TLR7 agonist 17
TLR7 agonist 17 (compound 20) is a potent TLR7 agonist with EC50 values of 12 nM and 17 nM for hTLR7 and mTLR7, respectively. TLR7 agonist 17 shows anticancer activity.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2410517-32-5
- 分子式: C25H37N7O3
- 分子量:483.61
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
生物活性
製品説明
IC50 & Target
[1]|
human TLR7 12 nM (EC50) |
mTLR7 17 nM (EC50) |
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| T-cell | IC50 |
>25 μM
Compound: 20
|
Cytotoxicity against PHA-activated T cells (unknown origin) assessed as inhibition of IL-2 induced cell proliferation by PHA-blast assay
Cytotoxicity against PHA-activated T cells (unknown origin) assessed as inhibition of IL-2 induced cell proliferation by PHA-blast assay
|
[PMID: 38352830] |
化学情報
-
CAS 番号 2410517-32-5
-
分子量 483.61
-
分子式 C25H37N7O3
-
SMILES
NC1=NC(N[C@H](CCO)CCC)=C(N(CC2=C(OC)C=C(CNC3CCOCC3)C=C2)N=C4)C4=N1
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
TLR7 agonist 17 関連分類
HY-162115 関連分類
Powered by Bioz
Keywords