Wayanin
Wayanin (Quercetin-3-O-β-D-xylofuranoside) is a glycosylated flavonol active metabolite that can be isolated and extracted from Psidium acutangulum. Wayanin exhibits anti-plasmodial activity with an IC50 of 5.5 μM. Wayanin is used in malaria-related research.
For research use only. We do not sell to patients.
- CAS No.: 1657026-28-2
- Formula: C20H18O11
- Molecular Weight:434.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Cellular Effect
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Vero | IC50 |
>200 μM
|
Cytotoxicity against African Green Monkey kidney epithelial VERO cells.
Cytotoxicity against African Green Monkey kidney epithelial VERO cells.
|
27132714 |
In Vitro
Wayanin moderately inhibits the growth of chloroquine-resistant Plasmodium falciparum FcB1 strain in vitro with an IC50 of 5.5 μM[1].
Wayanin is non-cytotoxic toward VERO African Green Monkey kidney epithelial cells in vitro, with an IC50 > 200 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 1657026-28-2
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Molecular Weight 434.35
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Formula C20H18O11
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SMILES
O=C(C(O[C@@H]1O[C@@H]([C@@H]([C@H]1O)O)CO)=C(C2=CC(O)=C(C=C2)O)OC3=CC(O)=C4)C3=C4O
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Synonyms
Quercetin-3-O-β-D-xylofuranoside
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Keywords
- Wayanin
- 1657026-28-2
- Quercetin-3-O-β-D-xylofuranoside
- Endogenous Metabolite
- Parasite
- Psidium acutangulum Mart. ex DC
- antiplasmodial activity
- glycosylated flavonol
- VERO African Green Monkey kidney epithelial cells
- gHSQCAD NMR
- gHMBCAD NMR
- malaria
- quercetin-3-O-β-D-xylofuranoside
- chloroquine-resistant Plasmodium falciparum FcB1 strain
- 1H NMR
- Inhibitor
- inhibitor
- inhibit