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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
22 Results for "
translation efficiency
" in MedChemExpress (MCE) Product Catalog:
Products (22)
22 Results for "translation efficiency" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-W019670
CAS No.: 3768-18-1
1
Target:
1
1 Cited Publications
Cat. No.: HY-153083
COVID-19 Spike Protein mRNA (N1-Me-Pseudo UTP) is an mRNA encoding the SARS-CoV-2 spike protein with enhanced performance via chemical modification. COVID-19 Spike Protein mRNA (N1-Me-Pseudo UTP) replaces natural uridine (UTP) with N1-Me-Pseudo UTP, which effectively reduces immunogenicity and improves stability and translation efficiency. The 3' UTR of COVID-19 Spike Protein mRNA (N1-Me-Pseudo UTP) optimizes AU-rich elements through HuR anchor sites, exhibiting higher translation efficiency. COVID-19 Spike Protein mRNA is widely used in COVID-19-related scientific research and vaccine development .
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1 Cited Publications
Cat. No.: HY-153229
Synonyms: m7G(5')ppp(5')(2'OMeA)pG ammonium
Cat. No.: HY-153235
Cat. No.: HY-153232
Cat. No.: HY-153108
Purity: 99.62%
Synonyms: ARCA cap solution (100 mM)
Research Areas:
N6,2′-O-Dimethyladenosine is a FTO substrate and reversible RNA modification. N6,2′-O-Dimethyladenosine acts as a demethylation substrate for FTO, which removes its methyl groups. N6,2′-O-Dimethyladenosine correlates with enhanced mRNA stability, improved translation efficiency and increased protein expression levels. N6,2′-O-Dimethyladenosine is applicable to research related to obesity and colorectal cancer .
Cat. No.: HY-W753593
Cat. No.: HY-153231A
Cat. No.: HY-W019670R
CAS No.: 3768-18-1
Category:
Cat. No.: HY-145974
CAS No.: 62858-30-4
Synonyms: m7G(5')ppp(5')(2'OMeA)pG
Research Areas:
m7GpppAmpG (m7G(5')ppp(5')(2'OMeA)pG) is a trinucleotide 5′ cap analog. m7GpppAmpG binds to eIF4E with a KD value of 45.6 nM. m7GpppAmpG caps RNA with an efficiency of 90% and enhances mRNA stability and translation efficiency. m7GpppAmpG is used in mRNA therapeutic research .
Cat. No.: HY-E70081
Target:
Research Areas:
mRNA Cap 2'-O-methyltransferase uses S-adenosylmethionine (SAM) as a methyl donor to add a methyl group at the 2'-O position of the first nucleotide at the 5’ end of Cap-0 mRNA, resulting in Cap-1 structure. Cap-1 structure promotes translation efficiency, increasing subsequent protein expression .
Cat. No.: HY-164984
CAS No.: 123212-19-1
Target:
Research Areas:
m3227G(5)ppp(5')A is a specific mRNA molecule structure, which is composed of a 3227-methylguanine (m3227G) cap, a triphosphate group and an adenosine. m3227G(5)ppp(5')A affects the stability and translation efficiency of mRNA .
Cat. No.: HY-145976
CAS No.: 133608-76-1
Research Areas:
m7GpppGpG is an unmodified trinucleotide cap analog with enhancer activity. When incorporated into mRNA, it effectively enhances translational efficiency, stability, and protein expression levels of the mRNA. m7GpppGpG can serve as a standard cap analog for in vitro mRNA synthesis to support antigen generation and presentation by dendritic cells, although its expression efficiency in dendritic cells is 20-fold lower than that of the m7GpppApG cap .
Cat. No.: HY-W011209R
CAS No.: 7724-76-7
Synonyms: Riboprine (Standard)
Category:
Cat. No.: HY-153230
Cat. No.: HY-164984A
Target:
Research Areas:
m3227G(5)ppp(5')A triammonium is the triammonium salt form of m3227G(5)ppp(5')A (HY-164984). m3227G(5)ppp(5')A triammonium is a specific mRNA molecule structure, which is composed of a 3227-methylguanine (m3227G) cap, a triphosphate group and an adenosine. m3227G(5)ppp(5')A triammonium affects the stability and translation efficiency of mRNA .
Cat. No.: HY-K6021
MCE CEPT Cocktail Plus (1000×) is a composite supplement specifically formulated for pluripotent stem cell culture. Through synergistic effects, it inhibits oxidative damage, blocks apoptotic pathways, and regulates protein translation, significantly reducing cellular stress levels through multiple targets. This dramatically improves the survival rate and cloning efficiency of pluripotent stem cells.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
