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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
31 Results for "
parasitic diseases
" in MedChemExpress (MCE) Product Catalog:
Products (31)
31 Results for "parasitic diseases" in MCE Product Catalog:
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Target:
Research Areas:
Diclazuril (R-64433), a benzeneacetonitrile derivative, is a potent and orally active anticoccidial agent. Diclazuril can be used for the research of certain infectious and parasitic diseases, including coccidiosis, acute toxoplasmosis, equine protozoal pyoencephalitis (EPM) et.al .
Cat. No.: HY-B0357S
CAS No.: 1632495-80-7
Synonyms: R-64433-d4
Dehydroemetine is an orally active antiparasitic agent. Dehydroemetine can inhibit parasites such as Entamoeba histolytica, and it can also be used in the research of parasitic diseases like visceral leishmaniasis .
Cat. No.: HY-W020785
CAS No.: 98886-44-3
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Research Areas:
Fosthiazate is an inhibitor of acetylcholinesterase (Acetylcholinesterase, AChE). Fosthiazate exhibits significant nematicidal activity and systemic insecticidal activity. Fosthiazate is applicable to studies on plant-parasitic nematodes, root-knot diseases, agricultural pests, as well as the ecotoxicology and environmental behavior of organophosphorus compounds .
Synonyms: 5β-Hydroxyecdysterone
Polypodine B is a natural ecdysone ester isolated from the bark of Dacrydium intermedium. Polypodine B significantly inhibits the activity of Acanthamoeba castellani. Polypodine B has moderate antifungal activity. Polypodine B can be used for research on parasitic diseases and fungal infections .
Cat. No.: HY-N15748
CAS No.: 287974-44-1
Synonyms: (-)-Pelorol
Target:
Cat. No.: HY-W342283
CAS No.: 536-71-0
Target:
Parasite Angiotensin-converting Enzyme (ACE) Angiotensin Receptor p38 MAPK STAT NF-κB TNF Receptor 5-HT Receptor
Research Areas:
Diminazene is an antiparasitic agent widely used to treat parasitic diseases caused by hemoparasites (such as trypanosomes and babesia). Diminazene acts as an ACE2 activator and exerts cardiovascular protective effects by activating the ACE2/Ang-(1-7)/Mas receptor axis. By regulating gut microbiota-tryptophan metabolism, Diminazene inhibits the activation of core inflammatory signaling pathways including MAPK, STAT and NF-κB, increases central 5-HT levels, and suppresses splenic TNF-α production, thereby alleviating systemic inflammation .
Cat. No.: HY-118338
CAS No.: 1076088-50-0
WRR-483 is an analog of K11777, an inhibitor of cruzain, used to inhibit the proliferation of Trypanosoma cruzi in cell culture. WRR-483 can eradicate parasitic infection in an acute Chagas disease mouse model. WRR-483 is an irreversible cysteine protease inhibitor that shows pH-dependent high affinity and potent trypanocidal activity against cruzain and T. cruzi infection, and is expected to inhibit Chagas disease.
Cat. No.: HY-137007
CAS No.: 1496553-39-9
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Research Areas:
SMA-12b is a small molecule analogue of the parasitic worm compound ES-62. SMA-12b has immunomodulatory activity, acting by regulating the expression of multiple inflammatory response genes, especially those associated with inflammatory bodies. SMA-12b significantly reduces the expression of cytokine IL-1β associated with inflammatory bodies and inhibites the production of IL-1β through a mechanism mediated by NRF2. SMA-12b can be used in the study of rheumatoid arthritis (RA) and other autoimmune diseases .
Cat. No.: HY-W268334
CAS No.: 17952-82-8
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1,2,3,4-Tetrahydronorharman-1-one is a manzamine alkaloid with activity against infectious and tropical parasitic diseases from an Indonesian sponge .
Cat. No.: HY-B0357A
CAS No.: 112209-98-0
Synonyms: R-64433 potassium
Target:
Research Areas:
Diclazuril (R-64433) potassium, a benzeneacetonitrile derivative, is a potent and orally active anticoccidial agent. Diclazuril potassium can be used for the research of certain infectious and parasitic diseases, including coccidiosis, acute toxoplasmosis, equine protozoal pyoencephalitis (EPM) et.al .
Cat. No.: HY-175305
CAS No.: 3052352-22-1
DMU759 is a Lysyl-tRNA synthetase 1 (KRS1) inhibitor. DMU759 has potent anti-kinetoplastid activity against Trypanosoma cruzi , Trypanosoma brucei and Leishmania donovani. DMU759 significantly reduces parasitemia in acute Chagas disease mice model. DMU759 can be used for parasitic infection like Chagas disease research .
Cat. No.: HY-N1944S
Cat. No.: HY-B0357R
CAS No.: 101831-37-2
Synonyms: R-64433 (Standard)
Target:
Research Areas:
Diclazuril (Standard) is the analytical standard of Diclazuril. This product is intended for research and analytical applications. Diclazuril (R-64433), a benzeneacetonitrile derivative, is a potent and orally active anticoccidial agent. Diclazuril can be used for the research of certain infectious and parasitic diseases, including coccidiosis, acute toxoplasmosis, equine protozoal pyoencephalitis (EPM) et.al .
Cat. No.: HY-W654156
Cat. No.: HY-W020785R
CAS No.: 98886-44-3
Research Areas:
Fosthiazate (Standard) is the analytical standard of Fosthiazate (HY-W020785). This product is intended for research and analytical applications. Fosthiazate is an inhibitor of acetylcholinesterase (Acetylcholinesterase, AChE). Fosthiazate exhibits significant nematicidal activity and systemic insecticidal activity. Fosthiazate is applicable to studies on plant-parasitic nematodes, root-knot diseases, agricultural pests, as well as the ecotoxicology and environmental behavior of organophosphorus compounds .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
