Search Result

Results for "

acetylcholinesterase

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (10) Acyltransferase (1) Akt (5) Aldehyde Dehydrogenase (ALDH) (1) Aminotransferases (Transaminases) (1) AMPK (1) Amyloid-β (29) Angiotensin-converting Enzyme (ACE) (1) Antibiotic (5) Apoptosis (33) ATM/ATR (1) Autophagy (7) Bacterial (14) Bcl-2 Family (2) Beta-secretase (5) Biochemical Assay Reagents (4) Calcium Channel (4) CaMK (1) Carbonic Anhydrase (5) Carboxylesterase (CES) (1) Caspase (4) Cathepsin (2) CCR (1) CDK (1) Chemerin Receptor (1) Cholinesterase (ChE) (370) Complement System (1) COX (5) Cytochrome P450 (1) Dengue Virus (1) DNA/RNA Synthesis (1) Dopamine Receptor (1) Drug Derivative (8) Drug Intermediate (3) Drug Isomer (1) Drug Metabolite (7) Endogenous Metabolite (15) Environmental Pollutants (11) Epoxide Hydrolase (3) FAAH (1) FAP (1) Ferroptosis (1) Flavivirus (1) Fungal (4) G-quadruplex (1) GABA Receptor (1) Glutathione Peroxidase (1) Glycosidase (5) GnRH Receptor (1) GPR55 (2) GSK-3 (4) Heme Oxygenase (HO) (1) HIF/HIF Prolyl-Hydroxylase (3) Histamine Receptor (4) HIV (2) HSP (1) HSV (1) iGluR (7) Influenza Virus (2) Insecticide (28) Interleukin Related (7) Isotope-Labeled Compounds (20) JAK (2) JNK (5) Keap1-Nrf2 (4) Kisspeptin Receptor (3) LOX-1 (2) mAChR (7) MDM-2/p53 (1) Microtubule/Tubulin (2) Mitochondrial Metabolism (1) MMP (4) MOFs (1) Monoamine Oxidase (24) mTOR (1) Na+/K+ ATPase (1) nAChR (6) NF-κB (9) NO Synthase (4) NOD-like Receptor (NLR) (4) Notch (1) Opioid Receptor (1) P-glycoprotein (5) p38 MAPK (7) Parasite (11) PARP (1) PGE synthase (1) Phosphatase (6) PI3K (4) PKA (2) PPAR (1) PTEN (1) Reactive Oxygen Species (ROS) (21) Reference Standards (52) ROS Kinase (4) SARS-CoV (2) Ser/Thr Protease (4) Serotonin Transporter (1) Sigma Receptor (1) Sirtuin (1) SOD (4) Sodium Channel (2) STAT (3) Tau Protein (3) Telomerase (1) TGF-beta/Smad (1) TGF-β Receptor (1) Thrombopoietin Receptor (3) TNF Receptor (5) Toll-like Receptor (TLR) (1) Topoisomerase (2) Tyrosinase (1) UGT (1) VEGFR (3) Xanthine Oxidase (2) α-synuclein (1) β-glucuronidase (1) γ-secretase (2)
By Research Areas:	Cancer (60) Cardiovascular Disease (8) Endocrinology (2) Infection (57) Inflammation/Immunology (79) Metabolic Disease (30) Neurological Disease (305)
Click Chemistry:	Alkynes (3)
Oligonucleotides:	Liposomal Film-forming Agents (1) Emulsifiers (1) Solubilizing Agents (1)

440

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

146

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides

Scopoletin 4 Publications Verification Gelseminic acid; Chrysatropic acid	Cholinesterase (ChE) Apoptosis	Inflammation/Immunology
Scopoletin is an inhibitor of acetylcholinesterase (AChE).

Galanthamine 10+ Cited Publications Galantamine	Cholinesterase (ChE) Apoptosis	Neurological Disease
Galanthamine is a potent acetylcholinesterase (AChE) inhibitor with an IC₅₀ of 500 nM.

Glutathione ethyl ester	Reactive Oxygen Species (ROS)	Metabolic Disease
Glutathione ethyl ester is a cell-permeable GSH donor and provides an efficient supply of GSH to the oocyte. Glutathione ethyl ester shows positive effect on the in vitro production of embryos by enhancement of the antioxidative defense .

Acetylcholinesterase, Fly head ACHE; EC 3.1.1.7	Cholinesterase (ChE)	Neurological Disease
Acetylcholinesterase, Fly head (ACHE; EC 3.1.1.7) is a cholinergic enzyme mainly found in neuromuscular junctions and cholinergic type chemical synapses used in biochemical research. Acetylcholinesterase, Fly head catalyzes the breakdown or hydrolysis of acetylcholine and some other choline esters that act as neurotransmitters into acetate and choline. Acetylcholinesterase, Fly head's main role is to terminate neuronal transmission and signaling between synapses to prevent ACh spread and activation of nearby receptors .

