2. Search Result
Search Result
Results for "

effectively

" in MedChemExpress (MCE) Product Catalog:

1888

Inhibitors & Agonists

15

Screening Libraries

31

Fluorescent Dye

57

Biochemical Assay Reagents

95

Peptides

13

MCE Kits

63

Inhibitory Antibodies

156

Natural
Products

73

Isotope-Labeled Compounds

18

Click Chemistry

31

Oligonucleotides

2

GMP Molecules

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-131370B
    Intralipid 20%
    4 Publications Verification

    		 Biochemical Assay Reagents Cancer
    Intralipid 20% is a safe fat emulsion that can be used as a nutritional supplement. Intralipid 20% effectively inhibits the opening of the mitochondrial permeability transition pore, effectively protecting the heart from ischaemia-reperfusion injury and has some potential to modulate the innate immune response .
    Intralipid 20%
  • HY-P0278
    RGD
    Maximum Cited Publications
    8 Publications Verification

    		 Integrin Cancer
    RGD is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits specific cell responses; binds to integrins.
    RGD
  • HY-B2060A
    Tiamulin fumarate
    1 Publications Verification

    Thiamutilin fumarate

    		 Bacterial Antibiotic Infection
    Tiamulin (Thiamutilin) fumarate is a diterpenic antibiotic that is widely used in pigs and poultry for the control of infectious diseases. Tiamulin fumarate is effectively used in the study of airsacculitis, which is primarily caused by Mycoplasma spp .
    Tiamulin fumarate
  • HY-15345A
    Tetrahydrouridine
    3 Publications Verification

    THU; NSC-112907

    		 DNA/RNA Synthesis Cancer
    Tetrahydrouridine dihydrate is potent inhibitor of cytidine deaminase (CDA), which competitively blocks the enzyme's active site more effectively than intrinsic cytidine .
    Tetrahydrouridine
  • HY-B0577
    Latanoprost
    4 Publications Verification

    PHXA41

    		 Prostaglandin Receptor Cardiovascular Disease Others
    Latanoprost (PHXA41) is a prostaglandin F2α analogue and can be used for glaucoma research. Latanoprost can effectively pass through cornea and be hydrolyzed by esterase to latanoprost acid. latanoprost acid is an F-prostaglandin (FP) receptor agonist, and can effectively reduce intraocular pressure (IOP) by increasing the outflow of aqueous humor through uvea .
    Latanoprost
  • HY-134964
    CTB
    5+ Cited Publications

    		 Histone Acetyltransferase Apoptosis Neurological Disease Cancer
    CTB is a potent p300 histone acetyltransferase activator . CTB can effectively induce apoptosis in MCF-7 cells .
    CTB
  • HY-147214
    GNE-7883
    5 Publications Verification

    		 YAP Cancer
    GNE-7883 is a pan-TEAD inhibitor that blocks the association of YAP/TAZ with TEAD. GNE-7883 effectively reduces chromatin accessibility at TEAD motifs, inhibits cell proliferation in multiple cell line models, and achieves strong anti-tumor efficacy in vivo. In addition, GNE-7883 effectively overcomes intrinsic and acquired resistance to KRAS (Kirsten rat sarcoma viral oncogene homolog) G12C inhibitors in multiple preclinical models by inhibiting YAP/TAZ activation .
    GNE-7883
  • HY-B2060
    Tiamulin
    1 Publications Verification

    Thiamutilin

    		 Bacterial Antibiotic Infection
    Tiamulin (Thiamutilin) is a diterpenic antibiotic that is widely used in pigs and poultry for the control of infectious diseases. Tiamulin is effectively used in the study of airsacculitis, which is primarily caused by Mycoplasma spp .
    Tiamulin
  • HY-B1289
    Cetylpyridinium chloride monohydrate
    5+ Cited Publications

    Hexadecylpyridinium chloride monohydrate

    		 Bacterial Infection
    Cetylpyridinium chloride monohydrate is a cationic quaternary ammonium compound used in some types of mouthwashes, toothpastes, and throat and nasal sprays as an antiseptic that kills bacteria and other microorganisms. Effectively prevents plaque and reduces gingivitis.
    Cetylpyridinium chloride monohydrate
  • HY-15194
    Dimethylcurcumin
    10+ Cited Publications

