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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
32 Results for "
recognition specificity
" in MedChemExpress (MCE) Product Catalog:
Products (32)
32 Results for "recognition specificity" in MCE Product Catalog:
10
10 Publications Verification
Synonyms: eFT226
Zotatifin (eFT226) is a potent, selective, and well-tolerated eIF4A inhibitor. Zotatifin promotes eIF4A binding to specific mRNA sequences with recognition motifs in the 5’-UTRs (IC50=2 nM) and interferes with the assembly of the eIF4F initiation complex . Zotatifin shows robust antiviral effects, it effectively reduces viral infectivity by inhibiting SARS-CoV-2 NP protein biogenesis (IC90=37 nM) . Zotatifin induces cell apoptosis .
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1 Cited Publications
Cat. No.: HY-W009444
CAS No.: 1463-10-1
Target:
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1 Cited Publications
Cat. No.: HY-W089845
CAS No.: 629-94-7
Cat. No.: HY-P1745
CAS No.: 163364-16-7
Synonyms: Insulin B chain (9-23)
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Cat. No.: HY-P3732
CAS No.: 332179-76-7
Cat. No.: HY-N10633
CAS No.: 64003-55-0
Synonyms: LS-tetrasaccharide c
Category:
Infection Polysaccharides Endogenous metabolite Disease Research Fields Saccharides Cancer
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Cat. No.: HY-P990981
CAS No.: 2930861-48-4
Synonyms: ALPS-12; RG-6524; RO 7616789
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Synonyms: rel-eFT226
rel-Zotatifin is the racemic isomer of Zotatifin, acts as an eIF4A inhibitor with activity less than Zotatifin. Zotatifin (eFT226) is a potent, selective, and well-tolerated eIF4A inhibitor. Zotatifin promotes eIF4A binding to specific mRNA sequences with recognition motifs in the 5’-UTRs (IC50=2 nM) and interferes with the assembly of the eIF4F initiation complex .
Cat. No.: HY-W014081
CAS No.: 1846-76-0
Synonyms: Ethyl 2-oxo-2H-chromene-3-carboxylate
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Ethyl 3-coumarincarboxylate is a coumarin derivative. Ethyl 3-coumarincarboxylate can be used as a pseudo-template to give a molecularly imprinted polymer (MIP) that has a fairly specific recognition capability for aflatoxins .
Cat. No.: HY-D1262
CAS No.: 1808174-52-8
Synonyms: Thiol-green 2
Cat. No.: HY-160052
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IL-6 aptamer sodium is an aptamer that specifically binds to IL-6, and can serve as a biological recognition receptor for high-sensitivity detection. IL-6 aptamer sodium enables label-free specific detection through changes in electrical signals of carbon nanotube microarrays or alterations in capacitive impedance on the surface of gold sensors. IL-6 aptamer sodium still maintains high selectivity even below the gray zone threshold for cancer diagnosis, and shows no significant non-specific binding to bovine serum albumin. IL-6 aptamer sodium can form an ordered self-assembled monolayer with 6-mercapto-1-hexanol on gold surfaces, making it suitable for reagent-free capacitive impedance biosensing platforms. IL-6 aptamer sodium is widely used in research related to fields such as cancer, inflammatory diseases, myeloma, liver cancer and glioma .
Cat. No.: HY-P10512
CAS No.: 1370451-15-2
0 Images
DNA, 5'-ATCTAACTGCTGCGCCGCCGGGAAAATACTGTACGGTTAGA-3', sodium salt
Cat. No.: HY-160065
Cat. No.: HY-N12962
CAS No.: 123931-40-8
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Cat. No.: HY-D2946
Synonyms: BC-TMR
Cat. No.: HY-146809
CAS No.: 2921603-02-1
Galectin-3 is a β Galactoside specific carbohydrate recognition protein (lectin) has the ability to promote the migration of B cell precursor acute lymphoblastic leukemia (BCP-ALL) cells and withstand drug research.
Cat. No.: HY-122637
CAS No.: 2071636-70-7
Sudemycin K is a selective splicing inhibitor targeting SF3B1. Sudemycin K blocks U2 snRNP recognition of branch point sequences in pre-mRNA, inducing tumor-specific splicing deregulation and apoptosis. Sudemycin K is promising for research of SF3B1-mutated malignancies such as chronic lymphocytic leukemia (CLL) and myelodysplastic syndromes (MDS) .
Cat. No.: HY-W114420
CAS No.: 17028-03-4
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3-Methyl-L-tyrosine is a derivative of L-Tyrosine (HY-N0473). Structurally, 3-Methyl-L-tyrosine features a methyl modification at the third position of the aromatic ring of L-Tyrosine. As a substrate for the protein tyrosine kinase Csk, 3-Methyl-L-tyrosine's relative catalytic efficiency (kcat/Km) is 38% of L-Tyrosine, indicating that the methyl modification impacts the processing efficiency of Gsk significantly. 3-Methyl-L-tyrosine helps to deepen the understanding of Gsk's molecular recognition mechanisms of its substrates, which is crucial for developing specific inhibitors targeting Gsk .
Cat. No.: HY-W089845R
CAS No.: 629-94-7
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
