of 6.25 μg/mL. beta-Mangostin possesses in vitro antimalarial activity against Plasmodium falciparum, with an IC50 of 3.00 μg/mL. beta-Mangostin has potent anticancer activity against various cancers (such as hepatocellular carcinoma, leukaemic) .
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3
Xanthone
Xanthone
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3 Cited Publications
Cat. No.: HY-N0126
CAS No.: 90-47-1
Category:  

Infection Xanthones Guttiferae Garcinia mangostana Linn. Phenols Plants Disease Research Fields Inflammation/Immunology

Target:  

Environmental Pollutants Calcium Channel Monoamine Oxidase

Xanthone is a monoamine oxidase A (MAO-A) inhibitor with an IC50 of 0.84 µM. Xanthon inhibits Norepinephrine (HY-13715) and high-K +-induced vasoconstriction with IC50 values of 60.26 μM and 82.9 μM, respectively. Xanthon increases intracellular cyclic adenosine 3′,5′-monophosphate (cAMP) content and blocks Ca 2+ channels. Xanthone is the scaffold of several pharmacologically active compounds .
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2
Garcinone C
Garcinone C
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2 Cited Publications
Cat. No.: HY-N6954
CAS No.: 76996-27-5
Category:  

other families Xanthones Garcinia oblongifolia Champ. ex Benth. Guttiferae Phenols Polyphenols Plants Disease Research Fields Cancer

Target:  

ATM/ATR STAT CDK Hedgehog

Garcinone C, a xanthone derivative, is a natural compound extracted from Garcinia oblongifolia that is used as an anti-inflammatory, astringency and granulation-promoting medicine, and has potential cytotoxic effects on certain cancers. Garcinone C stimulates the expression levels of ATR and 4E-BP1, arrests the cell cycle, inhibits cell viability of the human Nasopharyngeal carcinoma (NPC) cell lines CNE1, CNE2, HK1 and HONE1 in a time‑ and dose‑dependent manner through inhibition of Hedgehog signaling pathway. Garcinone C is orally active .
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1
3,6-Dihydroxyxanthone
3,6-Dihydroxyxanthone
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1 Cited Publications
Cat. No.: HY-W031510
CAS No.: 1214-24-0
Target:  

Drug Derivative

Research Areas:  

Cancer

3,6-Dihydroxyxanthone (compound 3) is a xanthone derivatives. 3,6-Dihydroxyxanthone (compound 3) has anticancer activity. 3,6-Dihydroxyxanthone (compound 3) can be used for cancer research .
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1
1,3,5,8-Tetrahydroxyxanthone
1,3,5,8-Tetrahydroxyxanthone
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1 Cited Publications
Cat. No.: HY-N2050
CAS No.: 2980-32-7
Synonyms: Desmethylbellidifolin
Category:  

Neurological Disease Xanthones Plants other families Gentianaceae Phenols Polyphenols Swertia chirata Disease Research Fields Inflammation/Immunology

Target:  

Others

1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin) is a natural xanthone extracted from Swertia chirata. 1,3,5,8-Tetrahydroxyxanthone has antispasmodic effect and anti-inflammatory activity .
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1
Swertianolin
Swertianolin
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1 Cited Publications
Cat. No.: HY-N2192
CAS No.: 23445-00-3
Category:  

Xanthones Gentianaceae Swertia bimaculata (Sieb. et Zucc.) Hook. f. et Thoms. ex C. B. Clark Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology

Target:  

Bacterial p38 MAPK NF-κB NO Synthase Reactive Oxygen Species (ROS)

Swertianolin is a xanthone glycoside. Swertianolin can be isolated from plants of the Gentianaceae family (e.g., Gentiana campestris and Swertia punicea). Swertianolin inhibits p38 phosphorylation and NF-κB activation, and reduces NO and ROS production. Swertianolin exhibits anti-Helicobacter pylori activity with an IC50 of 6.1 μM and a minimum bactericidal concentration of 91.7 μM. Swertianolin modulates immune function in sepsis. Swertianolin is useful in the research of diseases such as Alzheimer's disease, hepatitis B, Helicobacter pylori infection, and sepsis .
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Macurin
Macurin
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Cat. No.: HY-N3347
CAS No.: 519-34-6
Synonyms: Maclurin
Category:  

Garcinia lancilimba C. Y. Wu ex Y. H. Li Guttiferae Phenols Polyphenols Plants

Target:  

Others

Macurin is a xanthone that can be isolated from Garcinia lancilimba .
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9-Hydroxycalabaxanthone
9-Hydroxycalabaxanthone
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Cat. No.: HY-N2795
CAS No.: 35349-68-9
Synonyms: Xanthone I
Target:  

Parasite Bacterial

Research Areas:  

Infection

9-Hydroxycalabaxanthone (Xanthone I) is a known xanthone isolated from Garcinia mangostana Linn. 9-Hydroxycalabaxanthone has quorum-sensing inhibitory, anti-microbial, and anti-malarial activities (IC50=1.2-1.5 μM) .
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Euxanthone
Euxanthone
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Cat. No.: HY-N3883
CAS No.: 529-61-3
Category:  