Acetylcholinesterase, Electric eel	Cholinesterase (ChE)	Neurological Disease
Acetylcholinesterase, Electric eel is a cholinergic enzyme that is mainly found in neuromuscular junctions and cholinergic chemical synapses and is often used in biochemical research. Acetylcholinesterase, Electric eel can catalyze the decomposition or hydrolysis of acetylcholine and some other choline esters that act as neurotransmitters into acetic acid and choline. The main function of Acetylcholinesterase, Electric eel is to terminate neuronal transmission and signal conduction between synapses to prevent ACh diffusion and activation of nearby receptors .

Sinapine 2 Publications Verification	Cholinesterase (ChE) P-glycoprotein	Neurological Disease Inflammation/Immunology Cancer
Sinapine is an alkaloid isolated from seeds of the cruciferous species. Sinapine exhibits anti-inflammatory, anti-oxidant, anti-tumor, anti-angiogenic and radio-protective effects. Sinapine is also an acetylcholinesterase (AChE) inhibitor and can be used for the research of Alzheimer’s disease, ataxia, myasthenia gravis, and Parkinson’s disease .

Trimethylammonium chloride Hegzadesil; Trimethylamine hydrochloric acid; Trimethylamine monohydrochloride	Environmental Pollutants Cholinesterase (ChE) Endogenous Metabolite	Metabolic Disease
Trimethylammonium chloride (Hegzadesil) is a non-competitive *Acetylcholinesterase* inhibitor. Trimethylammonium chloride reversibly blocks the deacetylation of acetylcholinesterase .

Sinapine thiocyanate 2 Publications Verification	P-glycoprotein Cholinesterase (ChE)	Cancer
Sinapine thiocyanate is an alkaloid isolated from seeds of the cruciferous species. Sinapine thiocyanate exhibits anti-inflammatory, anti-oxidant, anti-tumor, anti-angiogenic and radio-protective effects. Sinapine thiocyanate is also an acetylcholinesterase (AChE) inhibitor and can be used for the research of Alzheimer’s disease, ataxia, myasthenia gravis, and Parkinson’s disease .

Obidoxime dichloride	Cholinesterase (ChE)	Neurological Disease
Obidoxime dichloride is a non-full spectrum oxime agent and can be used as an antidote for organophosphate nerve agent poisoning. Obidoxime dichloride reactivates sarin-inhibited acetylcholinesterase (AChE) and reduces acute toxicity of sarin-evaluated .

Chavicol p-Hydroxyallylbenzene	Cholinesterase (ChE)	Inflammation/Immunology
Chavicol (p-Hydroxyallylbenzene) is a phenylpropane compound. Chavicol can be isolated from the bark of Sassafras tzumu. Chavicol exhibits *Acetylcholinesterase* inhibitory activity (IC₅₀ = 7.42 μM). Chavicol produces a 3% inhibitory effect on antigen-IgE-mediated degranulation in mast cells .

Trimyristin	Cholinesterase (ChE) Phosphatase	Infection Neurological Disease
Trimyristin is an orally active compound. Trimyristin can be isolated from the seeds of nutmeg (Myristica fragrans). Trimyristin inhibits the activities of acetylcholinesterase (AChE), ACP and ALP, with IC₅₀ values of 0.11, 0.16 and 0.18 mM, respectively. Trimyristin exerts competitive-noncompetitive inhibition on acetylcholinesterase, uncompetitive inhibition on ACP, and competitive/noncompetitive inhibition on ALP. Trimyristin restores the downregulated acetylcholinesterase concentration in the cerebral cortex of rats exposed to sodium arsenite. Trimyristin can be used in studies related to fascioliasis and neurotoxicity .

Vincosamide	Cholinesterase (ChE)	Inflammation/Immunology
Vincosamide, an alkaloid from Psychotria leiocarpa extract, inhibits the *acetylcholinesterase* (AChE) activity with anti-inflammatory activity .

Fosthiazate	Environmental Pollutants Cholinesterase (ChE)	Others
Fosthiazate is a broad-spectrum nematicide against various plant parasitic nematodes, including Meloidogyne spp., Globodera spp., and Pratylenchus spp., through inhibiting the synthesis of acetylcholinesterase .

Kaempferol-3,7-di-O-β-glucoside Kaempferol 3,7-diglucoside	Glycosidase Cholinesterase (ChE)	Neurological Disease
Kaempferol-3,7-di-O-β-glucoside (Kaempferol 3,7-diglucoside), a flavonol, possesses enzyme inhibition property towards α-amylase, α-glucosidase and *Acetylcholinesterase*. Kaempferol-3,7-di-O-β-glucoside protects differentiating neuronal cells, SH-SY5Y from Amyloid β peptide-induced injury. Kaempferol-3,7-di-O-β-glucoside has the potential for Alzheimer's research .

