97 Results for "

amino-thio-acrylonitriles of formula

" in MedChemExpress (MCE) Product Catalog:
Products (97)

97 Results for "amino-thio-acrylonitriles of formula" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-P2336A
Target:  

Melanocortin Receptor

Research Areas:  

Cancer

CCZ01048 TFA, a α-MSH analogue, exhibits high binding affinity to melanocortin 1 receptor (MC1R) with a Ki of 0.31 nM. CCZ01048 TFA shows rapid internalization into B16F10 melanoma cells and high in vivo stability. CCZ01048 TFA is a promising candidate for PET imaging of malignant melanoma .
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2
2 Cited Publications
Cat. No.: HY-145155
CAS No.: 144231-85-6
Purity:  98.84%
Target:  

Proteasome

Research Areas:  

Neurological Disease

Calpain-2-IN-1 (Formula 1A) is a isoform-specific calpain-2 inhibitor with Kis of 181 nM and 7.8 nM for calpain-1, and calpain-2, respectively. Calpain-2-IN-1 can be used for the research of neurodegenerative diseases and other diseases of synaptic function .
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2
2 Cited Publications
Cat. No.: HY-145471A
CAS No.: 2938991-80-9
Target:  

Deubiquitinase PARP

Research Areas:  

Cancer

KSQ-4279 (gentisate) (Compound Formula I) is a potent USP1 inhibitor and a selective PARP1 inhibitor. KSQ-4279 (gentisate) is promising for research of cancers .
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1
1 Cited Publications
Cat. No.: HY-W071746
CAS No.: 506-21-8
Synonyms: Linoelaidic acid
Linolelaidic acid (Linoelaidic acid) is an omega-6 trans fatty acid (TFA) that is an essential nutrient with oral activity. Linolelaidic acid can be added to enteral nutrition (oral), parenteral nutrition (intravenous), and infant formula. Linolelaidic acid has anti-inflammatory and anti-parasitic ((Parasite)) activities, and can induce Apoptosis. Linolelaidic acid is useful for research in infections .
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1
1 Cited Publications
Cat. No.: HY-N9448
CAS No.: 14116-68-8
Lacto-N-tetraose is the significant core structure of human milk oligosaccharides (HMOs) naturally existing in human milk. Lacto-N-tetraose is consist of galactose, N-acetylglucosamine, and glucose moieties. Lacto-N-tetraose has prebiotic effect, immune regulatory effect, anti-inflammatory effects, intestinal cell responses regulatory effect, antibacterial activity and antiviral activity. Lacto-N-tetraose has been widely added to infant formula .
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1
1 Cited Publications
Cat. No.: HY-105055
CAS No.: 77327-05-0
Purity:  99.95%
Didemnin B is a depsipeptide extracted from the marine tunicate Trididemnin cyanophorum. Didemnin B can be used for the research of cancer .
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1
1 Cited Publications
Cat. No.: HY-P10341
CAS No.: 1345835-12-2
Target:  

GCGR

Research Areas:  

Metabolic Disease

ZP3022 is a dual agonist of glucagon-like peptide-1 (GLP-1) and gastrin that has the ability to sustainably improve glycemic control. Additionally, ZP3022 can effectively increase β-cell mass, promote β-cell proliferation, and enhance the function of pancreatic islets. ZP3022 can be used in anti-diabetic research .
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Cat. No.: HY-148820
CAS No.: 2857037-70-6
Purity:  98.65%
Research Areas:  

Cancer

Br-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT (Formula V) is a agent-linker conjugate that composed of a potent topoisomerase I inhibitor and a linker to make an antibody agent conjugate (ADC), ABBV-969 .
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Cat. No.: HY-148819
CAS No.: 2857037-69-3
Purity:  98.71%
Research Areas:  

Cancer

NH2-bicyclopentane-7-MAD-MDCPT (Formula I) is a topoisomerase I (TOP1) inhibitor. NH2-bicyclopentane-7-MAD-MDCPT is applicable to the synthesis of the ADC ABBV-969. NH2-bicyclopentane-7-MAD-MDCPT is used in research on lung adenocarcinoma and melanoma .
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Cat. No.: HY-176523
CAS No.: 3018057-89-8
Target:  

