61 Results for "

random

" in MedChemExpress (MCE) Product Catalog:
Products (61)

61 Results for "random" in MCE Product Catalog:

3
3 Cited Publications
製品番号: HY-B0178A
CAS 番号: 50-01-1
別名: Guanidinium chloride; Aminoformamidine hydrochloride
Guanidine hydrochloride (Guanidinium chloride) is a strong protein denaturant. Guanidine hydrochloride causes proteins to assume a random coil conformation .
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3
3 Cited Publications
製品番号: HY-75958
CAS 番号: 511-28-4
別名: 22-Dihydroergocalciferol
Target:  

VD/VDR

研究分野:  

Metabolic Disease

Vitamin D4 (22-Dihydroergocalciferol) is a Vitamin D derived from fungi. The precursor of Vitamin D4 is 22,23-dihydroergosterol .
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2
2 Cited Publications
製品番号: HY-P3211B
別名: LR12-scr
Target:  

TREM receptor

研究分野:  

Inflammation/Immunology

Nangibotide scrambled peptide (LR12-scr) is a scrambled control peptide composed of the same amino acids from LR12 (Nangibotide; HY-P3211) but in a random sequence (YQDVELCETGED) .
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2
2 Cited Publications
製品番号: HY-P1849A
別名: scJag-1 TFA
Target:  

Notch

研究分野:  

Cardiovascular Disease

JAG-1, scrambled (scJag-1) TFA is a scrambled sequence of JAG-1 (Jagged-1 protein). JAG-1, scrambled TFA has a random sequence of the amino acids that are the same as the active fragment. JAG-1, scrambled TFA is usually used as a negative control .
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1
1 Cited Publications
製品番号: HY-D1668
Biotin-11-dCTP is a biotinylated deoxynucleoside triphosphate and an important DNA labeling reagent. In random primer DNA labeling reactions, Biotin-11-dCTP incorporates into newly synthesized DNA strands to generate labeled DNA probes suitable for hybridization applications. In addition, Biotin-11-dCTP can serve as a substrate for terminal deoxynucleotidyl transferase to end-label oligonucleotides for telomere sequence detection, or to label the cut ends of linearized DNA molecules, thereby supporting streptavidin-based electron microscopy analysis. For example, Biotin-11-dCTP can label the cut ends of linearized DNA molecules under the action of dGTP and avian myeloblastosis virus reverse transcriptase .
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1
1 Cited Publications
製品番号: HY-P10776
CAS 番号: 901117-08-6
Target:  

ペプチド

研究分野:  

Others

RNS peptide is a randomly scrambled control peptide that can be used as a negative control for MANS peptide (HY-P10218) .
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製品番号: HY-P5423
CAS 番号: 107658-43-5
Target:  

Exosomes Liposome

研究分野:  

Cancer

GALA is a pH-responsive amphipathic peptide consisting of 30 amino acids, which acts as a lung endothelium-targeting ligand. GALA undergoes a conformational transition from random coil to α-helix in an acidic environment at pH 5.0, thereby inducing endosomal membrane destabilization and fusion. GALA-modified liposomes traverse lung endothelial cells via clathrin-dependent endocytosis and transcytosis, and specifically accumulate in the lungs after intravenous injection. GALA significantly promotes the cytosolic release of cargos carried by exosomes, plasmids and liposomes, effectively enhances gene transfection efficiency, and drives gene knockdown of functional macromolecules (such as siRNA) in alveolar epithelial cells (with no significant cytotoxicity at effective concentrations). GALA serves as a critical tool for studies on lung cancer metastasis (e.g., melanoma lung metastasis) and lung-targeted drug delivery systems .
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製品番号: HY-D1725
Cy3-dCTP is a directly fluorescently labeled deoxyribonucleotide, in which Cy3 is a cyanine fluorescent dye. Cy3-dCTP is used for direct enzymatic labeling of DNA and cDNA: with the aid of DNA polymerases, this modified nucleotide is incorporated into the extending DNA strand during processes such as reverse transcription, PCR, nick translation or random primer labeling .
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製品番号: HY-E70110
CAS 番号: 37288-54-3
Target:  

Others

研究分野:  

Others

Endo-1,4-β-mannanase is an important catalytic agent that randomly cleave the β-1,4-linkage in the mannan backbone and release short β-1,4-mannooligosaccharides and mannose .
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製品番号: HY-P99845
CAS 番号: 2245953-10-8
別名: MEDI 4920; VIB 4920

Target:  

TNF Receptor

研究分野:  

Inflammation/Immunology

Dazodalibep (MEDI 4920; VIB 4920) is a non-antibody fusion protein that targets CD40L. Dazodalibep inhibits the co-stimulatory signals between immune cells (such as T cells, B cells, and antigen-presenting cells), thereby enabling the inhibition of a broader range of cellular and humoral responses. Dazodalibep can be used for research on rheumatoid arthritis and Sjögren's syndrome .
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製品番号: HY-P2816
CAS 番号: 37278-89-0
研究分野:  