Phenoxyacetone Phenoxy-2-propanone	Cholinesterase (ChE)	Others
Phenoxyacetone is a competitive acetylcholinesterase (AChE) inhibitor .

Pitofenone hydrochloride	Cholinesterase (ChE)	Neurological Disease
Pitofenone hydrochloride, a spasmolytic compound, inhibits the *acetylcholinesterase* (AChE) activity from bovine erythrocytes and from electric eel with K_is of 36 and 45 μM, respectively .

Fenchlorphos 1 Publications Verification	Environmental Pollutants Parasite Cholinesterase (ChE)	Infection
Fenchlorphos, an organophosphate, is an insecticide. Fenchlorphos is an inhibitor of the enzyme acetylcholinesterase (AChE). Fenchlorphos is able to cause mitochondrial dysfunction .

N-Boc-4-piperidinemethanol	Cholinesterase (ChE) Drug Intermediate	Others
N-Boc-4-piperidinemethanol (Compound 4) is a synthetic intermediate. N-Boc-4-piperidinemethanol can be used for the preparation of *Acetylcholinesterase* inhibitors .

Trimethylammonium chloride (Standard) Hegzadesil (Standard); Trimethylamine hydrochloric acid (Standard); Trimethylamine monohydrochloride (Standard)	Endogenous Metabolite Cholinesterase (ChE) Reference Standards	Metabolic Disease
Trimethylammonium chloride (Standard) is the analytical standard of Trimethylammonium chloride. This product is intended for research and analytical applications. Trimethylammonium chlorideIt is an endogenous metabolite that inhibits deacetylation. Trimethylammonium chlorideIs a non-competitive inhibitor of acetylcholinesterase .

Aβ1–42 aggregation inhibitor 1	Cholinesterase (ChE) Amyloid-β	Neurological Disease
Aβ1-42 aggregation inhibitor 1 inhibits AChE (acetylcholinesterase) and BuChE (butyrylcholinesterase) with the IC₅₀ value of 2.64 μM and 1.29 μM, respectively. Aβ1-42 aggregation inhibitor 1 inhibits self-mediated Aβ1-42 aggregation by 51.29% at a concentration of 25 μM. Aβ1-42 aggregation inhibitor 1 has the potential for the research of anti-Alzheimer's disease .

1-Hexacosanol Ceryl Alcohol	Biochemical Assay Reagents	Infection
1-Hexacosanol can be used as an inhibitor of acetylcholinesterase (AChE). 1-Hexacosanol has larvicidal activity and can inhibit the acetylcholinesterase activity of Culex quinquefasciatus, Aedes aegypti and Chironomus riparius, exerting neurotoxic effects .

Fasciculin-II Fas-2	Cholinesterase (ChE)	Neurological Disease
Fasciculin-II (Fas-2) is a potential inhibitor of acetylcholinesterase (AChE) .

AChE-IN-23	Cholinesterase (ChE)	Neurological Disease
AChE-IN-23 (compound 3h) is an acetylcholinesterase (AChE) inhibitor with an IC₅₀ value of 48.3 μM .

Donepezil N-oxide	Cholinesterase (ChE) Drug Metabolite	Neurological Disease
Donepezil N-oxide, a metabolite of Donepezil (HY-14566), is human erythrocyte acetylcholinesterase (AChE) inhibitor .

Azamethiphos	Environmental Pollutants Cholinesterase (ChE) Insecticide	Infection Neurological Disease
Azamethiphos is an *acetylcholinesterase* inhibitor and insecticide. Azamethiphos covalently binds to acetylcholinesterase via phosphorylation, inhibits its activity, causes acetylcholine to accumulate in cholinergic synapses, triggers uncontrolled excitation of cholinergic sites, induces paralysis and leads to death. Azamethiphos can be used as a bath insecticide in salmonid aquaculture to control sea lice infestations, and it exerts acute toxicity to European lobster larvae, including mortality and movement disorders .

Minaprine	Monoamine Oxidase Cholinesterase (ChE)	Neurological Disease
Minaprine is a brain-penetrant monoamine oxidase inhibitor. Minaprine also weakly inhibits *acetylcholinesterase* (AChE) activity. Minaprine reduces intraneuronal dopamine metabolism, lowers striatal homovanillic acid and dihydroxyphenylacetic acid levels, and raises striatal 3-methoxytyramine and 5-hydroxytryptamine levels. Minaprine exhibits convulsant, antidepressant properties .

AChE/Nrf2 modulator 1	Cholinesterase (ChE) Keap1-Nrf2	Neurological Disease
AChE/Nrf2 modulator 1 is an orally active acetylcholinesterase (AChE)/nuclear factor erythroid 2-related factor 2 (Nrf2) modulator. AChE/Nrf2 modulator 1 has Nrf2 inductive activity and AChE inhibitory activity for eeAChE and hAChE with IC₅₀ values of 0.07 μM and 0.38 μM, respectively. AChE/Nrf2 modulator 1 can be used for the research of Alzheimer's disease .