    ASC-J9; GO-Y025

    		 Androgen Receptor Cancer
    Dimethylcurcumin (ASC-J9) is an androgen receptor degradation enhancer that effectively suppresses castration resistant prostate cancer cell proliferation and invasion.
    Dimethylcurcumin
  • HY-W007531
    2-Fluoro-5-iodopyridine

    		Biochemical Assay Reagents Others
    2-Fluoro-5-iodopyridine is an electrolyte additive. 2-Fluoro-5-iodopyridine can not only effectively protect the anode by forming a stable SEI film, but also convert dead lithium into active lithium. 2-Fluoro-5-iodopyridine effectively improves the performance of lithium metal batteries .
    2-Fluoro-5-iodopyridine
  • HY-112487
    Sandoz 58-035

    		Acyltransferase Endocrinology
    Sandoz 58-035 is a competitive inhibitor of cholesterol acyltransferase (ACAT). Sandoz 58-035 effectively inhibits (>98%) hormonally stimulated cholesterol esterification in cells .
    Sandoz 58-035
  • HY-131011
    Furanone C-30
    1 Publications Verification

    		 Bacterial Infection
    Furanone C-30 is a quorum sensing inhibitor. Furanone C-30 can effectively inhibit bacterial biofilm formation by S. mutans and its luxSmutant strain .
    Furanone C-30
  • HY-124704
    Chst15-IN-1
    1 Publications Verification

    		 SULT Neurological Disease
    Chst15-IN-1 is a potent reversible covalent Chst15 inhibitor. Chst15-IN-1 effectively inhibits chondroitin sulfate-E (CS-E) sulfation levels and other closely related glycosaminoglycans (GAG) sulfotransferases. Chst15-IN-1, as a selective sulfotransferase inhibitor, can diminish the inhibitory effects of chondroitin sulfate proteoglycans (CSPGs), and can be used for the stimulation of neuronal repair .
    Chst15-IN-1
  • HY-134216
    MAHMA NONOate
    1 Publications Verification

    		 Endogenous Metabolite NO Synthase Cardiovascular Disease
    MAHMA NONOate is a NO donor. MAHMA NONOate effectively inhibits platelet aggregation induced by either collagen or ADP .
    MAHMA NONOate
  • HY-P0278A
    RGD Trifluoroacetate
    Maximum Cited Publications
    8 Publications Verification

    		 Integrin Cancer
    RGD Trifluoroacetate is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits specific cell responses; RGD Trifluoroacetate binds to integrins.
    RGD Trifluoroacetate
  • HY-151379
    EM127

    		Histone Methyltransferase Cancer
    EM127 (compound 11c) is a SMYD3 covalent inhibitor with high selectivity, high affinity (KD=13 μM) and site-specificity. EM127 effectively inhibits ERK1/2 phosphorylation and reduces transcriptional regulation of SMYD3 target genes. EM127 effectively and prolongedly impairs methyltransferase activity. EM127 can be used in cancer research, particularly in SMYD3 positive tumours .
    EM127
  • HY-145668
    Cyclopentenyl uracil

    		UGT Cancer
    Cyclopentenyl uracil, a non-cytotoxic inhibitor of uridine kinase, effectively blocks the salvage of circulating uridine by host and tumor tissues in the intact mouse .
    Cyclopentenyl uracil
  • HY-15345
    Tetrahydrouridine dihydrate
    3 Publications Verification

    THU dihydrate; NSC-112907 dihydrate

    		 DNA/RNA Synthesis Cancer
    Tetrahydrouridine dihydrate (THU dihydrate) is potent inhibitor of cytidine deaminase (CDA), which competitively blocks the enzyme's active site more effectively than intrinsic cytidine.
    Tetrahydrouridine dihydrate
  • HY-122828
    PROTAC BTK Degrader-2

    		PROTACs Btk Others
    PROTAC BTK Degrader-2 is a potent BTK PROTAC degrader. PROTAC BTK Degrader-2 effectively reduces BTK protein levels .
    PROTAC BTK Degrader-2
  • HY-70035
    Otamixaban
    1 Publications Verification

    FXV673

    		 Factor Xa Cardiovascular Disease
    Otamixaban(FXV673) is a potent (Ki = 0.5 nM), selective, rapid acting, competitive and reversible fXa inhibitor that effectively inhibits both free and prothrombinase-bound fXa.
    Otamixaban
  • HY-119936
    GLPG2451

    		CFTR Autophagy Inflammation/Immunology
    GLPG2451 is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator, which effectively potentiates low temperature rescued F508del CFTR with an EC50 of 11.1 nM .
    GLPG2451
  • HY-N9794
    Isoboldine

