1. Metabolic Enzyme/Protease Immunology/Inflammation
  2. FLAP Epoxide Hydrolase
  3. sEH/FLAP-IN-1

sEH/FLAP-IN-1 (Compound 46A) is a sEH/FLAP inhibitor. sEH/FLAP-IN-1 inhibits 5-LOX product formation in SACM-stimulated PBMCs (EC50: 11 nM). sEH/FLAP-IN-1 inhibit sEH (EC50: 18 nM) and thromboxane production. sEH/FLAP-IN-1 can be used for research of inflammatory diseases.

For research use only. We do not sell to patients.

sEH/FLAP-IN-1 Chemical Structure

sEH/FLAP-IN-1 Chemical Structure

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Description

sEH/FLAP-IN-1 (Compound 46A) is a sEH/FLAP inhibitor. sEH/FLAP-IN-1 inhibits 5-LOX product formation in SACM-stimulated PBMCs (EC50: 11 nM). sEH/FLAP-IN-1 inhibit sEH (EC50: 18 nM) and thromboxane production. sEH/FLAP-IN-1 can be used for research of inflammatory diseases[1].

Molecular Weight

446.31

Formula

C19H13Cl2N5O2S

SMILES

ClC1=CC(NC(NC2=CC=C(N=C2)OCC3=NC4=CC=CN=C4S3)=O)=CC=C1Cl

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
sEH/FLAP-IN-1
Cat. No.:
HY-156329
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