84 Results for "

removal

" in MedChemExpress (MCE) Product Catalog:
Products (84)

84 Results for "removal" in MCE Product Catalog:

25
25 Publications Verification
Cat. No.: HY-107425
CAS No.: 1797406-69-9
Purity:  99.86%
Research Areas:  

Cancer

MZ 1 is a PROTAC connected by ligands for von Hippel-Lindau and BRD4. MZ 1 potently and rapidly induces reversible, long-lasting, and selective removal of BRD4 over BRD2 and BRD3. Kds of 382/120, 119/115, and 307/228 nM for BRD4 BD1/2, BRD3 BD1/2, and BRD2 BD1/2, respectively .
loading...
    loading...
5
5 Cited Publications
Cat. No.: HY-N0667
CAS No.: 70-47-3
Synonyms: (-)-Asparagine; Asn; Asparamide
L-Asparagine is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia .
loading...
    loading...
5
5 Cited Publications
Cat. No.: HY-W017443
CAS No.: 5794-13-8
L-Asparagine monohydrate is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine monohydrate can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia .
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-106783
CAS No.: 86408-36-8
Purity:  99.82%
Target:  

Bacterial Antibiotic

Research Areas:  

Infection

Polymyxin B nonapeptide is a cyclic peptide obtained from Polymyxin B by proteolytic removal of its terminal amino acyl residue. Polymyxin B nonapeptide is less toxic, lacks bactericidal activity, and retains its ability to render gram-negative bacteria susceptible to several antibiotics by permeabilizing their outer membranes .
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-Y0850E
CAS No.: 9002-89-5
Synonyms: PVA (Mw 30000-70000, 87-90% hydrolyzed); Poly(Ethenol) (Mw 30000-70000, 87-90% hydrolyzed)
Polyvinyl alcohol (Mw 30000-70000, 87-90% hydrolyzed) is a polyvinyl alcohol with a molecular weight of 30000-70000 and hydrolytic properties. The degree of hydrolysis refers to the degree to which the acetate groups in the original polyvinyl acetate are converted into hydroxyl groups during the hydrolysis process. Polyvinyl alcohol (Mw 30000-70000, 87-90% hydrolyzed) is the hydrolysis and removal of acetate groups after the polymerization of ethylene acetate. And polyvinyl alcohol is obtained. A degree of hydrolysis of 87-90% indicates that a large part of the acetate groups have been removed, resulting in a large number of hydroxyl groups in the PVA structure. Polyvinyl alcohol with different degrees of hydrolysis can be used to self-crosslink to form cryogel, which can be used as biological excipients .
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-Y0850J
CAS No.: 9002-89-5
Synonyms: PVA (Mw 13000-23000, 87-89% hydrolyzed); Poly(Ethenol) (Mw 13000-23000, 87-89% hydrolyzed)
Polyvinyl alcohol (Mw 13000-23000, 87-89% hydrolyzed) is a polyvinyl alcohol with a molecular weight of 130000-23000 and hydrolytic properties. Polyvinyl alcohol (Mw 13000-23000, 87-89% hydrolyzed) is the hydrolysis and removal of acetate groups after the polymerization of ethylene acetate and polyvinyl alcohol is obtained. A degree of hydrolysis of 87-89% indicates that a large part of the acetate groups have been removed, resulting in a large number of hydroxyl groups in the PVA structure. Polyvinyl alcohol with different degrees of hydrolysis can be used to self-crosslink to form cryogel, which can be used as biological excipient. Polyvinyl alcohol can be used in tissue engineering by electrospinning. Polyvinyl alcohol can achieve high cellular density, infiltration, and uniform distribution, facilitating functional connections between cells. Polyvinyl alcohol can improve cell vitality through in vitro cultivation. Polyvinyl alcohol demonstrates promising inhibition of ostersarcoma cancer cells with Doxorubicin (HY-15142A) .
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-Y0850M
CAS No.: 9002-89-5
Synonyms: PVA (Mw 85000-124000, 87-89% hydrolyzed); Poly(Ethenol) (Mw 85000-124000, 87-89% hydrolyzed)
Polyvinyl alcohol (Mw 85000-124000, 87-89% hydrolyzed) is a polyvinyl alcohol with a molecular weight of 85000-124000 and hydrolytic properties. The degree of hydrolysis refers to the degree to which the acetate groups in the original polyvinyl acetate are converted into hydroxyl groups during the hydrolysis process. Polyvinyl alcohol (Mw 85000-124000, 87-89% hydrolyzed) is the hydrolysis and removal of acetate groups after the polymerization of ethylene acetate. And polyvinyl alcohol is obtained. A degree of hydrolysis of 87-89% indicates that a large part of the acetate groups have been removed, resulting in a large number of hydroxyl groups in the PVA structure. Polyvinyl alcohol with different degrees of hydrolysis can be used to self-crosslink to form cryogel, which can be used as biological excipient .
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-Y0850P
CAS No.: 9002-89-5
Synonyms: PVA (Mw 146000-186000, 87-89% hydrolyzed); Poly(Ethenol) (Mw 146000-186000, 87-89% hydrolyzed)
Polyvinyl alcohol (Mw 146000-186000, 87-89% hydrolyzed) is a polyvinyl alcohol with a molecular weight of 146000-186000 and hydrolytic properties. Polyvinyl alcohol (Mw 146000-186000, 87-89% hydrolyzed) is the hydrolysis and removal of acetate groups after the polymerization of ethylene acetate. And polyvinyl alcohol is obtained. Polyvinyl alcohol with different degrees of hydrolysis can be used to self-crosslink to form cryogel, which can be used as biological excipient. Polyvinyl alcohol can be used in tissue engineering by electrospinning. Polyvinyl alcohol can achieve high cellular density, infiltration, and uniform distribution, facilitating functional connections between cells. Polyvinyl alcohol can improve cell vitality through in vitro cultivation. Polyvinyl alcohol demonstrates promising inhibition of ostersarcoma cancer cells with Doxorubicin (HY-15142A) .
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-106783A
CAS No.: 2220175-42-6
Purity:  99.79%
Target:  

