Thalidomide-N-methylpiperazine
Based on 1 Customer Validation
Thalidomide-N-methylpiperazine is an E3 Ligase Ligand-Linker Conjugate. Thalidomide-N-methylpiperazine can be used to synthesize PROTAC MLKL Degrader-2 (HY-169072) to exhibit antinecroptotic activity on human cell lines and effectively degrade MLKL in the HT-29 xenograft mouse model.
For research use only. We do not sell to patients.
- Purity : 99.79%
- CAS No.: 2924858-30-8
- Formula: C18H20N4O4
- Molecular Weight:356.38
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
Description
Chemical Information
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CAS No. 2924858-30-8
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Appearance Solid
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Molecular Weight 356.38
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Formula C18H20N4O4
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SMILES
CN1CCN(C2=CC3=C(C=C2)C(N(C3=O)C4CCC(NC4=O)=O)=O)CC1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)