Others

Xylanase is an enzyme targeting 1,4-β-D-xylan that randomly cleaves the β-1,4 backbone of xylan, a complex polysaccharide in plant cell walls. Xylanase finds applications in the food, feed and industrial sectors, including pulp and paper processing, baking, animal feed improvement, and biotransformation of waste .
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製品番号: HY-E70011
CAS 番号: 9041-11-6
研究分野:  

Others

Levanase is a slime-dissolving enzyme of Rhodotorula species. Levanase performs random hydrolysis of β-2,6 fructofuranosyl linkages in β-2,6 fructans containing more than 3 fructose units .
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製品番号: HY-B0178B
CAS 番号: 50-01-1
別名: 6M Guanidinium chloride Solution; 6M Aminoformamidine hydrochloride Solution
6M Guanidine hydrochloride Solution (6M Guanidinium chloride Solution) is a strong protein denaturant. 6M Guanidine hydrochloride Solution causes proteins to assume a random coil conformation .
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製品番号: HY-153840A
純度:  97.03%
研究分野:  

Inflammation/Immunology

ODN INH-18 sodium is a linear 24-mer class B INH-ODN in which the 5' INH-ODN 4084-F sequence was followed by a random stretch of 12 nucleotides lacking the ability to form significant secondary structures. ODN INH-18 sodium showes inhibitory potency for TLR9 ligand-induced IFN-α production.
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製品番号: HY-N8671
CAS 番号: 256520-90-8
Withanoside V is a blood-brain barrier-permeable withanolide derivative . Withanoside V binds strongly to Sudlow I (domain IIA) of human serum albumin (HSA) to form a stable complex and alter the secondary structure of albumin, thereby increasing helix content and reducing β-sheet and random coil. Withanoside V binds to Aβ (1-42) to block the interaction between monomers and subsequent aggregation. Withanoside V inhibits the viability of neuroblastoma cells, reduces the number of apoptotic cells induced by Aβ (1-42), and decreases ROS production. Withanoside V inhibits SARS-CoV-2 Mpro. Withanoside V can be used for research on Alzheimer's disease and coronavirus disease 2019 .
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製品番号: HY-E70185
別名: EC:3.2.1.24; MAN2B1; LAMAN
Lysosomal α-mannosidase (EC:3.2.1.24) is a low pH-activated exoglycosidase that hydrolyzes α-mannosidic linkages on mannan and N-linked oligosaccharides, and its activation requires Zn 2+. As the major exoglycosidase in the glycoprotein degradation pathway, lysosomal α-mannosidase cleaves α1,2-, α1,3- and α1,6-mannosidic linkages during a non-random, ordered degradation process to generate Man1GlcNAc1-2 for further lysosomal processing. Lysosomal α-mannosidase can be used in studies related to α-mannosidosis .
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製品番号: HY-132606C
研究分野:  

Metabolic Disease

Scrambled Nedosiran sodium is a scrambled sequence of Nedosiran sodium (HY-132606A). Scrambled Nedosiran sodium has a random sequence of the amino acids that are the same as the active fragment Nedosiran sodium. Scrambled Nedosiran sodium is usually used as a negative control .
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製品番号: HY-P4114
Target:  

HIV

研究分野:  

Others

TAT-NSF700scr consists the intact TAT domain and glycine linker, followed by the NSF amino acids in a random order. TAT-NSF700scr is used as a control peptide that does not inhibit SNAREmediated exocytosis .
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製品番号: HY-132582D
別名: IONIS-MAPTRx scramble control
Target:  

Tau Protein

研究分野:  

Neurological Disease

Scrambled IONIS-MAPTRx (sodium) is a scrambled sequence of IONIS-MAPTRx sodium (HY-132582C). Scrambled IONIS-MAPTRx (sodium) has the same amino acid composition as the active IONIS-MAPTRx sodium fragment, but the sequence is randomly scrambled. Scrambled IONIS-MAPTRx (sodium) is typically used as a negative control. Scrambled IONIS-MAPTRx (sodium) has potential for studying Alzheimer's disease.
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製品番号: HY-P1138
CAS 番号: 1315378-72-3
別名: FSVYWAQADR
Target:  

Gap Junction Protein

研究分野:  

Others

Scrambled 10Panx (FSVYWAQADR) is a random sequence variant of a specific inhibitory peptide 10Panx targeted at the half-channel of Pannexin-1 (Panx1). Scrambled 10Panx is used as a control peptide to determine whether other experimental conditions or peptides act through specific molecular mechanisms. Scrambled 10Panx can be used for research in neurobiology and cell biology .
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