Bacterial Antibiotic

Research Areas:  

Infection

Polymyxin B nonapeptide TFA is a cyclic peptide obtained from Polymyxin B by proteolytic removal of its terminal amino acyl residue. Polymyxin B nonapeptide TFA is less toxic, lacks bactericidal activity, and retains its ability to render gram-negative bacteria susceptible to several antibiotics by permeabilizing their outer membranes .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-13755A
CAS No.: 142825-10-3
Purity:  99.48%
Synonyms: L-Sulforaphane
(R)-Sulforaphane (L-Sulforaphane) is a orally active, potent inducer of the Keap1/Nrf2/ARE pathway, exhibiting antioxidant and anticancer activities. (R)-Sulforaphane primarily functions by upregulating phase II detoxifying enzymes in cells, aiding in the removal of carcinogens and combating oxidative stress. (R)-Sulforaphane is capable of modulating gene expression, influencing various signaling pathways, including Nrf2, NF-κB, and AP-1. (R)-Sulforaphane can be used in studies of tumor biology, antioxidant defense mechanisms, as well as inflammation and immune responses .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-B1827
CAS No.: 91510-62-2
Synonyms: D-galUA hydrate
D-Galacturonic acid (D-galUA) hydrate, as the main component of pectin, is abundantly present in plants. The carboxyl group of D-Galacturonic acid hydrate can bind to metal cations. D-Galacturonic acid hydrate plays an important role in the food industry, pharmaceutical field, and heavy metal removal, among other aspects .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-B1827A
CAS No.: 685-73-4
Synonyms: D-galUA
D-Galacturonic acid (D-galUA), as the main component of pectin, is abundantly present in plants. The carboxyl group of D-Galacturonic acid can bind to metal cations. D-Galacturonic acid plays an important role in the food industry, pharmaceutical field, and heavy metal removal, among other aspects .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-N0667S2
CAS No.: 287484-32-6
Synonyms: (-)-Asparagine-15N2 monohydrate; Asn-15N2 monohydrate; Asparamide-15N2 monohydrate
L-Asparagine- 15N2 monohydrate is the 15N-labeled L-Asparagine monohydrate (HY-W017443). L-Asparagine monohydrate is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine monohydrate can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-B0824
CAS No.: 82657-04-3
Bifenthrin is a synthetic pyrethroid insecticide. Bifenthrin prolongs the opening time of Nav1.8 sodium channels, leading to membrane depolarization and conductance block in the insect nervous system, thereby disrupting neural function. Bifenthrin was effective in inhibiting A. gambiae (LD50=0.15 ng/mg) and C. quinquefasciatus (LD50=0.16 ng/mg). Bifenthrin has good lethality against susceptible and resistant mosquitoes and is very effective in inhibiting blood sucking and can be developed as a mosquito-removal netting material .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-B1299
CAS No.: 61-24-5
Target:  