    		Others Inflammation/Immunology
    Isoboldine is a pyridine alkaloid. Isoboldine effectively alleviates inflammation and joint destruction in collagen-induced arthritis in mice .
    Isoboldine
  • HY-B2208
    Glycol salicylate

    		Drug Derivative Others
    Glycol salicylate is a derivative of salicylic acid that effectively moisturizes the stratum corneum and improves the aesthetic appearance of the skin .
    Glycol salicylate
  • HY-12420
    JNJ-47117096 hydrochloride

    MELK-T1 hydrochloride

    		 MELK FLT3 Cancer
    JNJ-47117096 hydrochloride is potent and selective MELK inhibitor, with an IC50 of 23 nM, also effectively inhibits Flt3, with an IC50 of 18 nM.
    JNJ-47117096 hydrochloride
  • HY-W969907
    GSK3-IN-7

    		GSK-3 Others
    GSK3a-IN-38 is a groundbreaking small molecule that effectively inhibits GSK-3a activity.
    GSK3-IN-7
  • HY-135380
    Atorvastatin acetonide tert-butyl ester

    		Drug Intermediate Cardiovascular Disease
    Atorvastatin acetonide tert-butyl ester is a useful pharmaceutical intermediate in the preparation of Atorvastatin salts. Atorvastatin is an orally active HMG-CoA reductase inhibitor and has the ability to effectively decrease blood lipids .
    Atorvastatin acetonide tert-butyl ester
  • HY-125147
    A-1293201

    		NAMPT Cancer
    A-1293201 is a substrate-independent NAMPT inhibitor with antitumor activity. A-1293201 effectively reduces the total cellular NAD +/NADH (NADt) level, subsequently leading to ATP depletion and cancer cell death. In addition, A-1293201 can effectively overcome the acquired resistance mechanism of the NAMPT Y18 mutant to CHS-828 (HY-10079) .
    A-1293201
  • HY-15490A
    PF-670462

    		Casein Kinase Neurological Disease
    PF-670462 is a selective CKI ε/δ inhibitor. PF-670462 effectively regulates the phase of the circadian rhythm .
    PF-670462
  • HY-121907
    N-Palmitoyl L-alanine

    		Drug Intermediate Others
    N-Palmitoyl L-alanine is an organogelator. The granisetron organogel prepared based on N-Palmitoyl L-alanine has good biocompatibility and can effectively exert an antiemetic effect .
    N-Palmitoyl L-alanine
  • HY-N11913
    Siderin

    		Biochemical Assay Reagents Others
    Siderin is a Photosystem II inhibitor that effectively inhibits ATP synthesis and chloroplast electron transport during photosynthesis in isolated spinach. Siderin can be used in the study of plant photosynthesis .
    Siderin
  • HY-121354
    Hydracarbazine

    		Drug Derivative Cardiovascular Disease
    Hydracarbazine is a pyridazine. Hydracarbazine can effectively lower blood pressure, it can be used for the research of high blood pressure .
    Hydracarbazine
  • HY-P10360
    Tat-βsyn-degron

    		α-synuclein Neurological Disease
    Tat-βsyn-degron is an α-synuclein knockdown peptide that effectively degrades α-synuclein protein via the proteasome pathway. Tat-βsyn-degron effectively reduces α-synuclein protein levels in primary rat cortical neuron cultures. In a Parkinson's mouse toxicity model, Tat-βsyn-degron can alleviate parkinsonian toxin-induced neuronal damage and movement disorders .
    Tat-βsyn-degron
  • HY-W133934A
    EDTA magnesium disodium,99%

    		Biochemical Assay Reagents Others
    EDTA magnesium disodium, 99% is a chelating agent with the ability to effectively bind metal ions (including calcium, magnesium, and iron) and remove them from solution.
    EDTA magnesium disodium,99%
  • HY-163176
    WB518

    		STAT Inflammation/Immunology
    WB518 is a potent STAT3 inhibitor. WB518 effectively inhibits STAT3 activation and Keratin 17 expression. WB518 effectively alleviates imiquimod (HY-B0180) and TPA (HY-18739)-induced animal psoriasis by inhibiting STAT3 phosphorylation and Keratin 17 .
    WB518
  • HY-B1882
    Propazine

    		Endogenous Metabolite Others
    Propazine is a triazine herbicide that effectively manages broad-leaved weeds and annual grasses in sweet sorghum cultivation.
    Propazine
  • HY-B1874
    Metoxuron

