SHP2-IN-23
SHP2-IN-23 (compound 30) is an orally active SHP2 inhibitor (IC50=38 nM) with excellent in vivo efficacy and pharmacokinetic profiles. SHP2-IN-23 inhibits ERK phosphorylation with IC50=5 nM.
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- CAS. Nr.: 2415989-91-0
- Formel: C24H23ClN8S
- Molecular Weight:491.01
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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- Reinheit & Dokumentation
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Help & FAQs
Biologische Aktivität
Beschreibung
IC50 & Target
IC50: 38 nM (SHP2), 5 nM (pERK)[1]
Chemical Information
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CAS. Nr. 2415989-91-0
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Molecular Weight 491.01
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Formel C24H23ClN8S
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SMILES
N[C@H]1C2(CCN(C3=NC4=C(N=C(C=C4)SC5=CC=NC(N)=C5Cl)N=C3)CC2)CC6=NC=CC=C61
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
SHP2-IN-23 Related Classifications
HY-149759 Related Classifications
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