120 Results for "

chrysophanol anthrone skeleton

" in MedChemExpress (MCE) Product Catalog:
Products (120)

120 Results for "chrysophanol anthrone skeleton" in MCE Product Catalog:

7
7 Publications Verification
Cat. No.: HY-W013636
CAS No.: 328-50-7
Synonyms: Alpha-Ketoglutaric acid; 2-Oxoglutaric acid
2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM) .
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7
7 Publications Verification
Cat. No.: HY-W013636A
CAS No.: 22202-68-2
Synonyms: Alpha-Ketoglutaric acid Sodium
2-Ketoglutaric acid Sodium (Alpha-Ketoglutaric acid Sodium) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid Sodium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid Sodium is a reversible inhibitor of tyrosinase (IC50=15 mM) .
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7
7 Publications Verification
Cat. No.: HY-W013636B
CAS No.: 71686-01-6
Calcium 2-oxoglutarate is an intermediate in the production of ATP or GTP in the Krebs cycle. Calcium 2-oxoglutarate also acts as the major carbon skeleton for nitrogen-assimilatory reactions. Calcium 2-oxoglutarate is a reversible inhibitor of tyrosinase (IC50=15 mM) .
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7
7 Publications Verification
Cat. No.: HY-W013636C
CAS No.: 997-43-3
Synonyms: Alpha-Ketoglutaric acid potassium
2-Ketoglutaric acid (Alpha-Ketoglutaric acid) (potassium) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid potassium is a reversible and orally active inhibitor of tyrosinase with an IC50 value of 15 mM. 2-Ketoglutaric acid potassium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid potassium significantly suppresses abnormal intestinal permeability, delocalization of tight junction proteins from the intestinal cells, expression of TNFα in vitro and in vivo. 2-Ketoglutaric acid potassium directly binds to TAK1, and inhibits the TRAF6-TAK1 interaction. 2-Ketoglutaric acid potassium also alleviates inflammatory bowel disease (IBD) symptoms and gut microbiota dysbiosis, evident by the improvements in the intestine length .
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6
6 Cited Publications
Cat. No.: HY-13595
CAS No.: 481-74-3
Purity:  99.77%
Synonyms: Chrysophanic acid
Chrysophanol (Chrysophanic acid) is a natural anthraquinone, which inhibits EGF-induced phosphorylation of EGFR and suppresses activation of AKT and mTOR/p70S6K.
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3
3 Cited Publications
Cat. No.: HY-N0886
CAS No.: 28371-16-6
Synonyms: Isobarbaloin
Aloin B (Isobarbaloin) is an orally active SARS-CoV-2 papain-like protease (PLpro) inhibitor with an IC50 of 16.08 μM (hydrolytic activity) and 17.51 μM (deubiquitinase activity). Aloin B is metabolized by rat intestinal flora into aloe-emodin-9-anthrone to exert laxative effects. Aloin B inhibits TPA (HY-18739)-induced ear edema, putrescine elevation, and tumor promotion in mouse skin. Aloin B can be used in research related to anti-inflammation, tumor promotion inhibition, coronavirus disease 2019 (COVID-19) and constipation .
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2
2 Cited Publications
Cat. No.: HY-N0656
CAS No.: 125-46-2
Usnic acid is a secondary metabolite of lichens with a unique dibenzofuran skeleton. Usnic acid inhibits DNA/RNA synthesis and has antibacterial activity. Usnic acid induces cell cycle arrest and apoptosis and has anticancer activity. Usnic acid inhibits RANKL-mediated osteoclast formation and function by reducing the transcriptional and translational expression of NFATc1. Usnic acid has antioxidant and anti-inflammatory activities by inhibiting lipid peroxidation and myeloperoxidase .
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2
2 Cited Publications
Cat. No.: HY-P2733B
CAS No.: 9046-28-0
Synonyms: GPO, Aerococcus viridans
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

