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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
147 Results for "
acetylcholinesterase activity
" in MedChemExpress (MCE) Product Catalog:
Products (147)
147 Results for "acetylcholinesterase activity" in MCE Product Catalog:
13
13 Publications Verification
Research Areas:
α-NETA is a potent and noncompetitive choline acetyltransferase (ChA) inhibitor with an IC50 of 9 μM. α-NETA is a potent ALDH1A1 (IC50=0.04 µM) and chemokine-like receptor-1 (CMKLR1) antagonist. α-NETA weakly inhibits cholinesterase (ChE; IC50=84 µM) and acetylcholinesterase (AChE; IC50=300 µM). α-NETA has anti-cancer activity .
10
10 Cited Publications
Cat. No.: HY-W112938
CAS No.: 92739-63-4
10
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TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand. TMPyP4 tosylate inhibits the interaction between G-quadruplexes and IGF-1. TMPyP4 tosylate is a telomerase inhibitor and inhibits cancer cells proliferation. TMPyP4 tosylate is also a stabilizer of nucleic acid secondary structure and an acetylcholinesterase inhibitor. Besides, TMPyP4 tosylate has antiviral activity against SARS-CoV-2 .
6
6 Cited Publications
Cat. No.: HY-N0826
CAS No.: 18797-79-0
Corynoline is an orally active acetylcholinesterase (AChE) inhibitor with an IC50 of 30.6 μM. Corynoline exhibits multiple activities including anti-inflammatory, antinociceptive, antitumor and analgesic effects. Corynoline can be used in the research of diseases such as tumors and inflammatory pain .
6
Category:
Alkaloids Neurological Disease Anti-aging Huperziaceae Terpenoids Sesquiterpenes Pyridine Alkaloids Huperzia serrata (Thunb. ex Murray) Trevis. Plants Disease Research Fields
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3
3 Cited Publications
Synonyms: Glyoxaline; 1,3-Diaza-2,4-cyclopentadiene
2
2 Cited Publications
Cat. No.: HY-N0810
CAS No.: 41059-79-4
Category:
Liliaceae Neurological Disease Anemarrhena asphodeloides Bunge Plants Disease Research Fields Cancer Steroids
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1
1
1 Cited Publications
Cat. No.: HY-N6895
CAS No.: 40581-17-7
Category:
Flavones Plants Dendrobium officinale Kimura et Migo other families Flavonoids Orchidaceae Phenols Polyphenols Disease Research Fields Inflammation/Immunology
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1
1 Cited Publications
Research Areas:
Azamethiphos is an acetylcholinesterase inhibitor and insecticide. Azamethiphos covalently binds to acetylcholinesterase via phosphorylation, inhibits its activity, causes acetylcholine to accumulate in cholinergic synapses, triggers uncontrolled excitation of cholinergic sites, induces paralysis and leads to death. Azamethiphos can be used as a bath insecticide in salmonid aquaculture to control sea lice infestations, and it exerts acute toxicity to European lobster larvae, including mortality and movement disorders .
1
Category:
Myriophyllum spicatum L. Phenols Polyphenols Haloragaceae Plants Disease Research Fields Inflammation/Immunology
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1
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Buntanetap ((+)-Phenserine) is a selective acetylcholinesterase inhibitor. Buntanetap is a multiple neurotoxic protein translation inhibitor with oral activity, including amyloid precursor protein (APP), α-synuclein (αSYN) and huntingtin protein (HTT). Buntanetap reduces the production of β-amyloid precursor protein by blocking its mRNA translation. Buntanetap has anti-inflammatory effects and can be used in the study of Alzheimer's disease and Parkinson's disease .
1
1 Cited Publications
Cat. No.: HY-17388
CAS No.: 120786-18-7
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1
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Phosalone is an orally active, blood-brain barrier penetrant Insecticide and acaricide. Phosalone inhibits the activity of Acetylcholinesterase. Phosalone acts as a substrate for detoxifying esterases. Phosalone induces symptoms of cholinergic hyperactivity, toxic reactions, mortality, oxidative stress, and changes in pro-inflammatory protein levels, and exerts toxic effects on colonic tissues and cells. Phosalone controls pistachio psyllids. Phosalone can be used in studies related to colitis .
1
1 Cited Publications
Cat. No.: HY-N5139
CAS No.: 93685-90-6
Synonyms: Lecithins, egg yolk; Belovo PL 85
Category:
Category:
Coumarins Phenylpropanoids Plants Umbelliferae Disease Research Fields Inflammation/Immunology Bidens parviflora Willd.
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Amprolium hydrochloride is a thiamine transporter inhibitor and antiparasitic agent with oral activity and blood-brain barrier penetration. Amprolium hydrochloride blocks thiamine transport at the blood-brain barrier and intestine, and competitively inhibits thiamine pyrophosphokinase, inducing thiamine pyrophosphate deficiency and impairing carbohydrate synthesis. Amprolium hydrochloride induces oxidative stress, alters antioxidant enzyme activity, and inhibits acetylcholinesterase (AchE) activity. Amprolium hydrochloride disrupts reproductive organs and gametogenesis, and causes histopathological and ultrastructural damage to multiple organs. Amprolium hydrochloride induces thiamine deficiency, reduces body weight gain in mice, and causes psychomotor behavioral changes and nephropathy. Amprolium hydrochloride exhibits molluscicidal activity against the terrestrial snail Eobania vermiculata, and reduces the shedding of Eimeria meleagrimitis oocysts in feces and litter. Amprolium hydrochloride can be used for research on thiamine deficiency and coccidiosis .
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Alkaloids Corydalis yanhusuo W. T. Wang Plants Disease Research Fields Isoquinoline Alkaloids Papaveraceae Cancer
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Cat. No.: HY-N8290
CAS No.: 65725-11-3
Synonyms: Lactucopicrin
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
