SW063058
SW063058 is an autophagy inducer that specifically disrupts the binding of Beclin 1 to Bcl-2 while leaving the interaction between Bcl-2 and pro-apoptotic members like Bax and BIM unaffected. By inhibiting the negative regulatory effects of Bcl-2 on Beclin 1, which is crucial for the initiation of autophagy, SW063058 promotes autophagic activity without triggering cytotoxicity, apoptosis, or other forms of cell death in vitro.
For research use only. We do not sell to patients.
- CAS No.: 533876-30-1
- Formula: C22H15BrFIN2O2
- Molecular Weight:565.17
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 533876-30-1
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Molecular Weight 565.17
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Formula C22H15BrFIN2O2
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SMILES
O=C1NC2=CC=C(C=C2C(N(C1)C(C3=C(I)C=CC=C3)=O)C4=CC=C(C=C4)F)Br
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)