10169 Results for "

product

" in MedChemExpress (MCE) Product Catalog:
Products (10169)

10169 Results for "product" in MCE Product Catalog:

296
Trametinib (DMSO solvate)
Trametinib (DMSO solvate)
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296 Publications Verification
Cat. No.: HY-10999A
CAS No.: 1187431-43-1
Purity:  99.56%
Synonyms: GSK-1120212 (DMSO solvate); JTP-74057 (DMSO solvate)
Target:  

MEK Apoptosis

Research Areas:  

Cancer

Trametinib (DMSO solvate) (GSK-1120212 (DMSO solvate)) is an orally active MEK inhibitor that inhibits MEK1 and MEK2 with IC50s of about 2 nM. Trametinib (DMSO solvate) activates autophagy and induces apoptosis . This product is in solid form, a DMSO solvate, and a stable crystalline form.
88
Genistein (Standard)
Genistein (Standard)
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88 Cited Publications
Cat. No.: HY-14596R
CAS No.: 446-72-0
Purity:  99.31%
Synonyms: NPI 031L (Standard)
Category:  

Anti-aging Plants Endogenous metabolite Human Gut Microbiota Metabolites Flavonoids Leguminosae Glycine max (L.) merr Sunscreen Phenols Cosmetic Research Disease Research Fields Glycyrrhiza uralensis Fisch. Cancer

Target:  

Reference Standards EGFR Autophagy Apoptosis Endogenous Metabolite

Genistein (Standard) is the analytical standard of Genistein. This product is intended for research and analytical applications. Genistein, a soy isoflavone, is a multiple tyrosine kinases (e.g., EGFR) inhibitor which acts as a chemotherapeutic agent against different types of cancer, mainly by altering apoptosis, the cell cycle, and angiogenesis and inhibiting metastasis.
86
Hydrocortisone (Standard)
Hydrocortisone (Standard)
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86 Cited Publications
Cat. No.: HY-N0583R
CAS No.: 50-23-7
Synonyms: Cortisol (Standard)
Category:  

Endogenous metabolite Disease Research Fields Endocrinology Cancer Steroids

Target:  

Reference Standards Glucocorticoid Receptor Endogenous Metabolite

Hydrocortisone (Standard) is the analytical standard of Hydrocortisone. This product is intended for research and analytical applications. Hydrocortisone (Cortisol) is a steroid hormone or glucocorticoid secreted by the adrenal cortex .
85
Cholesterol (Water Soluble)
Cholesterol (Water Soluble)
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85 Cited Publications
Cat. No.: HY-N0322A
Category:  

Other Diseases Endogenous metabolite Disease Research Fields Steroids

Target:  

Liposome

Cholesterol Water Soluble is a major sterol in mammals, constituting 20-25% of the structural composition of the plasma membrane. The plasma membrane is highly permeable to water but relatively impermeable to ions and protons. Cholesterol Water Soluble plays an important role in determining the fluidity and permeability characteristics of membranes and the function of transporters and signaling proteins. Cholesterol Water Soluble is also an endogenous estrogen-related receptor alpha (ERRα) agonist. Cholesterol Water Soluble can be used to study the effects of cholesterol on potassium currents in inner hair cells .
(Note: This product is a mixture of Cholesterol and Methyl-β-cyclodextrin. The product specifications below only indicate the effective content of Cholesterol.)
83
Simvastatin (Standard)
Simvastatin (Standard)
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83 Cited Publications
Cat. No.: HY-17502R
CAS No.: 79902-63-9
Synonyms: MK 733 (Standard)
Target:  

Reference Standards HMG-CoA Reductase (HMGCR) Autophagy Mitophagy Apoptosis Ferroptosis

Research Areas:  

Cardiovascular Disease Cancer

Simvastatin (Standard) is the analytical standard of Simvastatin. This product is intended for research and analytical applications. Simvastatin (MK 733) is a competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM.
72
Mifepristone (Standard)
Mifepristone (Standard)
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72 Cited Publications
Cat. No.: HY-13683R
CAS No.: 84371-65-3
Purity:  98.49%
Synonyms: RU486 (Standard); RU 38486 (Standard)
Target:  

Reference Standards Progesterone Receptor Glucocorticoid Receptor NO Synthase Autophagy

Research Areas:  

Endocrinology Cancer

Mifepristone (Standard) is the analytical standard of Mifepristone. This product is intended for research and analytical applications. Mifepristone (RU486) is a progesterone receptor (PR) and glucocorticoid receptor (GR) antagonist with IC50s of 0.2 nM and 2.6 nM in in vitro assay .
64
Trastuzumab
Trastuzumab
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64 Cited Publications
Cat. No.: HY-P9907
CAS No.: 180288-69-1
Synonyms: Anti-Human HER2, Humanized Antibody

Target:  

