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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
chloroquine-resistant strains
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "chloroquine-resistant strains" in MCE Product Catalog:
2
Purvalanol B (NG 95) is a potent, selective, reversible and ATP-competitive inhibitor CDK, with IC50s of 6 nM, 6 nM, 9 nM, 6 nM for cdc2-cyclin B, CDK2-cyclin A, CDK2-cyclin E and CDK5-p35, respectively. Purvalanol B shows selectivity for CDK over a range of other protein kinases (IC50>1000 nM). Purvalanol B inhibits the growth a chloroquine-resistant strain of P. falciparum .
Cat. No.: HY-N2380
CAS No.: 132201-33-3
Category:
Alkaloids Other Alkaloids Taxaceae Plants Disease Research Fields Cancer Taxus wallichiana Zucc.
Target:
Cat. No.: HY-157892
CAS No.: 123580-46-1
Antimalarial agent 38 is an orally active antimalarial agent, which inhibits Plasmodium falciparum D6 strain, Chloroquine (HY-17589A)-sensitive Thai strain and Chloroquine-resistant FcB1 strain and K1 strain, with IC50s of 0.5, 13, 1 and 13 μM, respectively. Antimalarial agent 38 is non-cytotoxic for mammalian cells MCR58 (IC50 >140 μM). Antimalarial agent 38 improves the survival rate of Plasmodium yoelii nigeriensis infected mouse model .
Cat. No.: HY-W437569
CAS No.: 568-01-4
Target:
Cat. No.: HY-158721
CAS No.: 1214268-60-6
Synonyms: Marinamide
Category:
Target:
Cat. No.: HY-116552
CAS No.: 1809050-49-4
KAR425 is a potent and orally active antimalarial agent. KAR425 shows antimalarial activity against the Chloroquine-sensitive (CQS) D6, the Chloroquine-resistant (CQR) Dd2, and 7G8 strains of Plasmodium falciparum, with IC50 values of 62 nM, 55 nM, and 60 nM, respectively .
Cat. No.: HY-146769
CAS No.: 1214454-56-4
Antimalarial agent 11 (compound 1), a spirocyclic chromane, is a potent antimalarial agent. Antimalarial agent 11 exhibits excellent potency with an EC50 of 350 nM against the Chloroquine-resistant Dd2 strain. Antimalarial agent 11 has EC50s of 1.48 µM and 1.81 µM against D6 and ARC08-022 strains, respectively .
Target:
Cat. No.: HY-106515
CAS No.: 74129-03-6
Synonyms: WR228258
Tebuquine (WR228258), a 4-aminoquinoline, is a potent antimalarial agent. Tebuquine is active against the Chloroquine (HY-17589A) sensitive HB3 strain and the Chloroquine resistant K1 strain of Plasmodium falciparum with IC50s of 0.9 nM and 20.8 nM, respectively .
Cat. No.: HY-149960
CAS No.: 3043821-43-5
Antiparasitic agent-17 (compound 5u) is an orally active antiparasitic agent. Antiparasitic agent-17 inhibits Chloroquine sensitive (Pf3D7) and Chloroquine resistant (PfK1) strain with IC50s of 0.96 μM and 1.67 μM, respectively .
Cat. No.: HY-N20619
CAS No.: 475673-78-0
Target:
Cat. No.: HY-N19238
CAS No.: 84224-28-2
Target:
Cat. No.: HY-182319
CAS No.: 19634-27-6
Dehatrine is a dibenzylisoquinoline alkaloid with antiplasmodial activity. Dehatrine can be found in the Indonesian medicinal plant Beilschmiedia madang. Dehatrine is applicable to malaria-related research .
Cat. No.: HY-N12157A
CAS No.: 2760889-73-2
Noratherosperminine hydrochloride is a phenanthrene alkaloid found in the stem bark of Cryptocarya nigra .
Cat. No.: HY-181658
CAS No.: 3103602-12-3
Antimalarial agent 59 is an antimalarial agent. Antimalarial agent 59 inhibits the growth of Chloroquine (HY-17589A)-resistant FcB1 strain of Plasmodium falciparum with an IC50 of 46 nM. Antimalarial agent 59 also shows cytotoxic activity against cancer cells. Antimalarial agent 59 can be used for the researches of malaria and ovarian cancer .
Cat. No.: HY-N21998
CAS No.: 1657026-28-2
Synonyms: Quercetin-3-O-β-D-xylofuranoside
Target:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
