5 Results for "

antiphotoaging

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "antiphotoaging" in MCE Product Catalog:

Hydrangenol
Hydrangenol
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Cat. No.: HY-N4028
CAS No.: 480-47-7
Category:  

Anti-aging Hydrangeaceae Coumarins Cosmetic Research Phenylpropanoids Plants Disease Research Fields Inflammation/Immunology

Target:  

MMP COX Interleukin Related p38 MAPK ERK Keap1-Nrf2

Hydrangenol is an orally active antiphotoaging compound. It can be isolated from Hydrangea serrata leaves. Hydrangenol prevents wrinkle formation by reducing MMP and inflammatory cytokine expression and increasing moisturizing factors and antioxidant genes level .
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Santamarine
Santamarine
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Cat. No.: HY-N1326
CAS No.: 4290-13-5
Synonyms: Santamarin; Balchanin
Category:  

Terpenoids Magnoliaceae Sesquiterpenes Plants Disease Research Fields Inflammation/Immunology Magnolia grandiflora L.

Target:  

JNK p38 MAPK MMP NF-κB COX TNF Receptor Interleukin Related Reactive Oxygen Species (ROS) Apoptosis Mitochondrial Metabolism DNA/RNA Synthesis Keap1-Nrf2 Bcl-2 Family Caspase PARP TGF-beta/Smad

Santamarine (Santamarin; Balchanin) is a sesquiterpene lactone found in Artemisia scoparia. Santamarine shows anti-inflammatory, antioxidant, anticancer and anti-photoaging activities. Santamarine suppresses UVA-induced phosphorylation of JNK and p38 MAPK, nuclear translocation of phosphorylated c-Fos and c-Jun, and AP-1-mediated MMP-1 transcription and secretion. Santamarine suppresses NF-κB signaling, iNOS, COX-2, TNF-α, and IL-1β production. Santamarine inhibits thioredoxin reductase activity, induces ROS production, mitochondrial apoptosis, G2/M cell cycle arrest, and DNA damage, and reduces cancer cell growth. Santamarine can be used for the photoaging, inflammatory diseases and cancer .
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Thunberginol C
Thunberginol C
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Cat. No.: HY-N1151
CAS No.: 147517-06-4
Category:  

Hydrangeaceae Coumarins Phenylpropanoids Plants

Target:  

Bacterial Cholinesterase (ChE) MMP TNF Receptor

Thunberginol C is an orally active, selective, and non-competitive inhibitor of AChE and BChE, with IC50 values of 41.96 and 42.36 μM, respectively. Thunberginol C exerts cytoprotective, pro-collagen type I restorative, MMP-1 inhibitory, hyaluronic acid restorative, anti-photoaging effects in skin cells. Thunberginol C exerts neuroprotective, anxiolytic, TNF-α inhibitory, neuroinflammation inhibitory, and oxidative stress inhibitory effects. Thunberginol C can be used for the research of Alzheimer’s disease, UVB-induced skin photoaging, allergic reactions, oral bacterial infections, and stress-induced anxiety .
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DL-Syringaresinol
DL-Syringaresinol
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Cat. No.: HY-N1190
CAS No.: 1177-14-6
Synonyms: (±)-Syringaresinol
Category:  

Lignans Phenylpropanoids Plants Lauraceae Lindera akoensis Hay.

Target:  

p38 MAPK AP-1 Bacterial

DL-Syringaresinol ((±)-Syringaresinol), a lignin, inhibits UVA-induced upregulation of MMP-1 by suppressing MAPK/AP-1 signaling in human HaCaT keratinocytes and dermal fibroblasts (HDFs). DL-Syringaresinol has antiphotoaging properties against UVA-induced skin aging. DL-Syringaresinol exhibits weak antimycobacterial activity against Mycobacterium tuberculosis H37Rv .
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Ginsenoside C-Y
Ginsenoside C-Y
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Cat. No.: HY-N9389
CAS No.: 83480-65-3
Synonyms: Ginsenoside Y
Category:  

Triterpenes Microorganisms Terpenoids Metabolic Disease Disease Research Fields

Target:  

Drug Metabolite

Ginsenoside C-Y (Ginsenoside Y) is a metabolite of Ginsenoside Rb2 (HY-N0040). Ginsenoside C-Y exhibits anti-photoaging and anti-melanogenesis properties .
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