31 Results for "

rabies

" in MedChemExpress (MCE) Product Catalog:
Products (31)

31 Results for "rabies" in MCE Product Catalog:

26
26 Publications Verification
Cat. No.: HY-18980
CAS No.: 82-08-6
Synonyms: Mallotoxin; NSC 56346; NSC 94525
Rottlerin, a natural product purified from Mallotus Philippinensis, is a specific PKC inhibitor, with IC50 values for PKCδ of 3-6 μM, PKCα,β,γ of 30-42 μM, PKCε,η,ζ of 80-100 μM. Rottlerin acts as a direct mitochondrial uncoupler, and stimulates autophagy by targeting a signaling cascade upstream of mTORC1. Rottlerin induces apoptosis via caspase 3 activation . Rottlerin inhibits HIV-1 integration and Rabies virus (RABV) infection .
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1 Cited Publications
Cat. No.: HY-P5623
CAS No.: 115136-25-9
Synonyms: RVG29; RDP; rabies Virus Glycoprotein-29
RVG (RVG29) is a blood-brain barrier-permeable peptide derived from rabies virus glycoprotein, which binds to the α-7 subunit of neuronal nicotinic acetylcholine receptor (AchR). RVG efficiently delivers drugs to nerve cells and antigen-presenting cells in a targeted manner, and enhances the efficiency of antigen presentation and drug delivery .
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1 Cited Publications
Cat. No.: HY-P0285
Rabies Virus Glycoprotein is a 29-amino-acid cell penetrating peptide derived from a rabies virus glycoprotein that can cross the blood-brain barrier (BBB) and enter brain cells.
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1 Cited Publications
Cat. No.: HY-172705
Target:  

Liposome nAChR

Research Areas:  

Neurological Disease

DSPE-PEG2000-RVG29 is a PEG conjugate composed of DSPE and rabies virus glycoprotein 29 (RVG29). RVG29 specifically binds to nicotinic acetylcholine receptors (nAChR) at the blood-brain barrier (BBB), crosses the BBB, and mediates receptor-dependent transcytosis. DSPE-PEG2000-RVG29 can be used for brain-targeted drug delivery, surface modification of nanocarriers, as well as gene and nucleic acid delivery. DSPE-PEG2000-RVG29 is applicable to research related to hypoxic-ischemic brain injury, Parkinson's disease, and other conditions .
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1 Cited Publications
Cat. No.: HY-P99792
CAS No.: 2449086-91-1
Synonyms: NM57; rhRIG

Target:  

RABV

Research Areas:  

Infection

Ormutivimab (rhRIG) is a recombinant human monoclonal antibody, targeting rabies virus. Ormutivimab neutralizes a variety of rabies virus strains. Ormutivimab exhibits potent potency against rabies post-exposure prophylaxis (PEP) model .
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1 Cited Publications
Cat. No.: HY-P0285A
Target:  

RABV

Research Areas:  

Infection

Rabies Virus Glycoprotein (TFA) is a 29-amino-acid cell penetrating peptide derived from a rabies virus glycoprotein that can cross the blood-brain barrier (BBB) and enter brain cells .
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1 Cited Publications
Cat. No.: HY-P5623B
Synonyms: RVG29 TFA; RDP TFA; rabies Virus Glycoprotein-29 TFA
Target:  

Bacterial

Research Areas:  

Infection

RVG TFA is a peptide derived from Rabies Virus Glycoprotein that binds to the α-7 subunit of nicotinic acetylcholine receptors (AchR) of neuronal cells. RVG enhances delivery of Mycobacterium tuberculosis antigens to antigen-presenting cells .
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1 Cited Publications
Cat. No.: HY-133735A
CAS No.: 2803211-60-9
Purity:  99.41%
Target:  

RABV

Research Areas:  

Infection

GRP-60367 hydrochloride is a first-in-class small-molecule rabies virus (RABV) entry inhibitor with nanomolar potency against some RABV strains. GRP-60367 hydrochloride specifically targets the RABV G protein .
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1 Cited Publications
Cat. No.: HY-133735
CAS No.: 1309241-34-6
Target:  

RABV

Research Areas:  

Infection

GRP-60367 is a first-in-class small-molecule rabies virus (RABV) entry inhibitor with nanomolar potency against some RABV strains .
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Cat. No.: HY-P5623A
CAS No.: 1186105-01-0
Synonyms: RVG29-Cys; RDP-Cys; rabies Virus Glycoprotein-29-Cys
Target:  

RABV

Research Areas:  

Others

RVG-Cys (RVG29-Cys) is a peptide derived from rabies virus glycoprotein (RVG29) with Cys attached to facilitate subsequent conjugation. RVG-Cys enhances the specific targeted delivery of proteins in brain tissue and neurons .
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Cat. No.: HY-P4086
CAS No.: 1678417-57-6
Target:  

RABV nAChR

Research Areas:  