Lycoramine	Cholinesterase (ChE)	Neurological Disease
Lycoramine, a dihydro-derivative of galanthamine, is isolated from Lycoris radiate. Lycoramine is a potent acetylcholinesterase (AChE) inhibitor .

Linarin (Standard) Buddleoside (Standard); Linarine (Standard)	TNF Receptor Reference Standards Cholinesterase (ChE) PKA Apoptosis Bacterial HIV Influenza Virus	Infection Neurological Disease Inflammation/Immunology Cancer
Linarin (Standard) is the analytical standard of Linarin. This product is intended for research and analytical applications. Linarin (Buddleoside) is an orally active and selective inhibitor of acetylcholinesterase (AChE). Linarin has many activities, such as anti-inflammatory, antioxidant, sleep aid and sedation, bone differentiation, anti-tumor, antibacterial and antiviral. Linarin can be used to study diseases such as the nervous system, osteoporosis and cancer.

TAK-802	Cholinesterase (ChE)	Neurological Disease
TAK-802 is an orally active and potent *acetylcholinesterase* inhibitor. TAK-802’s distribution in red blood cells has a significant concentration dependence, with the distribution ratio decreasing as the concentration increases. TAK-802 exhibits significant nonlinear pharmacokinetic behavior .

Huperzine C	Cholinesterase (ChE)	Neurological Disease
Huperzine C is an alkaloid isolated from Huperzia serrate. Huperzine C is an acetylcholinesterase (AChE) inhibotor, with an IC₅₀ of 0.6 μM. Huperzine C can be used for the research of Alzheimer’s disease .

TZ3O	Cholinesterase (ChE) Apoptosis Caspase	Neurological Disease
TZ3O is an anticholinergic agent with neuroprotective effects. TZ3O inhibits acetylcholinesterase (AChE) activity in human plasma with an IC₅₀ of 304.5 μM. TZ3O can improve memory impairment and cognitive decline in rats in the Scopolamine (HY-N0296)-induced Alzheimer-type model. TZ3O could be used in Alzheimer’s research .

Sinapine (Standard)	Reference Standards Cholinesterase (ChE) P-glycoprotein	Neurological Disease Inflammation/Immunology Cancer
Sinapine is an alkaloid isolated from seeds of the cruciferous species. Sinapine exhibits anti-inflammatory, anti-oxidant, anti-tumor, anti-angiogenic and radio-protective effects. Sinapine is also an acetylcholinesterase (AChE) inhibitor and can be used for the research of Alzheimer’s disease, ataxia, myasthenia gravis, and Parkinson’s disease .

AP2238	Cholinesterase (ChE) Amyloid-β	Neurological Disease
AP2238 is a dual-function acetylcholinesterase (AChE) inhibitor with K_i values for human AChE (HuAChE) and butyrylcholinesterase (BuChE) of 21.7 and 48.9 μM respectively. AP2238 blocks the pro-fibrotic interaction between the peripheral site of AChE and Aβ, and can inhibit Aβ aggregation. AP2238 can be used for the research of Alzheimer's disease .

BGC-201259 RS-1259	Cholinesterase (ChE) Serotonin Transporter 5-HT Receptor Calcium Channel Sodium Channel Sigma Receptor	Neurological Disease
BGC-201259 (RS-1259) is an orally active inhibitor that simultaneously targets acetylcholinesterase (AChE) (IC₅₀ = 101 nM) and serotonin transporter (SERT) (IC₅₀ = 42 nM). BGC-201259 inhibits 5-HT receptor with an IC₅₀ of 90 nM. BGC-201259 exhibits strong weak activity against the NA transporter (IC₅₀ = 7.7 μM), L-type calcium channel (IC₅₀ = 3.6 μM), σ receptor (IC₅₀ = 2 μM), and sodium channel (IC₅₀ = 5.1 μM). BGC-201259 demonstrates synergistic potential in improving cognitive and emotional symptoms by balancing the inhibition of these two targets. BGC-201259 can be used in research on Alzheimer's disease .

Eseroline	Opioid Receptor Cholinesterase (ChE) Drug Metabolite nAChR	Neurological Disease
Eseroline is a potent μ-opioid receptor agonist, which is the hydrolytic metabolite of Physostigmine (HY-N6608). Eseroline is a selective and competitive acetylcholinesterase (AChE) inhibitor, with its K_i values for AChE and BuChE being 0.1 μM and 200 μM respectively. Eseroline has nicotinic acetylcholine receptor allosteric enhancing ligand (nAChR-APL) activity, meaning it does not activate the receptor but significantly enhances the signal transduction of Ach triggered by the receptor. Eseroline is neurotoxic, causing cell membrane damage (LDH leakage) and energy metabolism collapse (ATP depletion). Eseroline can be used for the study of Alzheimer's disease .

