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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
54 Results for "
natural killer cell cytotoxicity
" in MedChemExpress (MCE) Product Catalog:
Products (54)
54 Results for "natural killer cell cytotoxicity" in MCE Product Catalog:
3
1
Target:
Research Areas:
Urelumab, a fully human, non-ligand binding, CD137 agonist IgG4 monoclonal antibody, enhances T-cell and natural killer-cell antitumor activity, and may enhance cytotoxic activity of Rituximab (HY-P9913). Urelumab can be used for the research of diffuse large B-cell lymphoma (DLBCL), follicular lymphoma (FL), and other types of non-Hodgkin lymphoma (NHL) .
1
1 Cited Publications
Synonyms: Cycloartenol ferulate; Cycloartenol ferulic acid ester
Cat. No.: HY-P9965
CAS No.: 915296-00-3
Synonyms: HuLuc 63; PDL 063; BMS 901608
Target:
Research Areas:
Cat. No.: HY-160421
CAS No.: 2000236-36-0
Target:
Research Areas:
TREM2-IN-1 (OPA) is a TREM2 inhibitor derived from oxaliplatin and artesunate. TREM2-IN-1 can relieves immunosuppressive tumor microenvironment and enhancing chemical anticancer efficiency. TREM2-IN-1 deters the tumor growth in mice models bearing MC38 colorectal tumor by reducing the number of CD206 + and CX3CR1 + immunosuppressive macrophages. TREM2-IN-1 also promotes the expansion and infiltration of immunostimulatory dendritic, cytotoxic T and natural killer cells .
Cat. No.: HY-Y0493
CAS No.: 28230-32-2
Synonyms: HOOBt
HODHBt (HOOBt) inhibits STAT5-SUMO interaction by blocking SUMOylation of phosphorylated STAT5. HODHBt enhances the magnitude of IL-15 signaling and significantly increases the natural killer (NK) cell cytotoxicity phenotype and function and the generation of cytokine-induced memory-like (CIML) natural killer (NK) cells. HODHBt can be used for research of HIV-infection and cancer .
Cat. No.: HY-172240
CAS No.: 1418305-55-1
Synonyms: TU2218 free base
Research Areas:
Tosposertib (TU2218 free base) is an ALK5/VEGFR2 dual inhibitor (IC50 = 1.2 nM/4.9 nM). Tosposertib directly restores the activity of damaged cytotoxic T lymphocytes (CTLs) and natural killer cells inhibited by TGFβ and suppresses the activity and viability of regulatory T cells. Tosposertib can be used for the study of melanoma and colon cancer .
Cat. No.: HY-P9977A
Cat. No.: HY-P99759
CAS No.: 1622189-43-8
Synonyms: IL-15N72D
Target:
Research Areas:
Cat. No.: HY-P990178
Research Areas:
Infection Others Metabolic Disease Inflammation/Immunology Cancer
Anti-Mouse NKG2D/CD314 Antibody (CX5) is a rat-derived IgG1 κ type antibody inhibitor, targeting to mouse NKG2D/CD314. Anti-Mouse NKG2D/CD314 Antibody (CX5) reduces cytotoxicity of natural killer cells. Anti-Mouse NKG2D/CD314 Antibody (CX5) can be used for the researches of cancer, infection, inflammation, immunology and metabolic disease, such as colitis and diabetes .
Cat. No.: HY-P10563
CAS No.: 2580150-96-3
Synonyms: BHV-1100
Cat. No.: HY-174736
Target:
Research Areas:
Human CD70 mRNA encodes the human CD70 molecule (CD70) protein, a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. CD70 induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. It is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.
Cat. No.: HY-P991136
CAS No.: 3009874-10-3
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Cat. No.: HY-175604
CAS No.: 1061105-16-5
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SCL-1 is an orally active anti-PD-1/PD-L1 inhibitor. SCL-1 can inhibit PD-1/PD-L1 binding. SCL-1 increases T cells, B cells and natural killer cells. SCL-1 exerts strong tumor growth inhibitory effects that were mediated by effector T-cell induction inside tumors and the up-regulated expression of long non-coding RNAs as neoantigens leading to cytotoxic T lymphocyte activation. SCL-1 can be used for the research of cancer, such as triple-negative breast cancer .
Cat. No.: HY-P990719
CAS No.: 2736449-62-8
Synonyms: XmAb24306
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Cat. No.: HY-P11340
CAS No.: 202657-61-2
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Cat. No.: HY-174622
Target:
Research Areas:
Human IL21 mRNA encodes the human interleukin 21 (IL21) protein, a member of the common-gamma chain family of cytokines. IL21 plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells.
Cat. No.: HY-P991250
Cat. No.: HY-P72506
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NCR3; Activating natural killer Receptor P30; Prev. LY117; NK-P30; NKp30; Activating NK-A1 Receptor; 1C7; CD337 Antigen; natural killer cell P30-Related Protein; MALS; CD337; natural cytotoxicity Triggering Receptor 3; Lymphocyte Antigen 117
Species:
Human
Source:
HEK293
Cat. No.: HY-P77106
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NCR3; Activating natural killer Receptor P30; Prev. LY117; NK-P30; NKp30; Activating NK-A1 Receptor; 1C7; CD337 Antigen; natural killer cell P30-Related Protein; MALS; CD337; natural cytotoxicity Triggering Receptor 3; Lymphocyte Antigen 117
Species:
Rat
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
