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Cat. No.: HY-172114

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Thalidomide-4-piperidineacetaldehyde

Thalidomide-4-piperidineacetaldehyde is an E3 ligase ligand and linker conjugate and can be used to synthesize PROTAC H122 (HY-172113).

For research use only. We do not sell to patients.

CAS No.: 2222115-36-6
Formula: C₂₀H₂₁N₃O₅
Molecular Weight:383.40

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

Thalidomide-4-piperidineacetaldehyde Chemical Structure

CAS No.: 2222115-36-6

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Thalidomide-4-piperidineacetaldehyde is an E3 ligase ligand and linker conjugate and can be used to synthesize PROTAC H122 (HY-172113)^[1].

All E3 Ligase Ligand-Linker Conjugates Isoforms :

Chemical Information

CAS No. 2222115-36-6
Molecular Weight 383.40
Formula C₂₀H₂₁N₃O₅
SMILES

O=C(CC1)NC(C1N(C2=O)C(C(C2=C3)=CC=C3N(CC4)CCC4CC=O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Lu Y, et al. Selective Degradation of TEADs by a PROTAC Molecule Exhibited Robust Anticancer Efficacy In Vitro and In Vivo. J Med Chem. 2025 Jan 13. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Thalidomide-4-piperidineacetaldehyde

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References

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Thalidomide-4-piperidineacetaldehyde

All E3 Ligase Ligand-Linker Conjugates Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Thalidomide-4-piperidineacetaldehyde Related Classifications

HY-172114 Related Classifications