Eseramine	Cholinesterase (ChE)	Neurological Disease Inflammation/Immunology
Eseramine is a weak *acetylcholinesterase* inhibitor with an IC₅₀ value of 9300 nM. Eseramine is promising for research of diseases involving the regulation of acetylcholinesterase, such as glaucoma, myasthenia gravis, and protection against organophosphate poisoning .

Osmanthuside B	Cholinesterase (ChE)	Neurological Disease
Osmanthuside B can be isolated from Pseuderanthemum carruthersii (Seem.) Guill. var. atropurpureum (Bull.) Fosb and has weak acetylcholinesterase inhibitory activity .

Paecilomide	Cholinesterase (ChE)	Others
Paecilomide is a pyridone alkaloid and *acetylcholinesterase* inhibitor .

Cythioate	Cholinesterase (ChE)	Neurological Disease
Cythioate is an organophosphorous insecticide and anthelmintic. Cythioate is an *acetylcholinesterase* inhibitor which interferes with neuromuscular transmission in ectoparastites .

KR-27425	Endogenous Metabolite	Neurological Disease
AChE activator 1 (compound 13) is a non-pyridinium oxime reactivator of paraoxon-inhibited *acetylcholinesterase(AChE)* .

Samioside	Cholinesterase (ChE)	Infection Inflammation/Immunology
Samioside is an effective *acetylcholinesterase* inhibitor that can be isolated from Phlomis nissolii and P. capitata. Samioside possesses free-radical scavenging and antimicrobial activities. Samioside can be used in research on its anti-Alzheimer’s potency .

Fosthiazate (Standard)	Cholinesterase (ChE) Reference Standards	Others
Fosthiazate (Standard) is the analytical standard of Fosthiazate. This product is intended for research and analytical applications. Fosthiazate is a broad-spectrum nematicide against various plant parasitic nematodes, including Meloidogyne spp., Globodera spp., and Pratylenchus spp., through inhibiting the synthesis of acetylcholinesterase .

Heliosupine	Cholinesterase (ChE)	Others
Heliosupine is a pyrrolizidine alkaloid. Heliosupine is an acetylcholinesterase (AChE) inhibitor, with an IC₅₀ 0.57 mM. Heliosupine exhibits deterrent effects against generalist herbivores .

Stemoninine	Cholinesterase (ChE)	Neurological Disease Inflammation/Immunology
Stemoninine is a lycoris alkaloid that can be used as an antitussive. Stemoninine has significant inhibitory activity against human acetylcholinesterase (AChE) (IC₅₀=5.52 μM) .

Quinolactacin A1	Cholinesterase (ChE)	Neurological Disease
Quinolactacin A1 is a potent *acetylcholinesterase* (AChE) inhibitor from solid state fermentation of Penicillium citrinum 90648. Quinolactacin A1 can be used for the research of Alzheimer disease .

Cat. No.	Product Name	Type

HY-103373

PE154	Fluorescent Dyes
PE154 (Compound 13) is a potent fluorescent inhibitor of human *acetylcholinesterase* (AChE) and butyrylcholinesterase (BChE) (IC₅₀s=280 pM and 16 nM, respectively) . PE154 can label β-amyloid plaques in histochemical analysis .

Cat. No.	Product Name	Type

HY-D0837

Imidazole

2 Publications Verification

Glyoxaline; 1,3-Diaza-2,4-cyclopentadiene

Biochemical Assay Reagents

Imidazole (Glyoxaline; 1,3-Diaza-2,4-cyclopentadiene) is a heterocyclic aromatic compound. Imidazole bearing molecules have been used as corrosion, acetylcholinesterase (AChEI) and xanthine oxidase (XO) inhibitors, performing biological activities such as antifungal, antituberculosis, anti-inflammatory, antioxidant, and analgesic, amongst many others. Imidazole inhibits the enzymatic conversion of the endoperoxides (PGG₂ and PGH₂) to thromboxane A2 by platelet microsomes. Imidazole derivatives exhibits inhibition on SARS-CoV-2 3CL ^Pro enzyme, which is promising for research in the field of Alzheimer’s disease, gout, COVID-19 and thrombo-embolic disease .

HY-21629

N-Boc-4-piperidinemethanol	Biochemical Assay Reagents
N-Boc-4-piperidinemethanol (Compound 4) is a synthetic intermediate. N-Boc-4-piperidinemethanol can be used for the preparation of *Acetylcholinesterase* inhibitors .

HY-W127493

1-Hexacosanol Ceryl Alcohol	Biochemical Assay Reagents
1-Hexacosanol can be used as an inhibitor of acetylcholinesterase (AChE). 1-Hexacosanol has larvicidal activity and can inhibit the acetylcholinesterase activity of Culex quinquefasciatus, Aedes aegypti and Chironomus riparius, exerting neurotoxic effects .

