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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
39 Results for "
voltage-sensitive
" in MedChemExpress (MCE) Product Catalog:
Products (39)
39 Results for "voltage-sensitive" in MCE Product Catalog:
18
18 Publications Verification
9
Research Areas:
Topiramate (McN 4853) is a broad-spectrum antiepileptic agent. Topiramate is a GluR5 receptor antagonist. Topiramate produces its antiepileptic effects through enhancement of GABAergic activity, inhibition of kainate/AMPA receptors, inhibition of voltage-sensitive sodium and calcium channels, increases in potassium conductance, and inhibition of carbonic anhydrase .
6
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Research Areas:
Mirogabalin (DS-5565) is a novel, preferentially selective α2δ-1 ligand characterized by high potency and selectivity to the α2δ-1 subunit of voltage-sensitive calcium channel complexes in the CNS.
3
3 Cited Publications
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Research Areas:
PD173212 is a selective N-type voltage sensitive calcium channel (VSCC) blocker, with an IC50 of 36 nM in IMR-32 assays.
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1
1 Cited Publications
1
Research Areas:
Tetracaine hydrochloride (Amethocaine hydrochloride) is a calcium channel protein inhibitor and blocks voltage-sensitive release of Ca 2+ from sarcoplasmic reticulum. Tetracaine hydrochloride is mainly used topically in ophthalmology and as an antipruritic .
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Target:
Cat. No.: HY-D1092
CAS No.: 63560-89-4
Cat. No.: HY-DY1039
CAS No.: 70363-83-6
Solvent and concentration: DMSO: 10 mM
Target:
Cat. No.: HY-12650S1
Synonyms: DS5565-d4
Cat. No.: HY-B0122R
CAS No.: 97240-79-4
Synonyms: McN 4853 (Standard); RWJ 17021 (Standard)
Target:
Reference Standards iGluR GABA Receptor Sodium Channel Calcium Channel Potassium Channel Carbonic Anhydrase
Research Areas:
Topiramate (Standard) is the analytical standard of Topiramate. This product is intended for research and analytical applications. Topiramate (McN 4853) is a broad-spectrum antiepileptic agent. Topiramate is a GluR5 receptor antagonist. Topiramate produces its antiepileptic effects through enhancement of GABAergic activity, inhibition of kainate/AMPA receptors, inhibition of voltage-sensitive sodium and calcium channels, increases in potassium conductance, and inhibition of carbonic anhydrase .
Cat. No.: HY-P3269
CAS No.: 178805-91-9
Target:
Research Areas:
Cat. No.: HY-D1512
CAS No.: 88969-31-7
Cat. No.: HY-B0122S
Synonyms: McN 4853-13C6; RWJ 17021-13C6
Cat. No.: HY-114958
CAS No.: 107610-19-5
Cat. No.: HY-110234
CAS No.: 1279037-95-4
Synonyms: McN 4853 D12 ; RWJ 17021 D12
Research Areas:
Topiramate D12 (McN 4853 D12) is a deuterium labeled Topiramate. Topiramate is a broad-spectrum antiepileptic agent. Topiramate is a GluR5 receptor antagonist. Topiramate produces its antiepileptic effects through enhancement of GABAergic activity, inhibition of kainate/AMPA receptors, inhibition of voltage-sensitive sodium and calcium channels, increases in potassium conductance, and inhibition of carbonic anhydrase .
Cat. No.: HY-W042039
CAS No.: 15964-79-1
Target:
Research Areas:
Methyl homoveratrate, a metabolite of RWJ-26240 in vivo, can be identified in plasma, urine and faecal extract. McN5691 (RWJ-26240) is a voltage-sensitive calcium channel blocker .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
