Thalidomide-4-O-C4-Br
Thalidomide-4-O-C4-Br is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based CRBN ligand and a linker used in PROTAC technology. Thalidomide-4-O-C4-Br can be connected to the ligand for protein by a linker to form PROTAC EZH2 Degrader-10 (HY-181305).
For research use only. We do not sell to patients.
- CAS No.: 2653338-51-1
- Formula: C17H17BrN2O5
- Molecular Weight:409.23
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
All E3 Ligase Ligand-Linker Conjugates Isoforms
More
Biological Activity
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 2653338-51-1
-
Molecular Weight 409.23
-
Formula C17H17BrN2O5
-
SMILES
BrCCCCOC1=C2C(N(C3CCC(NC3=O)=O)C(C2=CC=C1)=O)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Powered by Bioz