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Art. -Nr.: HY-150298R

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Soquelitinib (Standard)

Name: Soquelitinib (Standard)
Brand: MedChemExpress
SKU: HY-150298R
Availability: PreOrder

(Synonyms: CPI-818 (Standard))

Soquelitinib (Standard) is the analytical standard of Soquelitinib (HY-150298). This product is intended for research and analytical applications. Soquelitinib (CPI-818) is an orally active and highly selective covalent interleuK_in-2-inducible K_inase (ITK) inhibitor. Soquelitinib is active in six different models of T cell-mediated inflammatory and immune disease, including acute and chronic asthma, pulmonary fibrosis, systemic sclerosis (scleroderma), psoriasis, and acute graft versus host disease with Th2 cytoK_ine product inhibition. Soquelitinib increases tumor infiltration of normal CD8⁺ cells that possess enhanced T effector function.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 2226636-04-8
Formel: C₂₅H₃₀N₄O₄S₂
Molecular Weight:514.66

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Soquelitinib (Standard) Chemical Structure

CAS. Nr.: 2226636-04-8

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Product Information
- Information
- Anwendung
Chemical Information
Reinheit & Dokumentation
Calculators
Help & FAQs
Classifications
Bioz

Product Information

Information

Anwendung

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS. Nr. 2226636-04-8
Molecular Weight 514.66
Formel C₂₅H₃₀N₄O₄S₂
SMILES

O=C(N1C[C@H](N(CCC1)C(C=C)=O)C)C2=C(C=C(C(SC3=CN=C(NC(C4CC4)=O)S3)=C2)C)OC
Synonyms

CPI-818 (Standard)
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Hsu L Y, et al. Selective inhibition of interleukin-2 inducible T cell kinase (ITK) enhances anti-tumor immunity in association with Th1-skewing, cytotoxic T cell activation, and reduced T cell exhaustion[J]. bioRxiv, 2023: 2023.07. 05.547822.

[2]. Ding N, et al. Dynamic Single-Cell Profiling Reveals Novel Immune Regulatory Mechanism of ITK Inhibitor Soquelitinib in Refractory T Cell Lymphoma [J]. Blood, 2023, 142: 1442.

[3]. Hsu L Y, et al. Soquelitinb, A selective inhibitor of interleukin-2-inducible kinase (ITK), is active in several murine models of T cell-mediated inflammatory disease[J]. bioRxiv, 2023: 2023.10. 27.564296.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

Minimum order quantity

100 mg

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