HY-D0837R

Imidazole (Standard)

Glyoxaline (Standard); 1,3-Diaza-2,4-cyclopentadiene (Standard)

Biochemical Assay Reagents

Imidazole (Standard) is the analytical standard of Imidazole. This product is intended for research and analytical applications. Imidazole (Glyoxaline; 1,3-Diaza-2,4-cyclopentadiene) is a heterocyclic aromatic compound. Imidazole bearing molecules have been used as corrosion, acetylcholinesterase (AChEI) and xanthine oxidase (XO) inhibitors, performing biological activities such as antifungal, antituberculosis, anti-inflammatory, antioxidant, and analgesic, amongst many others. Imidazole inhibits the enzymatic conversion of the endoperoxides (PGG2 and PGH2) to thromboxane A2 by platelet microsomes. Imidazole derivatives exhibits inhibition on SARS-CoV-2 3CLPro enzyme, which is promising for research in the field of Alzheimer’s disease, gout, COVID-19 and thrombo-embolic disease .

HY-W127493R

1-Hexacosanol (Standard)

Ceryl Alcohol (Standard)

Biochemical Assay Reagents

1-Hexacosanol (Standard) is the analytical standard of 1-Hexacosanol. This product is intended for research and analytical applications. 1-Hexacosanol can be used as an inhibitor of acetylcholinesterase (AChE). 1-Hexacosanol has larvicidal activity and can inhibit the acetylcholinesterase activity of Culex quinquefasciatus, Aedes aegypti and Chironomus riparius, exerting neurotoxic effects.

Cat. No.	Product Name	Target	Research Area

HY-134124

Glutathione ethyl ester	Reactive Oxygen Species (ROS)	Metabolic Disease
Glutathione ethyl ester is a cell-permeable GSH donor and provides an efficient supply of GSH to the oocyte. Glutathione ethyl ester shows positive effect on the in vitro production of embryos by enhancement of the antioxidative defense .

HY-P2161B

TAK-683 acetate 4 Publications Verification	Kisspeptin Receptor	Cancer
TAK-683 acetate is a potent full KISS1 receptor (KISS1R) agonist (IC₅₀=170 pM) with improved metabolic stability. TAK-683 acetate is a nonapeptide metastin analog, exhibits agonistic activities to KISS1R with EC₅₀ values of 0.96 nM and 1.6 nM for human and rat, respectively . TAK-683 acetate depletes GnRH in the hypothalamus and reduces plasma FSH, LH, and testosterone levels in vivo, it has the potential for the study of hormone-dependent prostate cancer .

HY-P5544

M-TriDAP N-Acetylmuramyl-L-Ala-γ-D-Glu-meso-diaminopimelic acid	NOD-like Receptor (NLR)	Others
M-TriDAP (N-Acetylmuramyl-L-Ala-γ-D-Glu-meso-diaminopimelic acid) is a NOD1/2 agoist and biological active peptide .

HY-P5797

Fasciculin-II Fas-2	Cholinesterase (ChE)	Neurological Disease
Fasciculin-II (Fas-2) is a potential inhibitor of acetylcholinesterase (AChE) .

HY-P2161

TAK-683	Kisspeptin Receptor	Cancer
TAK-683 is a potent full KISS1 receptor (KISS1R) agonist (IC₅₀=170 pM) with improved metabolic stability. TAK-683 is a nonapeptide metastin analog, exhibits agonistic activities to KISS1R with EC₅₀ values of 0.96 nM and 1.6 nM for human and rat, respectively . TAK-683 depletes GnRH in the hypothalamus and reduces plasma FSH, LH, and testosterone levels in vivo, it has the potential for the study of hormone-dependent prostate cancer .

HY-P2424

Cholecystokinin-J CCK-J	Calcium Channel	Others
Cholecystokinin-J (CCK-J), a cholecystokinin, stimulates Ca ²⁺ release .

HY-P2115

Ramorelix	GnRH Receptor	Cancer
Ramorelix is a luteinizing-hormone-releasing hormone (LHRH) antagonist. Ramorelix can inhibit tumor progression in vivo. Ramorelix can be studied in anti-cancer research .

HY-P5798

Fasciculin-I FAS-I	Cholinesterase (ChE)	Neurological Disease
Fasciculin-I is isolated from the mambas venom. Fasciculin-I exerts its toxic effects by inhibiting *acetylcholinesterase* (AChE). Fasciculin-I blocks α-neurotoxins of nicotinic acetylcholine receptors and cardiac toxins that interact with cell membranes .

HY-P5544A

M-TriDAP TFA N-Acetylmuramyl-L-Ala-γ-D-Glu-meso-diaminopimelic acid TFA	NOD-like Receptor (NLR)	Others
M-TriDAP (N-Acetylmuramyl-L-Ala-γ-D-Glu-meso-diaminopimelic acid) TFA is a NOD1/2 agoist and biological active peptide .