Neurological Disease Cancer

Chimeric Rabies Virus Glycoprotein Fragment (RVG-9R) is a cell-penetrating peptide that is synthesized by adding nona-arginine motif to the carboxy terminus of RVG (rabies virus glycoprotein). Chimeric Rabies Virus Glycoprotein Fragment (RVG-9R) binds to
nAChR
on neuronal cells to mediate receptor-mediated endocytosis and targeted siRNA delivery. Chimeric Rabies Virus Glycoprotein Fragment (RVG-9R) protects complexed siRNA from degradation, enhances transcellular siRNA delivery in neuronal cells, and promotes efficient, pecific gene silencing. Chimeric Rabies Virus Glycoprotein Fragment (RVG-9R) can be used for the researches of neurological disease and cancer .
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Cat. No.: HY-P5623A1
Synonyms: RVG29-Cys acetate; RDP-Cys acetate; rabies Virus Glycoprotein-29-Cys acetate
Target:  

RABV

Research Areas:  

Others

RVG-Cys (RVG29-Cys) acetate is a peptide derived from rabies virus glycoprotein (RVG29) with Cys attached to facilitate subsequent conjugation. RVG-Cys acetate enhances the specific targeted delivery of proteins in brain tissue and neurons .
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Cat. No.: HY-172706
Target:  

Liposome nAChR

Research Areas:  

Neurological Disease

DSPE-PEG5000-RVG29 is a PEG compound which composed of DSPE and a Rabies virus glycoprotein 29 (RVG29). RVG29 can bind specifically to the nicotinic acetylcholine receptor (nAChR) at the blood-brain barrier (BBB) and cross over the BBB .
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Cat. No.: HY-P99727
CAS No.: 2419087-89-9
Synonyms: CTB012

Target:  

RABV

Research Areas:  

Infection

Mazorelvimab (CTB012) is an anti-rabies humanized IgG1κ monoclonal antibody that binds to the non-overlapping epitopes on the rabies virus (RABV) glycoprotein. Mazorelvimab binds to highly discontinuous conserved residues that are not in or near antigenic site III. Mezagitamab has potential application in the prevention of rabies .
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Cat. No.: HY-P99811
CAS No.: 944548-37-2
Synonyms: CR57

Target:  

RABV

Research Areas:  

Infection

Rafivirumab (CR57) is an anti-rabies virus monoclonal antibody for the prophylaxis of rabies. Rafivirumab has neutralizing potency against a broad spectrum of RABV variants. Rafivirumab can be used for research of cocktails .
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Cat. No.: HY-P99624
CAS No.: 944548-38-3
Synonyms: CR4098

Target:  

RABV

Research Areas:  

Infection

Foravirumab (CR4098) is a monoclonal antibody against rabies virus glycoprotein antigenic site III .
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Cat. No.: HY-P4098
CAS No.: 1207092-86-1
SynB1 is a cell-penetrating peptide with blood-brain barrier permeability, derived from the antimicrobial peptide Protegrin 1. SynB1 enhances the cellular uptake efficiency and cytoplasmic localization level of conjugated constructs. SynB1 can be used in studies related to rabies and glioblastoma .
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Cat. No.: HY-158772
Purity:  99.6%
Target:  

DNA/RNA Synthesis

Research Areas:  

Others

m7G(5')ppp(5')(2'OMeA)pU (ammonium) solution (100 mM) is a trinucleotide cap analog with a Cap1 structure. m7G(5')ppp(5')(2'OMeA)pU (ammonium) solution (100 mM) can be co-transcriptionally incorporated into the 5' end of mRNA during T7 RNA polymerase-mediated in vitro transcription to form a natural Cap1 cap structure. m7G(5')ppp(5')(2'OMeA)pU (ammonium) solution (100 mM) enhances mRNA translation efficiency and reduces innate immune recognition, and it has been used in the preparation of self-amplifying mRNA rabies vaccines. m7G(5')ppp(5')(2'OMeA)pU (ammonium) solution (100 mM) can be applied to research related to in vitro mRNA transcription and mRNA vaccines .
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Cat. No.: HY-P99513
CAS No.: 2419087-87-7
Synonyms: CTB011

Target:  

RABV

Research Areas:  

Infection

Zamerovimab (CTB011) is an anti-rabies humanized IgG1κ monoclonal antibody that binds to the non-overlapping epitopes on the rabies virus (RABV) glycoprotein. Zamerovimab targets residues at and near antigenic site III. Zamerovimab can be used in rabies studies .
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Cat. No.: HY-N14107
CAS No.: 146-90-7
Cinnabarin is a natural phenoxazinone red pigment derived from Pycnoporus sanguineus. Cinnabarin reduces rabies virus infection levels in neuroblastoma cells and causes cytopathic effects on neuroblastoma cell monolayers at high concentrations. Cinnabarin exhibits antibacterial activity against bacteria, with a preference for Gram-positive bacteria and human isolates. Cinnabarin can be used in studies related to rabies and drug-resistant Gram-positive bacteria .
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