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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
25 Results for "
leprosy
" in MedChemExpress (MCE) Product Catalog:
Products (25)
25 Results for "leprosy" in MCE Product Catalog:
13
13
13 Publications Verification
Synonyms: BL-191; PTX; Oxpentifylline
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Target:
4
4 Cited Publications
Synonyms: 4,4′-Diaminodiphenyl sulfone; DDS
Research Areas:
Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities . Dapsone?exerts effective antileprosy activity?and inhibits folate synthesis in cell extracts of?M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al .
2
2 Cited Publications
Cat. No.: HY-B0306
CAS No.: 14222-60-7
Synonyms: Protionamide
Prothionamide is an orally active thioamide antibacterial agent. Prothionamide is a substrate of OCT1 with a Km value of 805.8 μM. Prothionamide reacts with NAD to form a covalent adduct, with the adduct being a tight-binding inhibitor of Mycobacterium tuberculosis and Mycobacterium leprae InhA. Prothionamide can effectively inhibit the growth of Mycobacterium tuberculosis (MIC = ~0.5 µg/mL) and Mycobacterium leprae. Prothionamide is used in the research of tuberculosis and leprosy .
Cat. No.: HY-162836
CAS No.: 13929-35-6
Synonyms: 4-O-(Carboxymethyl)-Rifamycin
Target:
Research Areas:
Rifamycin B (4-O-(Carboxymethyl)-Rifamycin) is a member of ansamycin antibiotics family with an anti-mycobacterial activity against tuberculosis, leprosy and AIDS-related mycobacterial infections. Rifamycin B is a metabolic product of Nocardia inediterranei, which can yield Rifamycin O and Rifamycin S (HY-125365) by microbial transformation .
Cat. No.: HY-B0688S2
CAS No.: 1632119-29-9
Synonyms: 4,4′-Diaminodiphenyl sulfone-13C12; DDS-13C12
Cat. No.: HY-W654329
CAS No.: 2468639-68-9
Cat. No.: HY-B0688S1
CAS No.: 1346602-12-7
Synonyms: 4,4′-Diaminodiphenyl sulfone-d4; DDS-d4
Synonyms: BL-191 (Standard); PTX (Standard); Oxpentifylline (Standard)
Research Areas:
Pentoxifylline (Standard) is the analytical standard of Pentoxifylline. This product is intended for research and analytical applications. Pentoxifylline (BL-191), a haemorheological agent, is an orally active non-selective phosphodiesterase (PDE) inhibitor, with immune modulation, anti-inflammatory, hemorheological, anti-fibrinolytic and anti-proliferation effects. Pentoxifylline can be used for the research of peripheral vascular disease, cerebrovascular disease and a number of other conditions involving a defective regional microcirculation .
Synonyms: 4,4′-Diaminodiphenyl sulfone (Standard); DDS (Standard)
Research Areas:
Dapsone (Standard) is the analytical standard of Dapsone. This product is intended for research and analytical applications. Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities . Dapsone exerts effective antileprosy activity and inhibits folate synthesis in cell extracts of M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al .
Cat. No.: HY-125365R
CAS No.: 13553-79-2
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Research Areas:
Acedapsone is a compound with antimalarial and antimicrobial activities. Acedapsone is mainly used as a long-acting leprosy inhibitor .
Cat. No.: HY-W699159
CAS No.: 557794-37-3
Cat. No.: HY-B0688S3
CAS No.: 287476-19-1
Synonyms: 4,4′-Diaminodiphenyl sulfone-15N2; DDS-15N2
Cat. No.: HY-B0306S
CAS No.: 1330261-26-1
Synonyms: Protionamide-d5
Cat. No.: HY-B0306R
CAS No.: 14222-60-7
Synonyms: Protionamide (Standard)
Target:
Research Areas:
Prothionamide (Standard) is the analytical standard of Prothionamide (HY-B0306). This product is intended for research and analytical applications. Prothionamide is an orally active thioamide antibacterial agent. Prothionamide is a substrate of OCT1 with a Km value of 805.8 μM. Prothionamide reacts with NAD to form a covalent adduct, with the adduct being a tight-binding inhibitor of Mycobacterium tuberculosis and Mycobacterium leprae InhA. Prothionamide can effectively inhibit the growth of Mycobacterium tuberculosis (MIC = ~0.5 µg/mL) and Mycobacterium leprae. Prothionamide is used in the research of tuberculosis and leprosy .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
