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Cat. No.: HY-117770

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STAT3-IN-30

STAT3-IN-30 (compound 9c) is a STAT3 inhibitor with an EC₅₀ of 13.8 μM.

For research use only. We do not sell to patients.

CAS No.: 1803281-30-2
Formula: C₃₆H₃₀F₈N₂O₆S
Molecular Weight:770.69

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

STAT3-IN-30 Chemical Structure

CAS No.: 1803281-30-2

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

STAT3-IN-30 (compound 9c) is a STAT3 inhibitor with an EC₅₀ of 13.8 μM^[1].

All STAT Isoforms :

Chemical Information

CAS No. 1803281-30-2
Molecular Weight 770.69
Formula C₃₆H₃₀F₈N₂O₆S
SMILES

O=C(O)C1=CC=C(N(CC2=CC=C(C3CCCCC3)C=C2)C(CN(CC4=C(F)C(F)=C(F)C(F)=C4F)S(=O)(C5=CC=C(C(F)(F)F)C=C5)=O)=O)C=C1O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Eiring AM, et al. Combined STAT3 and BCR-ABL1 inhibition induces synthetic lethality in therapy-resistant chronic myeloid leukemia. Leukemia. 2015 Mar;29(3):586-597. doi: 10.1038/leu.2014.245. Epub 2014 Aug 19. Erratum in: Leukemia. 2017 May;31(5):1253-1254. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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STAT3-IN-30

All STAT Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

STAT3-IN-30 Related Classifications

HY-117770 Related Classifications