HY-P2161A

TAK-683 TFA	Kisspeptin Receptor	Cancer
TAK-683 TFA is a potent full KISS1 receptor (KISS1R) agonist (IC₅₀=170 pM) with improved metabolic stability. TAK-683 TFA is a nonapeptide metastin analog, exhibits agonistic activities to KISS1R with EC₅₀ values of 0.96 nM and 1.6 nM for human and rat, respectively . TAK-683 TFA depletes GnRH in the hypothalamus and reduces plasma FSH, LH, and testosterone levels in vivo, it has the potential for the study of hormone-dependent prostate cancer .

Cat. No.	Product Name	Target	Research Area	Image

HY-P992076

Anti-Candida auris β-1, 3 glucans Antibody (2G8)	TGF-β Receptor TGF-beta/Smad Cholinesterase (ChE) Fungal	Infection Cancer
Anti-Candida auris β-1,3-glucans Antibody (2G8) is an antibody targeting Candida auris β-1,3-glucans, and also acts as an inhibitor of AChE and TGF-β receptor 2. Anti-Candida auris β-1,3-glucans Antibody (2G8) also targets fungal cell wall components, effectively inhibits fungal growth and interferes with capsule formation, thereby significantly reducing the fungal load in mouse tissues. Anti-Candida auris β-1,3-glucans Antibody (2G8) not only blocks TGF-β receptor binding to inhibit the Smad signaling pathway, reduces fibroblast activation and collagen deposition, but also induces epithelial differentiation of tumor cells and reduces pancreatic tumor metastasis. Anti-Candida auris β-1,3-glucans Antibody (2G8) specifically binds to the conserved N-linked glycoepitope on AChE to inhibit its activity without interfering with BChE, and can be used in studies of cryptococcosis and related tumor mechanisms .The isotype control is Human IgG1 kappa, Isotype Control (HY-P99001).

Species:	Human (3) Mouse (1)
Tag:	His (4)
Source:	HEK293 (2) CHO (1) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P72811

	Acetylcholinesterase/ACHE Protein, Mouse (HEK293, His) acetylcholinesterase; AChE	Mouse	HEK293
	Acetylcholinesterase (ACHE) proteins exhibit multiple functions, including acetylcholinesterase activity and protein self-association. It regulates acetylcholine processing, receptor signaling and recycling. Acetylcholinesterase/ACHE Protein, Mouse (HEK293, His) is the recombinant mouse-derived Acetylcholinesterase/ACHE protein, expressed by HEK293 , with C-10*His labeled tag.

HY-P704343

	Acetylcholinesterase/ACHE Protein, Human (HEK293, His) acetylcholinesterase (Yt blood group); acetylcholinesterase; ACHE; apoptosis-related acetylcholinesterase; ARACHE; EC 3.1.1; EC 3.1.1.7; N-ACHE; Yt blood group; YT	Human	HEK293
	Acetylcholinesterase (ACHE) protein is pivotal in neurotransmission, rapidly hydrolyzing acetylcholine in the synaptic cleft to terminate signal transduction at the neuromuscular junction. Beyond neurotransmitter regulation, ACHE is implicated in neuronal apoptosis, indicating a broader role in cellular processes associated with programmed cell death. Acetylcholinesterase/ACHE Protein, Human (HEK293, His) is the recombinant human-derived Acetylcholinesterase/ACHE protein, expressed by HEK293, with C-His labeled tag.

HY-P79277

	Acetylcholinesterase/ACHE Protein, Human (CHO, His) acetylcholinesterase (Yt blood group); acetylcholinesterase; ACHE; apoptosis-related acetylcholinesterase; ARACHE; EC 3.1.1; EC 3.1.1.7; N-ACHE; Yt blood group; YT	Human	CHO
	Acetylcholinesterase (ACHE) protein is pivotal in neurotransmission, rapidly hydrolyzing acetylcholine in the synaptic cleft to terminate signal transduction at the neuromuscular junction. Beyond neurotransmitter regulation, ACHE is implicated in neuronal apoptosis, indicating a broader role in cellular processes associated with programmed cell death. Acetylcholinesterase/ACHE Protein, Human (CHO, His) is the recombinant human-derived Acetylcholinesterase/ACHE protein, expressed by CHO , with C-6*His labeled tag.

HY-P7847

	CutA Protein, Human (His) rHuProtein CutA/CUTA, His; Protein CutA; acetylcholinesterase-Associated Protein; Brain acetylcholinesterase Putative Membrane Anchor; CUTA; ACHAP; C6orf82	Human	E. coli
	CUTA protein is a trimeric membrane anchor protein of AChE and a homolog of the bacterial divalent cation chelator CutA1 protein. CUTA protein also interacts with BACE1 and inhibits APP beta processing and Aβ production. CutA Protein, Human (His) is the recombinant human-derived CutA protein, expressed by E. coli , with C-6*His labeled tag.

