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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
212 Results for "
zinc finger protein
" in MedChemExpress (MCE) Product Catalog:
Products (212)
212 Results for "zinc finger protein" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-P70039
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CTCF; CFAP108; CCCTC-Binding Factor; FAP108; Transcriptional Repressor CTCF; CCCTC-Binding Factor (zinc finger protein); 11-zinc finger protein; 11 zinc finger Transcriptional Repressor; CTCFL Paralog; MRD21
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P70310
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: EGR1; TIS8; Early Growth Response 1; Transcription Factor Zif268; NGFI-A; zinc finger protein Krox-24; AT225; zinc finger protein 225; Nerve Growth Factor-Induced protein A; zinc finger Gene 225; Early Growth Response protein 1; ZNF225; Transcription Fact
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P83731
Synonyms: Gli 1; Gli1; Gli-1; GLI; GLI Kruppel family member 1; Glioma associated oncogene; Glioma associated oncogene homolog 1 (zinc finger protein); Oncogene GLI; Zfp 5; Zfp5; zinc finger protein GLI 1; zinc finger protein GLI1; GLI1_HUMAN.
1
1 Cited Publications
Cat. No.: HY-P86929
Synonyms: Histone acetyltransferase KAT6A EC:2.3.1.48 MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3 (MYST-3) Monocytic leukemia zinc finger protein Runt-related transcription factor-binding protein 2 zinc finger protein 220 KAT6A MOZ MYST3 RUNXBP2 Histone acetyltransferase KAT6A EC:2.3.1.48 MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3 (MYST-3) Monocytic leukemia zinc finger protein Runt-related transcription factor-binding protein 2 zinc finger protein 220 KAT6A MOZ MYST3 RUNXBP2 ZNF220
1
1 Cited Publications
Target:
Research Areas:
Cisd2 agonist 2 (compound 6) is a Cisd2 activator (EC50=191 nM), and Cisd2 levels are associated with non-alcoholic fatty liver disease (NAFLD). Cisd2 agonist 2 has no significant in vivo toxicity in Cisd2hKO-het mice (heterozygous hepatocyte-specific Cisd2 knockout). Cisd2 (CDGSH iron sulfur domain 2) is a zinc finger protein that is mainly localized in the endoplasmic reticulum or mitochondrial membrane. Cisd2 participates in mitochondrial function by forming homodimers containing two redox-active 2Fe-2S clusters .
1
1 Cited Publications
Cat. No.: HY-P76262
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CISD1; CDGSH Iron-Sulfur Domain-Containing protein 1; Prev. C10orf70; Chromosome 10 Open Reading Frame 70; Prev. ZCD1; zinc finger, CDGSH-Type Domain 1; MitoNEET; zinc finger CDGSH-Type Domain 1; MDS029; CDGSH Iron Sulfur Domain 1; Cysteine Transaminase C
Species:
Human
Source:
E. coli
1
1
1 Cited Publications
Cat. No.: HY-P702076
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: RBCK1; Hepatitis B Virus X-Associated protein 4; Prev. C20orf18; RING finger protein 54; UBCE7IP3; HOIL-1; RNF54; XAP3; XAP4; CDNA FLJ60704, Highly Similar To RanBP-Type And C3HC4-Type zincfinger-Containing protein 1; RanBP-Type And C3HC4-Type zinc finger
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P81125
Synonyms: MGC126598 antibody;
Osterix antibody;
Osx antibody;
Sp 7 antibody;
SP7 antibody;
Sp7 transcription factor antibody;
SP7_HUMAN antibody;
Transcription factor Sp7 antibody;
zinc finger protein osterix antibody;
1
1 Cited Publications
Cat. No.: HY-P76079
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SMYD2; Histone Methyltransferase SMYD2; SET And MYND Domain Containing 2; ZMYND14; HSKM-B; Lysine N-Methyltransferase 3C; KMT3C; [Histone H3]-Lysine(4) N-Trimethyltransferase; SET And MYND Domain-Containing protein 2; zinc finger, MYND Domain Containing 1
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-160695
CAS No.: 2924858-25-1
Target:
Research Areas:
PT-179 is an orthogonal Thalidomide (HY-14658) derivative that targets cereblon without causing off-target degradation effects. PT-179 is able to specifically bind CRBN, form a ternary complex with a target protein fused to a zinc finger (ZF) degron, and mediate the degradation of the tagged protein. For example, PT-179 binds to the ubiquitin ligase substrate receptor cereblon by forming a complex with SD40 and efficiently degrades proteins N- or C-terminally fused to SD40 or SD36 (DC50 for eGFP: 4.5 nM and 14.3 nM). PT-179 can be used to develop compact protein degradation tagging platforms .
