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Cat. No.: HY-189100

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TEAD-IN-26

TEAD-IN-26 is a TEAD inhibitor for research on TEAD-related diseases, such as cancer and chronic pain.

For research use only. We do not sell to patients.

CAS No.: 2851524-04-2
Formula: C₁₈H₁₇F₃N₄O₄
Molecular Weight:410.35

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

TEAD-IN-26 Chemical Structure

CAS No.: 2851524-04-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
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- In Vitro
Chemical Information
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Biological Activity

Description

TEAD-IN-26 is a TEAD inhibitor for research on TEAD-related diseases, such as cancer and chronic pain^[1].

IC₅₀ & Target

^[1]

TEAD

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In Vitro

TEAD-IN-26 (Compound 130) is obtained by reacting 2-methoxy-5-((5-(trifluoromethyl) pyridin-2-yl) oxy) aniline with (S)-3-methyl-2-oxoimidazolidine-4-carboxylic acid^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2851524-04-2
Molecular Weight 410.35
Formula C₁₈H₁₇F₃N₄O₄
SMILES

O=C([C@H]1N(C(NC1)=O)C)NC2=C(C=CC(OC3=CC=C(C=N3)C(F)(F)F)=C2)OC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Ahlmark M, et al. Tead inhibitors. WO patent, WO2022219246A1. 2022.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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- In Vitro
Chemical Information
Purity & Documentation
References

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TEAD-IN-26

All YAP Isoforms

Biological Activity

Description

IC50 & Target

In Vitro

Chemical Information

Purity & Documentation

References

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Help & FAQs

TEAD-IN-26 Related Classifications

HY-189100 Related Classifications

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