Glycerol-3-phosphate oxidase, Aerococcus viridans (GPO, Aerococcus viridans) is a key intermediate in glycerol metabolism. Glycerol-3-phosphate oxidase is the skeleton of phospholipids in membrane lipids, and also a substrate of respiratory chain. Glycerol-3-phosphate oxidase produces electrons through oxidation .
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2 Cited Publications
Cat. No.: HY-P2733
CAS No.: 9046-28-0
Synonyms: GPO
Glycerol-3-phosphate oxidase, E. coli (GPO) is a key intermediate in glycerol metabolism. Glycerol-3-phosphate oxidase, E. coli is the skeleton of phospholipids in membrane lipids, and also a substrate in the respiratory chain. Glycerol-3-phosphate oxidase, E. coli produces electrons through oxidation. Glycerol-3-phosphate oxidase, E. coli is an enzyme with important functions in the field of biochemistry, and is widely used in medical testing and scientific research .
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1
1 Cited Publications
Cat. No.: HY-W009938
CAS No.: 90-44-8
Synonyms: Anthracen-9(10H)-one
Anthrone is an organic compound commonly used as a dye and intermediate. It can be used to make products such as pigments, dyes and fluorescent whitening agents, and is widely used in certain industrial production fields such as textile manufacturing, soap making and paper making. In addition, this compound is also used as a reagent and catalyst in some organic synthesis reactions.
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1
1 Cited Publications
Cat. No.: HY-N0829
CAS No.: 10376-48-4
Shionone is the major triterpenoid isolated from Aster tataricus, has anti-tussive, anti-inflammatory activities . Shionone possesses a unique six-membered tetracyclic skeleton and 3-oxo-4-monomethyl structure .
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1
1 Cited Publications
Cat. No.: HY-N2395
CAS No.: 13241-28-6
Chrysophanol 8-O-glucoside, from the roots of Rumex acetosa, shows moderate elastase inhibition activity .
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1
1 Cited Publications
Cat. No.: HY-N4151
CAS No.: 4839-60-5
Chrysophanein is a chrysophanol glycoside from leaves and roots of Aloe hijazensis. Chrysophanein shows a moderate cytotoxic activity against several carcinoma cells lines .
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1
1 Cited Publications
Cat. No.: HY-136473
CAS No.: 423731-64-0
Purity:  98.84%
Research Areas:  

Cancer

CTX-0124143 is a KAT6A inhibitor with a sulfonyl hydrazine skeleton .
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Cat. No.: HY-W013040
CAS No.: 290-37-9
Synonyms: 1,4-Diazine
Pyrazine (1,4-Diazine) is an aromatic nitrogen-containing heterocyclic compound with two nitrogen atoms, and is well known for its electron-deficient property. Pyrazine serves as a key pharmacophore in a variety of drugs, and also acts as the core skeleton of derivatives with anticancer, antimycobacterial, antithrombotic and anti-inflammatory activities .
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Cat. No.: HY-W016349
CAS No.: 138-60-3
Research Areas:  

Others

Chelidamic acid is a heterocyclic organic acid with a pyran skeleton. Chelidamic acid has good coordination ability with noble metal ions. Chelidamic acid is also one of the most potent inhibitors of glutamate decarboxylase, with a Ki of 33 μM.
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Cat. No.: HY-Y0135
CAS No.: 532-24-1
Target:  

Drug Intermediate

Research Areas:  

Cancer

Tropinone is an organic synthesis intermediate and a skeleton for constructing derivatives containing thiazole rings and other structures. Tropinone derivatives have anticancer activities such as inducing tumor cell apoptosis and inhibiting tyrosinase activity, and can be used in research such as anticancer drug development and tyrosinase inhibitor design .
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Cat. No.: HY-U00190
CAS No.: 20424-00-4
Synonyms: RD20000
Target:  

Bacterial

Research Areas:  

Inflammation/Immunology

Deprodone propionate (RD20000) is a corticosteroid which is obtained by esterifying with propionic acid the 17-position of the prednisolone skeleton and deoxidating its 21-position.
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Cat. No.: HY-N2920
CAS No.: 38242-02-3
Synonyms: 11-Oxo-β-amyrin
β-Amyrenonol (11-Oxo-β-amyrin), an oleanolic-type triterpenoid in licorice roots, is a precursor of Glycyrrhetinic acid. β-Amyrenonol has anti-proliferative and anti-inflammatory activities, and β-Amyrenonol could function as the skeleton for the synthesis of many triterpenoids .
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Cat. No.: HY-43470
CAS No.: 570-62-7
3α,12β-Dihydroxycholanoic acid is a dihydroxy bile acid that is detectable in healthy urine samples. 3α,12β-Dihydroxycholanoic acid carries hydroxy substituents at the 3α and 12β positions of the 5β-cholanoic acid steroid skeleton .
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