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  3. TASP0277308

TASP0277308 is a highly selective S1P1 antagonist. TASP0277308 possesses immunomodulatory activities, including lymphopenia, a block in T cell egress from the thymus, marginal zone B cell displacement, and the upregulation of CD69 expression on lymphocytes. TASP0277308 can be used for the research of collagen-induced arthritis in mice.

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TASP0277308 Chemical Structure

TASP0277308 Chemical Structure

CAS No. : 945725-50-8

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Description

TASP0277308 is a highly selective S1P1 antagonist. TASP0277308 possesses immunomodulatory activities, including lymphopenia, a block in T cell egress from the thymus, marginal zone B cell displacement, and the upregulation of CD69 expression on lymphocytes. TASP0277308 can be used for the research of collagen-induced arthritis in mice[1].

Molecular Weight

539.48

Formula

C23H28Cl2N6O3S

CAS No.
SMILES

CCN1C(OC2=CC(N3CCN(CC3)C)=CC=C2)=NN=C1[C@@H](C)NS(=O)(C4=CC(Cl)=C(C=C4)Cl)=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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TASP0277308 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
TASP0277308
Cat. No.:
HY-18164
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