Flavonoids Garcinia oblongifolia Champ. ex Benth. Guttiferae Plants Other Flavonoids

Target:  

Autophagy

Euxanthone, a xanthone derivative, attenuates Aβ1-42-induced oxidative stress and apoptosis by triggering autophagy. Euxanthone exhibits anti-neoplastic and neuroprotective activities .
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Garcinone E
Garcinone E
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Cat. No.: HY-123901
CAS No.: 112649-21-5
Purity:  98.19%
Category:  

Flavonoids Guttiferae Garcinia mangostana Linn. Plants Other Flavonoids

Target:  

Apoptosis

Garcinone E is a natural xanthone found in the rind of the mangosteen fruit. Garcinone E induces apoptosis and inhibits cancer cell migration. Garcinone E has anticancer effects on different human cancer cell lines, including colorectal, breast, and hepatocellular carcinomas .
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R-30-Hydroxygambogic acid
R-30-Hydroxygambogic acid
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Cat. No.: HY-N10678
CAS No.: 881027-35-6
Category:  

Ketones, Aldehydes, Acids Guttiferae Plants Garcinia hanburyi Hook. f.

Target:  

Others

R-30-Hydroxygambogic acid is polyprenylated xanthone epimer that can be isolated from gamboges of Garcinia hanburyi. R-30-Hydroxygambogic acid shows cytotoxicities to Human Leukemia K562 cell lines of IC50 values of 2.89 and 1.27 μM for K562/R and K562/S, respectively. R-30-Hydroxygambogic acid can be used for the research of cancer .
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Cowaxanthone B
Cowaxanthone B
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Cat. No.: HY-N6248
CAS No.: 212842-64-3
Category:  

Infection other families Xanthones Phenols Polyphenols Plants Disease Research Fields

Target:  

Bacterial

Cowaxanthone B is a xanthone isolated from the fruits of Garcinia cowa. Cowaxanthone B has weak antibacterial activity .
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Xanthone V1a
Xanthone V1a
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Cat. No.: HY-N10985
CAS No.: 103450-96-0
Category:  

Flavonoids Maclura fruticosa (Roxburgh) Corner Plants Moraceae Other Flavonoids

Target:  

Free Radical Scavengers Drug Derivative

Xanthone V1a, a derivative of Xanthone (HY-N0126), is an antioxidant that can be found in the roots of Cudrania tricuspidata and twig extracts of Maclura fruticosa. Xanthone V1a exerts cytotoxic effects against colon, hepatocellular, and gastric carcinoma cells. Xanthone V1a exhibits scavenging activitys against DPPH and ABTS. Xanthone V1a can be used for the research of colon carcinoma, hepatocellular carcinoma, and gastric carcinoma .
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1,3,5,6-Tetrahydroxyxanthone
1,3,5,6-Tetrahydroxyxanthone
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Cat. No.: HY-N9113
CAS No.: 5084-31-1
Category:  

Flavonoids Guttiferae Hyperlcurn perforatum L. Plants Other Flavonoids

Target:  

Others

1,3,5,6-Tetrahydroxyxanthone is a natural xanthone that can be isolated from Garcinia achachairu Rusby (Clusiaceae) branches. 1,3,5,6-Tetrahydroxyxanthone induces diuresis and saluresis in normotensive and hypertensive rats .
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Isomorellic acid
Isomorellic acid
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Cat. No.: HY-N8727
CAS No.: 5262-69-1
Category:  

Ketones, Aldehydes, Acids Guttiferae Plants Garcinia hanburyi Hook. f.

Target:  

Others

Isomorellic acid is a cytotoxic caged xanthone and can be used for cancer research .
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Cudraxanthone D
Cudraxanthone D
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Cat. No.: HY-N3647
CAS No.: 96552-41-9
Category:  

Xanthones Maclura tricuspidata Carriere Phenols Plants Moraceae

Target:  

Others

Cudraxanthone D is a Xanthones product that can be isolated from the roots of Cudrania tricuspidata .
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Polygalaxanthone XI
Polygalaxanthone XI
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Cat. No.: HY-N6803
CAS No.: 857859-82-6
Category:  

Xanthones Polygalaceae Phenols Polyphenols Plants Polygala tenuifolia Willd.

Target:  

Others

Polygalaxanthone XI, a xanthone glycoside isolated from the cortexes of Polygala tenuifolia, can be used in the study of expectorant, and tranquilizing agent .
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BR-xanthone A
BR-xanthone A
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Cat. No.: HY-N2964
CAS No.: 112649-48-6
Category:  

Xanthones Guttiferae Garcinia mangostana Linn. Phenols Plants

Target:  

Others

BR-xanthone A is a xanthone that can be extracted from the dried husk of mangosteen.
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