11 Results for "

redox-sensitive

" in MedChemExpress (MCE) Product Catalog:
Products (11)

11 Results for "redox-sensitive" in MCE Product Catalog:

248
248 Publications Verification
Cat. No.: HY-13948
CAS No.: 4474-91-3
Purity:  99.98%
Synonyms: Angiotensin II; Ang II; DRVYIHPF
Angiotensin II (Angiotensin II) is a vasoconstrictor and a major bioactive peptide of the renin/angiotensin system. Angiotensin II human plays a central role in regulating human blood pressure, which is mainly mediated by interactions between Angiotensin II and the G-protein-coupled receptors (GPCRs) Angiotensin II type 1 receptor (AT1R) and Angiotensin II type 2 receptor (AT2R). Angiotensin II human stimulates sympathetic nervous stimulation, increases aldosterone biosynthesis and renal actions. Angiotensin II human induces growth of vascular smooth muscle cells, increases collagen type I and III synthesis in fibroblasts, leading to thickening of the vascular wall and myocardium, and fibrosis. Angiotensin II human also induces apoptosis. Angiotensin II induces capillary formation from endothelial cells via the LOX-1 dependent redox-sensitive pathway .
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248
248 Publications Verification
Cat. No.: HY-13948A
CAS No.: 68521-88-0
Purity:  99.62%
Synonyms: Angiotensin II acetate; Ang II acetate; DRVYIHPF acetate
Angiotensin II human (Angiotensin II) acetate is a vasoconstrictor and a major bioactive peptide of the renin/angiotensin system. Angiotensin II human acetate plays a central role in regulating human blood pressure, which is mainly mediated by interactions between Angiotensin II and the G-protein-coupled receptors (GPCRs) Angiotensin II type 1 receptor (AT1R) and Angiotensin II type 2 receptor (AT2R). Angiotensin II human acetate stimulates sympathetic nervous stimulation, increases aldosterone biosynthesis and renal actions. Angiotensin II human acetate induces growth of vascular smooth muscle cells, increases collagen type I and III synthesis in fibroblasts, leading to thickening of the vascular wall and myocardium, and fibrosis. Angiotensin II human acetate also induces apoptosis. Angiotensin II human acetate induces capillary formation from endothelial cells via the LOX-1 dependent redox-sensitive pathway .
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248
248 Publications Verification
Cat. No.: HY-13948B
CAS No.: 2761969-44-0
Purity:  98.84%
Synonyms: Angiotensin II TFA; Ang II TFA; DRVYIHPF TFA
Angiotensin II human (Angiotensin II) TFA is a vasoconstrictor and a major bioactive peptide of the renin/angiotensin system. Angiotensin II human TFA plays a central role in regulating human blood pressure, which is mainly mediated by interactions between Angiotensin II and the G-protein-coupled receptors (GPCRs) Angiotensin II type 1 receptor (AT1R) and Angiotensin II type 2 receptor (AT2R). Angiotensin II human TFA stimulates sympathetic nervous stimulation, increases aldosterone biosynthesis and renal actions. Angiotensin II human TFA induces growth of vascular smooth muscle cells, increases collagen type I and III synthesis in fibroblasts, leading to thickening of the vascular wall and myocardium, and fibrosis. Angiotensin II human TFA also induces apoptosis. Angiotensin II human TFA induces capillary formation from endothelial cells via the LOX-1 dependent redox-sensitive pathway .
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2
2 Cited Publications
Cat. No.: HY-D0016
CAS No.: 90217-02-0
Synonyms: CTC
5-Cyano-2,3-di-(p-tolyl)tetrazolium chloride (CTC) is a redox-sensitive red fluorescent dye. 5-Cyano-2,3-di-(p-tolyl)tetrazolium chloride can be used for detecting metabolic activity in microorganisms. The emission maximum of 5-Cyano-2,3-di-(p-tolyl)tetrazolium chloride is 602 nm .
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1
1 Cited Publications
Cat. No.: HY-Y0678
CAS No.: 621-23-8
Synonyms: TRIMETHYL PHLOROGLUCINOL
1,3,5-Trimethoxybenzene (TRIMETHYL PHLOROGLUCINOL) is an electrophilic substitution reaction substrate targeting free chlorine (Cl +) and free bromine (Br +). 1,3,5-Trimethoxybenzene has highly selective electrophilic addition characteristics. By capturing halogens, it undergoes specific substitution reactions to generate stable halogenated products. 1,3,5-Trimethoxybenzene can not only quench residual oxidants, but also quantify the halogen concentration by detecting the product without affecting the stability of redox-sensitive disinfection byproducts (DBPs). 1,3,5-Trimethoxybenzene is mainly used in water quality testing and quantitative analysis of free chlorine/bromine in water. At the same time, in phytochemistry, it is a key component of rose fragrance and participates in the study of pollination attraction mechanism .
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1
1 Cited Publications
Cat. No.: HY-12809
CAS No.: 348575-88-2
Purity:  99.81%
Target:  