Compare Products


Products	In-stock - + Add to Cart
Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
Biological Activity
Appearance
Formulation
Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Host:	Mouse (1) Rat (1) Rabbit (1)
Reactivity:	Human (1) Rat (3) Mouse (3) Monkey (1)
Application:	IHC-P (2) IHC-F (2) WB (3) FC (1)
Isotype:	IgG (1) IgG1 (1)
Conjugation:	Non-conjugated (3)
Clonality:	Monoclonal (2) Recombinant (1)
Modification:	Unmodified (2)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P810614

	Acetylcholinesterase Antibody (YA9876) ACEE; ACES_HUMAN; acetylcholinesterase; AChE; Apoptosis related acetylcholinesterase; ARACHE; N ACHE; N-ACHE; YT; YT blood group	WB, IHC-F, IHC-P	Mouse, Rat
	Acetylcholinesterase Antibody (YA9876) is a Rabbit-derived and non-conjugated IgG Recombinant, Monoclonal antibody, targeting to Acetylcholinesterase.

HY-P86779

	Acetylcholinesterase Antibody (YA6472) ACEE antibody; ACES_HUMAN antibody; acetylcholinesterase antibody; AChE antibody; Apoptosis related acetylcholinesterase antibody; ARACHE antibody; N ACHE antibody; N-ACHE antibody; YT antibody; YT blood group antibody;	WB, IHC-F	Mouse, Rat
	Acetylcholinesterase Antibody (YA6472) is a Rat -derived and non-conjugated monoclonal antibody, targeting to Acetylcholinesterase.

HY-P84186

	ACHE Antibody (YA3883) YT; ACEE; ARACHE; N-ACHE; Apoptosis related acetylcholinesterase antibody	WB, IHC-P, FC	Human, Mouse, Monkey, Rat
	ACHE Antibody (YA3883) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ACHE.

Compare Products


Products	In-stock - + Add to Cart
Cat. No.
Host
Reactivity
Application
Dilution Ratio
Molecular Weight
Conjugation
Clonality
Immunogen
Appearance
Isotype
Gene ID
SwissProt ID
Purity
Formulation
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name		Classification

HY-10400

Ladostigil hemitartrate TV-3326 hemitartrate		Alkynes
Ladostigil (TV-3326) hemitartrate is an orally active dual inhibitor of *cholinesterase* and brain-selective monoamine oxidase (MAO) that can cross the blood-brain barrier, with IC₅₀s of 37.1 and 31.8 μM for MAO-B and AChE, respectively. Ladostigil hemitartrate exhibits neuroprotective, antioxidant and anti-inflammatory activities. Ladostigil hemitartrate can be used for the research of depression and Alzheimer's disease . Ladostigil (hemitartrate) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-10399A

Ladostigil hydrochloride TV-3326 hydrochloride		Alkynes
Ladostigil (TV-3326) hydrochloride is an orally active dual inhibitor of *cholinesterase* and brain-selective monoamine oxidase (MAO), with IC₅₀s of 37.1 and 31.8 μM for MAO-B and AChE, respectively. Ladostigil hydrochloride exhibits neuroprotective, antioxidant and anti-inflammatory activities. Ladostigil can be used for the research of depression and Alzheimer's disease . Ladostigil (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-10399

Ladostigil TV-3326		Alkynes
Ladostigil (TV-3326) is an orally active dual inhibitor of *cholinesterase* and brain-selective monoamine oxidase (MAO), with IC₅₀s of 37.1 and 31.8 μM for MAO-B and AChE, respectively. Ladostigil exhibits neuroprotective, antioxidant and anti-inflammatory activities. Ladostigil can be used for the research of depression and Alzheimer's disease . Ladostigil is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Cat. No.	Product Name		Classification

HY-N5139

Lecithins, egg 1 Publications Verification Lecithins, egg yolk; Belovo PL 85		Emulsifiers Liposomal Film-forming Agents Solubilizing Agents
Lecithins, egg (Lecithins, egg yolk; Belovo PL 85) is an orally active natural phospholipid mixture extracted from egg yolks . Lecithins, egg inhibits the activities of acetylcholinesterase (AChE) and angiotensin-converting enzyme (ACE). Lecithins, egg exhibits antibacterial, antioxidant and anti-inflammatory activities, and helps delay cellular senescence. Lecithins, egg enhances nerve conduction, improves memory and cognitive function, and exerts positive effects on delaying neurodegenerative diseases. Lecithins, egg promotes lipid absorption and alleviates diarrhea. Lecithins, egg acts as a high-efficiency drug carrier for the preparation of targeted drug delivery systems such as liposomes .

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

acetylcholinesterase

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

NaturalProducts

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides

Natural
Products