Radionuclide-Drug Conjugates (RDCs) EGFR ADC Antibodies

Research Areas:  

Cancer

Trastuzumab is a humanized IgG1 monoclonal antibody that selectively binds to HER2 with high affinity. Trastuzumab can be used for the research of HER2-positive metastatic breast cancer and gastric cancer . (Note: The product specifications below only indicate the effective content of Trastuzumab. The component ratio of this product is Trastuzumab : excipients = 1:0.6-1:0.9.)
56
Prostaglandin E2 (Standard)
Prostaglandin E2 (Standard)
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56 Cited Publications
Cat. No.: HY-101952R
CAS No.: 363-24-6
Synonyms: PGE2(Standard); Dinoprostone (Standard)
Category:  

Ketones, Aldehydes, Acids Disease markers Nervous System Disorder Endogenous metabolite Disease Research Fields Endocrinology

Target:  

Reference Standards Prostaglandin Receptor Endogenous Metabolite

Prostaglandin E2 (Standard) is the analytical standard of Prostaglandin E2. This product is intended for research and analytical applications. Prostaglandin E2 (PGE2) is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammation.
54
Arachidonic acid (Standard)
Arachidonic acid (Standard)
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54 Cited Publications
Cat. No.: HY-109590R
CAS No.: 506-32-1
Synonyms: Immunocytophyt (Standard)
Target:  

Reference Standards Endogenous Metabolite

Research Areas:  

Cardiovascular Disease Inflammation/Immunology

Arachidonic acid (Immunocytophyt) (Standard) is the analytical standard of Arachidonic acid (HY-109590). This product is intended for research and analytical applications. Arachidonic acid is an essential fatty acid and a major constituent of biomembranes.
51
Lactic acid sodium (60% w/w in water)
Lactic acid sodium (60% w/w in water)
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51 Cited Publications
Cat. No.: HY-B2227B
CAS No.: 72-17-3
Synonyms: DL-Lactic acid sodium; E-270 sodium
Target:  

Environmental Pollutants Endogenous Metabolite Bacterial Hydroxycarboxylic Acid Receptor (HCAR)

Research Areas:  

Infection Metabolic Disease Inflammation/Immunology Cancer

Lactic acid (DL-Lactic acid) sodium (60% w/w in water) is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Lactic acid sodium (60% w/w in water) is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Lactic acid sodium (60% w/w in water) is an oncometabolite and has immune protective role of lactate in anti-tumor immunity . Lactic acid sodium (60% w/w in water) also has antimicrobial activity, which can be used as a food preservative .
This product has a content (w/w) of 60%, and 1 mL of the system contains 798 mg of Lactic acid sodium, i.e., a concentration of 798 mg/mL (i.e., 7.12 M).
47
Apigenin (Standard)
Apigenin (Standard)
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47 Cited Publications
Cat. No.: HY-N1201R
CAS No.: 520-36-5
Synonyms: 4',5,7-Trihydroxyflavone(Standard); Apigenol(Standard); C.I. Natural Yellow 1 (Standard)
Category:  

Plants Endogenous metabolite Human Gut Microbiota Metabolites Flavonoids Sunscreen Phenols Cosmetic Research Umbelliferae Disease Research Fields Baccharis sarothroides A.Gray Cancer

Target:  

Reference Standards Autophagy Cytochrome P450 Endogenous Metabolite

Apigenin (Standard) is the analytical standard of Apigenin. This product is intended for research and analytical applications. Apigenin (4',5,7-Trihydroxyflavone) is a competitive CYP2C9 inhibitor with a Ki of 2 μM.
45
Salidroside (Standard)
Salidroside (Standard)
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45 Cited Publications
Cat. No.: HY-N0109R
CAS No.: 10338-51-9
Synonyms: Rhodioloside (Standard)
Category:  

Rhodiola rosea Linn. Crassulaceae Phenols Plants Disease Research Fields Cancer

Target:  

Prolyl Endopeptidase (PREP) mTOR Apoptosis PINK1/Parkin Reference Standards

Salidroside (Standard) is the analytical standard of Salidroside. This product is intended for research and analytical applications. Salidroside (Rhodioloside) is a prolyl endopeptidase inhibitor. Salidroside alleviates cachexia symptoms in mouse models of cancer cachexia via activating mTOR signalling. Salidroside protects dopaminergic neurons by enhancing PINK1/Parkin-mediated mitophagy.
44
Probenecid (Standard)
Probenecid (Standard)
0 Images
44 Cited Publications
Cat. No.: HY-B0545R
CAS No.: 57-66-9
Target:  

Reference Standards TRP Channel Bacterial HIV

Research Areas:  

Metabolic Disease Cancer

Probenecid (Standard) is the analytical standard of Probenecid. This product is intended for research and analytical applications. Probenecid is a potent and selective agonist of transient receptor potential vanilloid 2 (TRPV2) channels. Probenecid also inhibits pannexin 1 channels.
35
Lovastatin (Standard)
Lovastatin (Standard)
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35 Cited Publications
Cat. No.: HY-N0504R
CAS No.: 75330-75-5
Synonyms: Mevinolin (Standard)
Category:  