TRP Channel

Research Areas:  

Neurological Disease

Optovin is a reversible photoactivated TRPA1 ligand that enables light-mediated neuronal excitation. Optovin activates TRPA1 via structure-dependent photochemical reactions with redox-sensitive cysteine residues .
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Cat. No.: HY-178078
CAS No.: 1800077-28-4
Target:  

Drug Intermediate

Research Areas:  

Cancer

PTX-SS-COOH is the proform that can be grafted to the sulfhydryl modified gelatin to form the redox sensitive amphiphilic polymer. The nanoparticle (BSA/Gel-SS-PTX/PTX-SS-COOH NPs) demonstrates an excellent anticancer efficiency. PTX-SS-COOH can be applied in the research of targeted delivery for solid tumors (such as breast cancer and melanoma) by utilizing the unique characteristics of the tumor microenvironment (high GSH level) .
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Cat. No.: HY-Y0678R
CAS No.: 621-23-8
1,3,5-Trimethoxybenzene (TRIMETHYL PHLOROGLUCINOL) is an electrophilic substitution reaction substrate targeting free chlorine (Cl+) and free bromine (Br+). 1,3,5-Trimethoxybenzene has highly selective electrophilic addition characteristics. By capturing halogens, it undergoes specific substitution reactions to generate stable halogenated products. 1,3,5-Trimethoxybenzene can not only quench residual oxidants, but also quantify the halogen concentration by detecting the product without affecting the stability of redox-sensitive disinfection byproducts (DBPs). 1,3,5-Trimethoxybenzene is mainly used in water quality testing and quantitative analysis of free chlorine/bromine in water. At the same time, in phytochemistry, it is a key component of rose fragrance and participates in the study of pollination attraction mechanism .
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Cat. No.: HY-N15449
CAS No.: 33211-22-2
Vicanicin is a depsidone compound found in lichens. Vicanicin inhibits the expression of Hsp70, regulates the redox-sensitive mechanisms within cells, promotes the increase of reactive oxygen species (ROS) in cancer cells, changes the Bax/Bcl-2 ratio, activates caspase-3, and triggers apoptosis. Vicanicin inhibits cell growth and induces apoptosis in androgen-sensitive (LNCaP) and androgen-insensitive (DU-145) human prostate cancer cells. Vicanicin is promising for research of prostate cancer .
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Cat. No.: HY-139995
CAS No.: 2576358-68-2
Target:  

Drug Intermediate

Research Areas:  

Others

Spermine precursor-1 (Compound 1) is a redox-sensitive spermine precursor for the potential research of snyder robinson syndrome. Spermine precursor-1 inhibits wild-type (CMS-24949) and spermine synthase gene (SMS) mutant (CMS-26559, and CMS-6233) fibroblast cells with IC50s of 326.7, 198.5, and 244.1 μM, respectively .
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Cat. No.: HY-149246
CAS No.: 3043752-01-5
Aβ-IN-6 reduces pro-inflammatory cytokine release from microglia cells. Aβ-IN-6 significantly induces Nrf2 nuclear translocation and hamperes Aβ oligomers formation. Aβ-IN-6 exerts a consistent neuroprotective effect by modulating the redox-sensitive signalling pathways in vivo oxidative stress model. Aβ-IN-6 is an orally active and has antiinflammatory, Antioxidant and Anti-oligomeric activity. Aβ-IN-6 has the potential for Alzheimer's disease (AD) research .
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