SHP2-IN-23
SHP2-IN-23 (compound 30) is an orally active SHP2 inhibitor (IC50=38 nM) with excellent in vivo efficacy and pharmacokinetic profiles. SHP2-IN-23 inhibits ERK phosphorylation with IC50=5 nM.
For research use only. We do not sell to patients.
- CAS No.: 2415989-91-0
- Formula: C24H23ClN8S
- Molecular Weight:491.01
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IC50: 38 nM (SHP2), 5 nM (pERK)[1]
Chemical Information
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CAS No. 2415989-91-0
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Molecular Weight 491.01
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Formula C24H23ClN8S
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SMILES
N[C@H]1C2(CCN(C3=NC4=C(N=C(C=C4)SC5=CC=NC(N)=C5Cl)N=C3)CC2)CC6=NC=CC=C61
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SHP2-IN-23 Related Classifications
HY-149759 Related Classifications
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