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Cat. No.: HY-123387

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Suksdorfin

Suksdorfin is a compound isolated from the fruits of Lomatium suksdorfii. Suksdorfin has activity againstHIV-1.

For research use only. We do not sell to patients.

CAS No.: 53023-17-9
Formula: C₂₁H₂₄O₇
Molecular Weight:388.41

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

Suksdorfin Chemical Structure

CAS No.: 53023-17-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Suksdorfin is a compound isolated from the fruits of Lomatium suksdorfii. Suksdorfin has activity againstHIV-1^[1].

All HIV Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
H9	EC₅₀	1.3 μM Compound: 132	Antiviral activity against HIV1 3B infected in H9 cells assessed as inhibition of viral replication by p24 antigen ELISA Antiviral activity against HIV1 3B infected in H9 cells assessed as inhibition of viral replication by p24 antigen ELISA	[PMID: 20187635]
H9	EC₅₀	1.3 μM Compound: Suksdorfin (1)	Effective concentration against HIV-1 replication in H9 lymphocyte cells was determined Effective concentration against HIV-1 replication in H9 lymphocyte cells was determined	10.1016/S0960-894X(01)80161-X
H9	IC₅₀	>52 μM Compound: Suksdorfin (1)	Compound was tested for inhibitory activity against HIV-1 replication in H9 lymphocyte cells Compound was tested for inhibitory activity against HIV-1 replication in H9 lymphocyte cells	10.1016/S0960-894X(01)80161-X
Hepatocyte	IC₅₀	>100 μM Compound: 8	Inhibitory activity against D-GalN-induced cytotoxicity in rat hepatocytes Inhibitory activity against D-GalN-induced cytotoxicity in rat hepatocytes	[PMID: 9873511]

Chemical Information

CAS No. 53023-17-9
Molecular Weight 388.41
Formula C₂₁H₂₄O₇
SMILES

CC(CC(O[C@@H]1C2=C3C(C=CC(O3)=O)=CC=C2OC(C)([C@@H]1OC(C)=O)C)=O)C
Structure Classification
- Others
Initial Source
- Plants
- Umbelliferae
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Lee TT, et al. Suksdorfin: an anti-HIV principle from Lomatium suksdorfii, its structure-activity correlation with related coumarins, and synergistic effects with anti-AIDS nucleosides. Bioorg Med Chem. 1994 Oct;2(10):1051-6. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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