Microorganisms Ketones, Aldehydes, Acids Disease Research Fields Cancer

Target:  

Reference Standards HMG-CoA Reductase (HMGCR) Autophagy Ferroptosis

Lovastatin (Standard) is the analytical standard of Lovastatin. This product is intended for research and analytical applications. Lovastatin is a cell-permeable HMG-CoA reductase inhibitor used to lower cholesterol.
35
Medroxyprogesterone acetate (Standard)
Medroxyprogesterone acetate (Standard)
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35 Cited Publications
Cat. No.: HY-B0469R
CAS No.: 71-58-9
Synonyms: Medroxyprogesterone 17-acetate(Standard); Farlutin (Standard)
Category:  

Endogenous metabolite Disease Research Fields Cancer Steroids

Target:  

Reference Standards Progesterone Receptor Androgen Receptor Glucocorticoid Receptor Endogenous Metabolite

Medroxyprogesterone acetate (Standard) is the analytical standard of Medroxyprogesterone acetate. This product is intended for research and analytical applications. Medroxyprogesterone acetate is a widely used synthetic steroid by its interaction with progesterone, androgen and glucocorticoid receptors .
34
Progesterone (Standard)
Progesterone (Standard)
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34 Cited Publications
Cat. No.: HY-N0437R
CAS No.: 57-83-0
Synonyms: Pregn-4-ene-3,20-dione (Standard)
Category:  

Other disease Disease markers Endogenous metabolite Disease Research Fields Cancer Steroids

Target:  

Reference Standards Progesterone Receptor Endogenous Metabolite

Progesterone (Standard) is the analytical standard of Progesterone. This product is intended for research and analytical applications. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.
33
Fisetin (Standard)
Fisetin (Standard)
0 Images
33 Cited Publications
Cat. No.: HY-N0182R
CAS No.: 528-48-3
Category:  

Neurological Disease Anti-aging Rosaceae Metabolic Disease Plants Flavonoids Phenols Disease Research Fields Inflammation/Immunology Cancer Fragaria × ananassa Duch.

Target:  

Reference Standards Sirtuin PPAR TNF Receptor

Fisetin (Standard) is the analytical standard of Fisetin. This product is intended for research and analytical applications. Fisetin is a natural flavonol found in many fruits and vegetables with various benefits, such as antioxidant, anticancer, neuroprotection effects.
33
Liothyronine (Standard)
Liothyronine (Standard)
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33 Cited Publications
Cat. No.: HY-A0070AR
CAS No.: 6893-02-3
Synonyms: Triiodothyronine (Standard); 3,3',5-Triiodo-L-thyronine (Standard); T3 (Standard)
Category:  

Microorganisms Monophenols Ketones, Aldehydes, Acids Disease markers Endocrine diseases Phenols Endogenous metabolite Disease Research Fields Endocrinology

Target:  

Thyroid Hormone Receptor Endogenous Metabolite Reference Standards

Liothyronine (Standard) is the analytical standard of Liothyronine. This product is intended for research and analytical applications. Liothyronine is an active form of thyroid hormone. Liothyronine is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively .
32
Orlistat (Standard)
Orlistat (Standard)
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32 Cited Publications
Cat. No.: HY-B0218R
CAS No.: 96829-58-2
Synonyms: Tetrahydrolipstatin (Standard); Ro-18-0647 (Standard)
Target:  

Reference Standards Fatty Acid Synthase (FASN) Apoptosis

Research Areas:  

Metabolic Disease Cancer

Orlistat (Standard) is the analytical standard of Orlistat. This product is intended for research and analytical applications. Orlistat (Tetrahydrolipstatin) is a well-known irreversible inhibitor of pancreatic and gastric lipases. Orlistat is also an inhibitor of fatty acid synthase (FASN), is used orally for long-term research of obesity . Anti-atherosclerotic effect .
29
Myricetin (Standard)
Myricetin (Standard)
0 Images
29 Cited Publications
Cat. No.: HY-15097R
CAS No.: 529-44-2
Synonyms: Cannabiscetin (Standard)
Category:  

Anti-aging Plants Endogenous metabolite Human Gut Microbiota Metabolites Flavonoids Sunscreen Myrica nagi Cosmetic Research Disease Research Fields Cancer Myricaceae

Target:  

Reference Standards Apoptosis Autophagy Endogenous Metabolite

Myricetin (Standard) is the analytical standard of Myricetin. This product is intended for research and analytical applications. Myricetin is a common plant-derived flavonoid with a wide range of activities including strong anti-oxidant, anticancer, antidiabetic and anti-inflammatory activities.
Assay Types