Cat. No.: HY-178683
CAS No.: 2438125-72-3
ALV-05-077-01 is a BCL6/BCL6B degrader. ALV-05-077-01 binds to CRBN and recruits specific zinc finger proteins as neo-substrates for ubiquitination and proteasomal degradation. ALV-05-077-01 induces the degradation of full-length endogenous BCL6 zinc finger protein. ALV-05-077-01 induces the degradation of full-length endogenous BCL6B zinc finger protein. ALV-05-077-01 can be used in the research of hematological malignancies .
Cat. No.: HY-178700
CAS No.: 2744249-11-2
ALV-05-151-02 is a BCL6B zinc finger protein degrader that selectively targets BCL6B over BCL6. ALV-05-151-02 redirects the E3 ubiquitin ligase CRL4CRBN to induce BCL6B degradation and interacts with the H357 residue of BCL6B .
Cat. No.: HY-120264
CAS No.: 1964457-41-7
Target:
Research Areas:
YPC-22026 is a zinc-finger protein 143 (ZNF143) inhibitor with an IC50 value of 9.0 μM. YPC-22026 is a potent tumor regression inducer. YPC-22026 exhibits anti‐tumor activities .
Cat. No.: HY-174673
Human GATA4 mRNA encodes the human GATA binding protein 4 (GATA4) protein, a member of the GATA family of zinc-finger transcription factors. GATA4 is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function. It is also necessary for normal testicular development.
Cat. No.: HY-174676
Human GATA2 mRNA encodes the human GATA binding protein 2 (GATA2) protein, a member of the GATA family of zinc-finger transcription factors. GATA2 plays an essential role in regulating transcription of genes involved in the development and proliferation of hematopoietic and endocrine cell lineages.
Cat. No.: HY-P81282AA
Synonyms: CLL associated antigen KW 6; DNA-binding protein Ikaros; hIk 1; hIk-1; Hs.54452; IK1; Ikaros (zinc finger protein); IKAROS; IKAROS family zinc finger 1 (Ikaros); Ikaros family zinc finger protein 1; Ikzf1; IKZF1_HUMAN; LYF1; Lymphoid transcription factor LyF-1; PRO0758; zinc finger protein subfamily 1A 1 (Ikaros); zinc finger protein subfamily 1A 1; zinc finger protein; subfamily 1A; member 1; ZNFN1A1.
Cat. No.: HY-P81282A
Synonyms: CLL associated antigen KW 6; DNA-binding protein Ikaros; hIk 1; hIk-1; Hs.54452; IK1; Ikaros (zinc finger protein); IKAROS; IKAROS family zinc finger 1 (Ikaros); Ikaros family zinc finger protein 1; Ikzf1; IKZF1_HUMAN; LYF1; Lymphoid transcription factor LyF-1; PRO0758; zinc finger protein subfamily 1A 1 (Ikaros); zinc finger protein subfamily 1A 1; zinc finger protein; subfamily 1A; member 1; ZNFN1A1.
Cat. No.: HY-P85524
Synonyms: CLL associated antigen KW 6; DNA-binding protein Ikaros; hIk 1; hIk-1; Hs.54452; IK1; Ikaros; zinc finger protein; IKAROS; IKAROS family zinc finger 1; Ikaros; Ikaros family zinc finger protein 1; Ikzf1; IKZF1_HUMAN; LYF1; Lymphoid transcription factor LyF-1; PRO0758; zinc finger protein subfamily 1A 1; Ikaros; zinc finger protein subfamily 1A 1; zinc finger protein, subfamily 1A, member 1; ZNFN1A1.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
