2. GPCR/G Protein Neuronal Signaling Immunology/Inflammation
  3. Histamine Receptor
  4. Setastine

Setastine  (Synonyms: EGIS-2062 free acid; EGYT-2062 free acid)

Cat. No.: HY-119832 Purity: 99.21%
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Setastine (EGIS-2062 (free acid); EGYT-2062 (free acid) is an orally effective, non-sedative and long acting anti-allergic agent. Setastine possesses potent histamine Hi-receptor blocking properties and can be used for allergies and rhinitis research[1]<.

For research use only. We do not sell to patients.

Setastine

Setastine Chemical Structure

CAS No. : 64294-95-7

Size Price Stock Quantity
Liquid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Liquid
5 mg In-stock
10 mg In-stock
25 mg In-stock
50 mg In-stock
100 mg In-stock
200 mg   Get quote  
500 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

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Other Forms of Setastine:

Setastine Related Antibodies

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Description

Setastine (EGIS-2062 (free acid); EGYT-2062 (free acid) is an orally effective, non-sedative and long acting anti-allergic agent. Setastine possesses potent histamine Hi-receptor blocking properties and can be used for allergies and rhinitis research[1]<.

IC50 & Target

IC50:Histamine Hi-receptor[1]
Molecular Weight

357.92

Formula

C22H28ClNO
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

CC(C1=CC=C(C=C1)Cl)(OCCN2CCCCCC2)C3=CC=CC=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 125 mg/mL (349.24 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7939 mL 13.9696 mL 27.9392 mL
5 mM 0.5588 mL 2.7939 mL 5.5878 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.7939 mL 13.9696 mL 27.9392 mL 69.8480 mL
5 mM 0.5588 mL 2.7939 mL 5.5878 mL 13.9696 mL
10 mM 0.2794 mL 1.3970 mL 2.7939 mL 6.9848 mL
15 mM 0.1863 mL 0.9313 mL 1.8626 mL 4.6565 mL
20 mM 0.1397 mL 0.6985 mL 1.3970 mL 3.4924 mL
25 mM 0.1118 mL 0.5588 mL 1.1176 mL 2.7939 mL
30 mM 0.0931 mL 0.4657 mL 0.9313 mL 2.3283 mL
40 mM 0.0698 mL 0.3492 mL 0.6985 mL 1.7462 mL
50 mM 0.0559 mL 0.2794 mL 0.5588 mL 1.3970 mL
60 mM 0.0466 mL 0.2328 mL 0.4657 mL 1.1641 mL
80 mM 0.0349 mL 0.1746 mL 0.3492 mL 0.8731 mL
100 mM 0.0279 mL 0.1397 mL 0.2794 mL 0.6985 mL
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Setastine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Setastine64294-95-7EGIS-2062EGYT-2062EGIS2062EGIS 2062EGYT2062EGYT 2062Histamine Receptorallergic rhinoconjunctivitisrhinitis,antihistamine agent?Inhibitorinhibitorinhibit

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