Bacterial

Research Areas:  

Infection

Cephalosporin C has weak resistance to Gram-positive and negative bacteria, is stable to penicillinase, and can be broken down by cephalosporin enzyme. Hydrolysis and removal of side chains to obtain 7-amino-cefenoic acid (7-ACA) is an important raw material for the preparation of semi-synthetic cephalosporin .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-N0667S5
CAS No.: 2483831-59-8
L-Asparagine-d3 hydrate is the deuterium labeled L-Asparagine (HY-N0667). L-Asparagine is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-B1827R
CAS No.: 91510-62-2
Synonyms: D-galUA hydrate (Standard)
D-Galacturonic acid hydrate (Standard) (D-galUA hydrate (Standard)) is the analytical standard of D-Galacturonic acid hydrate (HY-B1827). This product is intended for research and analytical applications. D-Galacturonic acid (D-galUA) hydrate, as the main component of pectin, is abundantly present in plants. The carboxyl group of D-Galacturonic acid hydrate can bind to metal cations. D-Galacturonic acid hydrate plays an important role in the food industry, pharmaceutical field, and heavy metal removal, among other aspects.
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-K3010

MCE Red Blood Cell Lysis Buffer (10×) primarily contains ammonium chloride and is a ready-to-use solution designed for rapid and effective lysis and removal of anucleated red blood cells from human or mouse blood and tissue samples without affecting white blood cells, normal tissues, or tumor cells.

loading...
    loading...
Cat. No.: HY-N1442
CAS No.: 633-96-5
Synonyms: Orange II; D&C Orange NO. 4
Acid Orange 7 (Orange II; D&C Orange NO. 4) is an azo dye widely used in the textile, food and cosmetic industries. Acid Orange 7 is mainly used as a colorant by combining with fibers and other substances through azo bonds. Acid Orange 7 has a maximum absorption wavelength at 484-485 nm, and the concentration is measured using a UV-visible spectrophotometer. Acid Orange 7 is difficult to degrade and has a certain degree of toxicity. It is often used to study various sewage treatment technologies and photocatalytic degradation reactions, and to evaluate the removal effects of different treatment methods on organic pollutants .
loading...
    loading...
Cat. No.: HY-141633
CAS No.: 25339-99-5
Purity:  ≥97.0%
Sucrose monolaurate is a glycolipid surfactant . Sucrose monolaurate interacts with bacterial DNA, disrupts cell membrane permeability, and exerts excellent inhibitory and bactericidal effects against a variety of foodborne pathogens (especially Gram-positive bacteria). Sucrose monolaurate significantly reduces liquid surface tension, and acts as a synergist for chlorine-based disinfectants in food cleaning and disinfection to improve the removal efficiency of pathogens on the surface of agricultural products .
loading...
    loading...