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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
32 Results for "
infantile diarrhoea
" in MedChemExpress (MCE) Product Catalog:
Products (32)
32 Results for "infantile diarrhoea" in MCE Product Catalog:
88
88 Publications Verification
Synonyms: Dimethyloxallyl Glycine
Target:
Research Areas:
DMOG (Dimethyloxallyl Glycine) is a cell permeable and competitive inhibitor of HIF-PH, which results in HIF-1α stabilisation and accmulation in vitro and in vivo . DMOG is an α-ketoglutarate analogue and inhibits α-KG-dependent hydroxylases. DMOG acts as a pro-angiogenic agent and plays a protective role in experimental model of colitis and diarrhoea via HIF-1 related signal . DMOG induces cell autophagy .
13
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Loperamide (ADL 2-1294) is selective and orally active μ opioid receptor agonist with Ki valuess of 3, 48 and 1156 nM against μ, δ and κ opioid receptor, respectively. Loperamide produces antinociception and antihyperalgesia. Loperamide exhibits peripheral selectivity, enhancing fluid, electrolyte, and glucose absorption, reversing PGE2 (HY-101952)- and Cholera toxin (HY-P1446)-induced intestinal secretion, and reducing intestinal motility. Loperamide can be used for the researches of inflammatory pain and protracted diarrhoea .
6
6 Cited Publications
Cat. No.: HY-17494
CAS No.: 26839-75-8
Synonyms: (S)-L-714,465; MK 950 free base
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Research Areas:
Timolol is a β-blocker available for both topical and systemic administration. Topical Timolol is primarily used to reduce intraocular pressure with open-angle glaucoma and ocular hypertension. Timolol can also be used for the research of infantile hemangiomas, hypertension, myocardial infarction, migraine prophylaxis, and atrial fibrillation.Timolol also has cardioprotective effect .
2
2 Cited Publications
Cat. No.: HY-16134A
CAS No.: 141117-12-6
Synonyms: MBI 3253 hydrochloride; MDL 28574 hydrochloride; MX3253 hydrochloride
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Research Areas:
Celgosivir hydrochloride (MBI 3253 hydrochloride; MDL 28574 hydrochloride; MX3253 hydrochloride) is an α-glucosidase I inhibitor; inhibits bovine viral diarrhoea virus (BVDV) with an IC50 of 1.27 μM in in vitro assay.
2
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Research Areas:
Celgosivir (MBI 3253; MDL 28574; MX3253) is an α-glucosidase I inhibitor; inhibits bovine viral diarrhoea virus (BVDV) with an IC50 of 1.27 μM in in vitro assay.
1
1 Cited Publications
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DB772 hydrate is a bovine viral diarrhoea virus (BVDV) inhibitor. DB772 also has anti-prion activity .
1
1 Cited Publications
Cat. No.: HY-114621A
Purity: 99.89%
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Research Areas:
DB772 hydrate is a bovine viral diarrhoea virus (BVDV) inhibitor. DB772 also has anti-prion activity .
1
1 Cited Publications
Cat. No.: HY-P71230
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PPT1; INCL; Prev. PPT; Ceroid-Lipofuscinosis, Neuronal 1, infantile; CLN1; PPT-1; Palmitoyl-Protein Hydrolase 1; Palmitoyl-Protein Thioesterase 1; Ceroid-Palmitoyl-Palmitoyl-Protein Thioesterase 1
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P700622
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PPT1; INCL; Prev. PPT; Ceroid-Lipofuscinosis, Neuronal 1, infantile; CLN1; PPT-1; Palmitoyl-Protein Hydrolase 1; Palmitoyl-Protein Thioesterase 1; Ceroid-Palmitoyl-Palmitoyl-Protein Thioesterase 1
Species:
Mouse
Source:
HEK293
Synonyms: ENB-0040
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Research Areas:
Target:
Category:
Microorganisms Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields
Target:
Category:
Plants Infection Flavonoids Deguelia rufescens (Benth.) R.A.Camargo & A.M.G.Azevedo Flavonones Phenols Polyphenols Compositae Extract Disease Research Fields Inflammation/Immunology
Target:
Cat. No.: HY-164838
CAS No.: 1831135-57-9
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ABC47 is a potent inhibitor of serine hydrolases. ABC47 shows IC50s of 0.03 and 0.1 μM for ABHD4 and ABHD3, respectively. ABC47 plays an important role in infantile neuronal ceroid lipofuscinosis research .
Cat. No.: HY-P3498
CAS No.: 914009-84-0
Synonyms: ZP1846
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Research Areas:
ABC44 is a potent serine hydrolase inhibitor with IC50s of 0.1 μM and 6.5 μM for palmitoyl protein thioesterase 1 (PPT1) in situ and in vitro, respectively. ABC44 can be used for researching infantile neuronal ceroid lipofuscinosis .
Cat. No.: HY-15893R
CAS No.: 89464-63-1
Synonyms: Dimethyloxallyl Glycine (Standard)
Research Areas:
DMOG (Standard) is the analytical standard of DMOG. This product is intended for research and analytical applications. DMOG (Dimethyloxallyl Glycine) is a cell permeable and competitive inhibitor of HIF-PH, which results in HIF-1α stabilisation and accmulation in vitro and in vivo . DMOG is an α-ketoglutarate analogue and inhibits α-KG-dependent hydroxylases. DMOG acts as a pro-angiogenic agent and plays a protective role in experimental model of colitis and diarrhoea via HIF-1 related signal . DMOG induces cell autophagy .
Cat. No.: HY-116910
CAS No.: 640897-20-7
Target:
Research Areas:
CPP-115 is a GABA transaminase inactivator with higher affinity and lower retinal toxicity than Vigabatrin (HY-15399). CPP-115 increases brain GABA levels by inhibiting GABA transaminase catabolism. CPP-115 can be used in the study of drug addiction and infantile spasms .
Cat. No.: HY-19876
CAS No.: 935481-06-4
Synonyms: Debio-0827
Research Areas:
PL37 (Debio-0827) is an orally active, blood-brain barrier permeable dual enkephalinase inhibitor. PL37 inhibits aminopeptidase N, neprilysin, and metalloproteases, thereby blocking the degradation of endogenous enkephalins, elevating enkephalin levels, and activating peripheral μ- and δ-opioid receptors. PL37 induces mitochondrial dysfunction, mitophagy, and apoptosis, inhibits endothelial cell proliferation, migration, invasion, and tube formation, and suppresses hemangioma tumor growth and angiogenesis. PL37 can be used in research related to peripheral neuropathic pain, osteosarcoma-induced hyperalgesia, painful diabetic neuropathy, migraine, bone cancer pain, neuroinflammatory pain, and infantile hemangioma .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