Ras

Research Areas:  

Cancer

KRAS G12D inhibitor 29 (Compound Formula (I)) is an orally active and selective KRAS G12D mutant inhibitor. KRAS G12D inhibitor 29 blocks downstream signaling pathways mediated by KRAS G12D, suppressing tumor cell proliferation. KRAS G12D inhibitor 29 is promising for research of KRAS G12D mutation-related cancers (such as pancreatic cancer, lung cancer, colorectal cancer) .
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Cat. No.: HY-P4070
CAS No.: 1188379-43-2
Target:  

Insulin Receptor

Research Areas:  

Metabolic Disease

Insulin icodec is an Insulin (HY-P0035) analog that strongly but reversibly binds to albumin. Insulin icodec has long plasma half-life. Insulin icodec modulates insulin receptor activity, controls blood glucose levels, reduces HbA1c levels, and binds reversibly to human serum albumin. Insulin icodec can be used for the research of type 2 diabetes mellitus .
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Cat. No.: HY-156881
CAS No.: 2988890-20-4
Purity:  98.86%
Research Areas:  

Cancer

PARG-IN-4 (Formula (A)) is an orally available PARG inhibitor (EC50=1.9 nM) with cell membrane permeability. PARG-IN-4 can effectively inhibit tumor growth in mouse models. PARG-IN-4 can be used in cancer research .
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Cat. No.: HY-W034067
CAS No.: 7783-99-5
Silver nitrite is an inorganic compound with the chemical formula AgNO2. Silver nitrite can inhibit cell division and bacterial growth by interfering with protein synthesis .
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Cat. No.: HY-148819A
Purity:  98.46%
Research Areas:  

Cancer

NH2-bicyclopentane-7-MAD-MDCPT hydrochloride (Formula I) is a topoisomerase I (TOP1) inhibitor. NH2-bicyclopentane-7-MAD-MDCPT hydrochloride is applicable to the synthesis of the ADC ABBV-969. NH2-bicyclopentane-7-MAD-MDCPT hydrochloride is used in research on lung adenocarcinoma and melanoma .
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Cat. No.: HY-P5362
NODAGA-LM3 is a ligand that can cross the blood-brain barrier and targets somatostatin receptor SSTR2 with high affinity (IC50 = 1.3 nM). NODAGA-LM3 does not trigger the internalization of SSTR2 and can inhibit agonist-induced internalization processes. NODAGA-LM3 shows low uptake in normal tissues such as the liver and spleen, but high uptake in the lungs and blood pool. 68Ga-labeled NODAGA-LM3 can serve as a PET imaging agent for well-differentiated neuroendocrine tumors, and is applied in studies related to small cell lung cancer and well-differentiated neuroendocrine tumors .
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Cat. No.: HY-AF0005
Target:  

Others

Research Areas:  

Metabolic Disease

60 kcal% High Fat Diet is a high-fat model diet used to establish animal models of obesity and type 2 diabetes . Designed with similarities to Research Diets, Inc.formula D12492. This product comes with an authoritative third-party quality testing report.
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Cat. No.: HY-N10372
CAS No.: 1716-07-0
1,3-Dioleoyl-2-palmitoylglycerol is an important triacylglycerol in infant formulas .
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Cat. No.: HY-130797
CAS No.: 642473-95-8
Purity:  99.96%
Research Areas:  

Cancer

TLR7/8 agonist 3 (Compound II) is a potent TLR7 and TLR8 agonist, extracted from patent WO2016057618 (compound of formula (II)) .
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Cat. No.: HY-AF0001
AIN-76A is a formula of a purified diet for experimental rodents that can be easily reformulated to be used in many different types of nutrition studies. AIN-76A is typically used as a control group for drug-additive feeds. The feed ingredient meet the US AIN-76 standard .
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Cat. No.: HY-N3725
CAS No.: 65332-45-8
Demethylvestitol is a isoflavan compound that can be found in Baoyuan Decoction, a traditional Chinese medicine formula .
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