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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
36 Results for "
snake
" in MedChemExpress (MCE) Product Catalog:
Products (36)
36 Results for "snake" in MCE Product Catalog:
11
11 Cited Publications
Cat. No.: HY-P1902
CAS No.: 115722-23-1
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11
11 Cited Publications
Cat. No.: HY-P1902A
CAS No.: 2918768-05-3
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Cat. No.: HY-P1189
CAS No.: 154303-05-6
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Cat. No.: HY-158082B
Synonyms: Tetramethyl rhodamine isothiocyanate glucan, MW 40000
Category:
Plants Compositae Infection Flavonoids Deguelia rufescens (Benth.) R.A.Camargo & A.M.G.Azevedo Flavonones Phenols Polyphenols Disease Research Fields Inflammation/Immunology
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Cat. No.: HY-137799
CAS No.: 55894-52-5
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NOBA is a synthetic chromogenic substrate that can be used to detect the enzyme activity of AplTX-II. NOBA can be used in the research of phospholipid hydrolysis .
Cat. No.: HY-P1189A
Category:
Natural Products Animals Metabolic Disease Disease Research Fields Inflammation/Immunology
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Cat. No.: HY-W013741
CAS No.: 2491-17-0
Cat. No.: HY-120078
CAS No.: 1845753-81-2
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AZD2716 is an orally active secretory phospholipase A2 (sPLA2) inhibitor. AZD2716 inhibits human GIIA sPLA2 (IC50=10 nM), human GV sPLA2 (IC50=40 nM), human GX sPLA2 (IC50=400 nM), snake venom sPLA2 (IC50=2 pM), and snake (Bothrops jararacussu) Lys49-PLA2-like toxin (Kd=110 μM). AZD2716 inhibits sPLA2 isoforms IIa, V, X, snake venom sPLA2s, and snake venom Lys49-PLA2-like toxin myotoxic activity via hydrophobic channel binding. AZD2716 suppresses GIIA sPLA2 production, neutralizes snake venom-induced myotoxicity, and improves survival in envenomed mice. AZD2716 can be used for the research of coronary artery disease, atherosclerosis, and snakebite envenoming .
Cat. No.: HY-B2119
CAS No.: 41945-48-6
Synonyms: Tauroglycocholic acid sodium salt
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Sodium tauroglycocholate (Tauroglycocholic acid sodium salt) is a multifunctional surfactant and penetration enhancer that can serve as a cholegraphic contrast agent. In organic solvents, Sodium tauroglycocholate embeds and stabilizes invertase by forming reverse micelles, and prolongs its active lifespan. In terms of transdermal absorption, Sodium tauroglycocholate effectively regulates the flux of aminophylline through snake slough by binding to keratin filaments, disrupting keratinocytes and altering lipid components of the stratum corneum. It exhibits rapid penetration characteristics without lag time at a concentration of 100 μg/mL. Sodium tauroglycocholate does not interfere with the hepatic uptake of Gd-EOB-DTPA by the bile acid transport system in rat hepatocytes .
Cat. No.: HY-P3269
CAS No.: 178805-91-9
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Cat. No.: HY-P3055A
Synonyms: DTX-I TFA
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Cat. No.: HY-P5833
CAS No.: 124511-67-7
Synonyms: κ-Bgt
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Cat. No.: HY-P3055
CAS No.: 107950-33-4
Synonyms: DTX-I
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Cat. No.: HY-23909
CAS No.: 89560-01-0
Synonyms: DEDA
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7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid (DEDA), a phospholipase inhibitor, is a non-metabolizable analog of arachidonic or eicosadienoic acid. 7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid (DEDA) inhibits P388D1 cell phospholipase A2 (PLA2) (IC50 = 16 µM) and snake venom PLA2 (IC50 = 14 µM) .
Cat. No.: HY-P11214
CAS No.: 2243975-43-9
Synonyms: H-TL1
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Cat. No.: HY-P10431
CAS No.: 1801534-21-3
Synonyms: Sea snake cathelicidin
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Cat. No.: HY-P5835
CAS No.: 189201-23-8
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Cat. No.: HY-P5857
Synonyms: Micrurotoxin 2
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