    Dosanex; Purivel; SAN 6602; SAN 7102

    		 Endogenous Metabolite Others
    Metoxuron (Dosanex) is a phenylurea herbicide that effectively targets and controls annual grasses and broadleaf weeds in wheat, barley, and carrot crops.
    Metoxuron
  • HY-D1173
    Acid blue 113

    		Fluorescent Dye Others
    Acid blue 113 is an azo dye whose staining effect is effectively removed by nanoscale zero-valent iron (NZVI) particles.
    Acid blue 113
  • HY-15380
    PNU‐142721

    		HIV Reverse Transcriptase Infection
    PNU-142721 is a reverse transcriptase inhibitor and PXR agonist that effectively inhibits various type I HIV variants .
    PNU‐142721
  • HY-177782
    SB1349

    		Molecular Glues MicroRNA Cancer
    SB1349 is a molecular glucose degrading agent that targets the Lin28 protein. SB1349 can effectively induce proteasome dependent degradation of Lin28A and Lin28B. SB1349 can increase the level of mature let-7 miRNA, downregulate the oncogenes targeted by let-7, and effectively induce the differentiation of neuroblastoma cells. SB1349 can be used for cancer research .
    SB1349
  • HY-B0560A
    Ammonium aluminum sulfate dodecahydrate

    		Biochemical Assay Reagents
    Ammonium aluminum sulfate dodecahydrate is a biomolecule precipitation agent that can change the solubility of proteins by interacting with water molecules, thereby effectively purifying proteins.
    Ammonium aluminum sulfate dodecahydrate
  • HY-149606
    TKB245

    		SARS-CoV Infection
    TKB245 is a highly potent SARS-CoV-2 Mpro inhibitor that effectively blocks SARS-CoV-2 replication in VeroE6 cells .
    TKB245
  • HY-N7314
    Asebogenin

    		Syk Inflammation/Immunology
    Asebogenin has antimalarial activity in vitro . Asebogenin can inhibit the phosphorylation of Syk, thereby effectively suppressing platelet activation and the formation of neutrophil extracellular traps .
    Asebogenin
  • HY-129577
    Aplysin

    		Necroptosis Inflammation/Immunology Cancer
    Aplysin is a brominated sesquiterpene with an isoprene backbone that exhibits hepatoprotective, immunomodulatory, and antitumor activities. Aplysin effectively prevents spontaneous pancreatic necrosis and inflammatory responses in NOD mice .
    Aplysin
  • HY-135381
    3-Oxo Atorvastatin

    		Drug Metabolite Cardiovascular Disease
    3-Oxo Atorvastatin is an impurity of 3-Oxo Atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor and has the ability to effectively decrease blood lipids .
    3-Oxo Atorvastatin
  • HY-165370
    BMS-791826

    		Glucocorticoid Receptor AP-1 NF-κB Inflammation/Immunology
    BMS-791826 is a selective glucocorticoid receptor modulator. BMS-791826 effectively binds to glucocorticoid receptors and effectively inhibits AP-1 and NF-κB-dependent reporter. BMS-791826 can be used in the research of inflammatory diseases .
    BMS-791826
  • HY-W838042
    Hedgehog IN-8

    		Hedgehog Phosphodiesterase (PDE) Others
    Hedgehog IN-8 effectively inhibits hedgehog signaling and phosphodiesterase activity.
    Hedgehog IN-8
  • HY-W779377
    Erythromycin B

    		Parasite Infection
    Erythromycin B has anti-malarial activity and effectively inhibits the asexual reproduction of Plasmodium falciparum .
    Erythromycin B
  • HY-19601
    Carzelesin

    U 80244

    		 Drug Intermediate Cancer
    Carzelesin is a cyclopropylpyrroloindole precursor molecule and effectively inhibits tumor growth. Carzelesin may be used in cancer research.
    Carzelesin
  • HY-170936
    MY-1576

    		FAK Hippo (MST) YAP Cancer
    MY-1576 is a FAK inhibitor with an IC50 of 8 nM. MY-1576 can activate the Hippo pathway, thereby blocking the regulation of YAP/TAZ. MY-1576 also effectively inhibits tumor growth in the KYSE30 xenograft mouse model, demonstrating good safety, and effectively downregulates the autophosphorylation of FAK and the levels of YAP/TAZ in vivo .
    MY-1576

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: